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ProteomicsSerum proteomics of sng- and pain-trend fibromyalgia patients
Fibromyalgia (FM) is a chronic pain condition and consists of widespread pain with similarities to neuropathic pain in clinical findings, pathophysiology, and neuropharmacology. Its mechanisms are poorly understood and a lack of effective biomarkers for diagnosis and onset prediction. This study aim...
ORGANISM(S): Homo sapiens (Human) 
2022-08-12 | PXD022886 | Pride
Serum Fibromyalgia 
ProteomicsPhosphoproteomics of Human ACHN cells by estrogen
To find out the potential targets in response to estrogen treatment on ACHN cell, a human renal cell carcinoma (RCC) cell line. Since estrogen can repress ACHN growth in a partly estrogen receptor-dependent manner, it is possible that phosphorylation state in ACHN cells is regulated.
ORGANISM(S): Homo sapiens (Human) 
2016-04-26 | PXD001962 | Pride
Estrogen Rcc Phosphoproteomics 
ProteomicsQuantitative phosphoproteomics of chronic sunitinib treated renal cell carcinoma 786-O cells with GPR30 agonist G-1
In this project, we generated chronic sunitinib-treated 786-O cell, a renal cell carcinoma cell line. In order to investigate the possible effect of GPR30 agonist, G-1, on the growth-inhibtion related signaling pathways, we treated either parental both parental and chronic sunitinib-treated 786-O ce...
ORGANISM(S): Homo sapiens (Human) 
2021-04-28 | PXD021254 | Pride
Renal cell carcinoma Sunitinib Gpr30 
ProteomicsProteomic profiling of dysferlin microdeletion–induced skeletal muscle remodeling in a knock-in mouse model
This project examines the proteomic impact of dysferlin deficiency using a genetically defined knock-in mouse model carrying a five-nucleotide microdeletion in the Dysf gene that corresponds to a pathogenic variant identified in limb-girdle muscular dystrophy type R2 (LGMD-R2) patients. Dysferlin is...
ORGANISM(S): Mus musculus (Mouse) 
2026-04-09 | PXD073710 | Pride
Dysferlinopathy  limb-girdle muscular dystrophy  skeletal muscle proteomics  dia-pasef mass spectrometry 
Proteomicskaempferitrin-induced secretome analyses in rat CTX TNA2 astrocytic cell line
Kaempferitrin is extracted at significant quantity from leaves of Cinnamomum osmophloeum. People consuming extract containing kaempferitrin often happen to be of high risk for diabetes and neurodegenerative diseases. For kaempferitrin to be used every day for them, the systematic effect, especially ...
ORGANISM(S): Rattus norvegicus (Rat) 
2017-11-24 | PXD002814 | Pride
Kaempferitrin Secretome Lc-ms/ms Astrocyte 
ProteomicsMouse CSF Analyses of middle cerebral ischemic/reperfusion (CI/R) injury followed by Buyang Huanwu Decoction
Ischemic stroke is one of the most common causes of death worldwide and a major cause of acquired disability in adults. Buyang Huanwu decoction (BHD), a traditional Chinese medicine prescription, has long been used clinically for neurological recovery after stroke. Its molecular characteristics and ...
ORGANISM(S): Mus musculus (Mouse) 
2019-02-16 | PXD006342 | Pride
Mouse csf Chinese herb medicine Buyang huanwu decoction Ischemic stroke 
ProteomicsExosomal markers in secretome of Kamepferitrin-treated HepG2 cells
Kaempferitrin is extracted in significantly high quantities from the leaves of Cinnamomum osmophloeum, which belongs to the genus Cinnamomum, the same genus many antidiabetic herbal remedy in Chinese medicine. Oral administration of kaempferitrin reduces blood sugar in alloxan-induced diabetic rats....
ORGANISM(S): Homo sapiens (Human) 
2021-02-01 | PXD022181 | Pride
Human Kamepferitrin Secretome 
ProteomicsQuantitative proteomics of melanoma metastases derived from adherent cells or suspended cells.
Detachment of melanoma and survival under anchorage-independency were recognized as initial step of tumor metastasis. Our previous studies showed altered gene expression contributed to loss of cell invasiveness, enhanced chemosensitivity, and enhanced subcutaneous tumor formation. In this study, we ...
ORGANISM(S): Homo sapiens (Human) 
2020-08-07 | PXD011883 | Pride
Human Melanoma Anchorage independency 
ProteomicsProteomic study on human breast cancer cells in response to different folate levels
The consequence of a supra-physiological folate tumour microenvironment in promoting metastasis potential of human breast cancers remains unexplored. This study examined the molecular mechanism by which clinically aberrant folate levels may promote mitochondria and glycolytic stress-associated prot...
ORGANISM(S): Homo sapiens (Human) 
2022-11-21 | PXD011046 | Pride
Human Breast cancer Folate 
UnknownRobust estimation of bacterial cell count from optical density.
Not available
S-EPMC7499192 | biostudies-literature
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