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ProteomicsLC-MSMSMass Spectrometric detection of SARS-CoV-2 virus in scrapings of the epithelium of the nasopharynx of infected patients via Nucleocapsid N protein
Detection of viral RNA by PCR is currently the main diagnostic tool for COVID-191. The PCR-based test, however, shows limited sensitivity, especially at early and late stages of the disease development, and is relatively time consuming. Fast and reliable complementary methods for detecting the viral...
ORGANISM(S): Severe acute respiratory syndrome coronavirus 2 
2020-08-14 | PXD019648 | Pride
Covid Covid-19 Proteomics Sars-cov-2 
ProteomicsA First-Trimester Serum Proteomic Signature for Early Predic-tion of Preeclampsia: Integrated Untargeted and Targeted Mass Spectrometry with Machine Learning
First-trimester prediction of preeclampsia (PE) remains a major clinical challenge, par-ticularly outside specialized fetal medicine centers. This study aimed to identify and validate serum protein biomarkers for early PE prediction using an integrated proteo-mic approach. A prospective cohort of 64...
ORGANISM(S): Homo sapiens (Human) 
2026-09-14 | PXD080843 | Pride
Preeclampsia  first-trimester screening  serum proteomics  prognosis  dia-ms  mrm-ms  machine learning  biomarkers  complement system  mass spectrometry. 
UnknownPotential Urine Proteomic Biomarkers for Focal Segmental Glomerulosclerosis and Minimal Change Disease.
Not available
S-EPMC9604469 | biostudies-literature
UnknownTargeted MRM Quantification of Urinary Proteins in Chronic Kidney Disease Caused by Glomerulopathies.
Not available
S-EPMC10142111 | biostudies-literature
ProteomicsThe secretome of cultured human endothelial cells in modelled microgravity
Using chromatography-mass spectrometry on an Ultimate 3000 chromatograph combined with a Maxis 4G mass spectrometer, the secretome of human umbilical vein endothelial cells (HUVEC) cultured under static conditions and modeling microgravity for 24 hours was studied. In the secretome of cells under mi...
ORGANISM(S): Homo sapiens (Human) 
2026-07-01 | PXD013497 | Pride
Endothelial cells Microtubules Rho-gtpases Secretome Chromatography-mass spectrometry 
UnknownCID fragmentation, H/D exchange and supermetallization of Barnase-Barstar complex.
Not available
S-EPMC5522418 | biostudies-literature
UnknownTargeted Blood Plasma Proteomics and Hemostasis Assessment of Post COVID-19 Patients with Acute Myocardial Infarction.
Not available
S-EPMC10094800 | biostudies-literature
UnknownUbiquitin-independent proteosomal degradation of myelin basic protein contributes to development of neurodegenerative autoimmunity.
Not available
S-EPMC4415016 | biostudies-literature
ProteomicsOxidized fibrinogen HPLC-MS/MS
Fibrinogen is highly susceptible to oxidation compared to other plasma proteins. Fibrinogen oxidation damages its structure and affects the protein function. Fibrinogen was isolated from citrated human plasma by the modified cold ethanol precipitation technique. Oxidation of fibrinogen by ozone: a s...
ORGANISM(S): Homo sapiens (Human) 
2019-04-04 | PXD012046 | Pride
Oxidation Hplc-ms/ms Fibrinogen Oxidative post-translational modifications 
ProteomicsChr18 Consortium MS-data for missing proteins mining
Despite direct or indirect efforts of proteomic community, the fraction of blind spots on the protein map is still significant. Almost 10% (?) of human master protein has no experimental validation up to now. Apparently, proteomics has reached the stage where all easy scores are achieved (?), and ev...
ORGANISM(S): Homo sapiens (Human) 
2020-06-03 | PXD014300 | Pride
Mass-spectrometry Uncertain proteins Missing proteins Chromosome-centric human proteome project (с-hpp) Human proteome Proteotypic peptide Nextprot 
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