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ProteomicsTwo-Step Co-Immunoprecipitation (TIP) Enables an Efficient and Highly Selective Isolation of Native Protein-Complexes
Co-immunoprecipitation (co-IP) is the most frequently used technique for the isolation of protein-protein (PPI) or protein-nucleic acid interactions (PNI) under native expression conditions. A major disadvantage of co-IP is the abundance of non-specific binders that can impede downstream application...
ORGANISM(S): Homo sapiens (Human) 
2018-01-11 | PXD006700 | Pride
Immunoprecipitation Bridging Co-immunoprecipitation Monoclonal Nfkb Co-ip Btip Chip Primary cells Antibody Tip Polyclonal Ikk Chromatin Cd95 
MetabolomicsFeatures of acute COVID-19 associated with post-acute sequelae of SARS-CoV-2 phenotypes: results from the IMPACC study
Post-acute sequelae of SARS-CoV-2 (PASC) is a significant public health concern. We describe Patient Reported Outcomes (PROs) on 590 participants prospectively assessed from hospital admission for COVID-19 through one year after discharge. Modeling identified 4 PRO clusters based on reported deficit...
2024-01-12 | MTBLS850 | MetaboLights
ProteomicsA General Approach for Activity-based Protein Profiling of Oxidoreductases with Redox-differentiated Diarylhalonium Warheads
Activity-based protein profiling (ABPP) is a unique proteomic tool for measuring the activity of enzymes in their cellular context, which has been well established for enzyme classes exhibiting a characteristic nucleophilic residue (e.g. hydrolases). In contrast, the enzyme class of oxidoreductases ...
ORGANISM(S): Mus musculus (Mouse) 
2025-05-06 | PXD043873 | Pride
Oxidoreductase probe Mouse liver; Activity-based protein profiling 
ProteomicsProteomics and phosphoproteomics of SARS-CoV-2 and IAV treated APCs
The clinical course of SARS-CoV-2 infection is highly variable with a subset of patients developing severe COVID-19 and acute respiratory distress syndrome (ARDS). COVID-19 induced lung injury and respiratory failure appears to be driven by dysregulated immune responses, yet the exact mechanisms rem...
ORGANISM(S): Influenza A virus (A/Panama/2007/1999(H3N2)) Homo sapiens (Human) Severe acute respiratory syndrome coronavirus 2 
2021-11-29 | PXD022709 | Pride
Iav Tmt Sars-cov-2 Apc Phosphoproteomics Pbmc 
UnknownSearch for heavy neutrinos and [Formula: see text] bosons with right-handed couplings in proton-proton collisions at [Formula: see text].
Not available
S-EPMC4371073 | biostudies-literature
UnknownMeasurement of the differential cross section for top quark pair production in pp collisions at [Formula: see text].
Not available
S-EPMC4657759 | biostudies-literature
UnknownSearch for supersymmetry in pp collisions at [Formula: see text] TeV in events with a single lepton, jets, and missing transverse momentum.
Not available
S-EPMC4370766 | biostudies-literature
UnknownElliptic anisotropy measurement of the f<sub>0</sub>(980) hadron in proton-lead collisions and evidence for its quark-antiquark composition.
Not available
S-EPMC12391314 | biostudies-literature
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