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ProteomicsProline: an efficient and user-friendly software suite for large-scale proteomics
We present Proline (http://www.profiproteomics.fr/proline/), a robust software suite for analysis of MS-based proteomics data; it provides high performance in a user-friendly interface for all data set sizes from small to very large
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2020-03-03 | PXD009815 | Pride
Label free quantification data management software proline 
UnknownProline: an efficient and user-friendly software suite for large-scale proteomics.
Not available
S-EPMC7214047 | biostudies-literature
ProteomicsRegulation of mechanical intercellular junctions and components of the mitochondrial electron transport chain and the TCA cycle in the hypertrophic heart by pyridostigmine or trandolapril
The conventional approach to studying hypertension and cardiac hypertrophy primarily focuses on electrochemical signaling mediated by gap junctions. However, mechanical adherens junctions also contribute to hypertrophy through activation of β-catenin, promoting transcription of growth-inducing genes...
ORGANISM(S): Rattus norvegicus (Rat) 
2026-09-07 | PXD076994 | Pride
Hypertrophy Pyridostigmine Trandolapril Electron transport chain Tca cycle Shr rats Desmosome Adherens junction Sarcomere 
ProteomicsDiagnosis of hepatocellular adenomas and malignancy determination by proteomic patterns matching (5)
Biopsies are underrated and underused and our goal was to demonstrate that their inherent expression proteomic pattern could give them an added value for diagnosis. As proof of concept, we used as model hepatocellular adenomas (HCA), well characterized benign liver tumors. From a collection of 260 ...
ORGANISM(S): Homo sapiens (Human) 
2021-06-11 | PXD023000 | Pride
Patterns matching Biopsies Machine learning Clinical proteomics Diagnosis Hepatocellular adenomas Malignancy 
ProteomicsDiagnosis of hepatocellular adenomas and malignancy determination by proteomic patterns matching (1)
Biopsies are underrated and underused and our goal was to demonstrate that their inherent expression proteomic pattern could give them an added value for diagnosis. As proof of concept, we used as model hepatocellular adenomas (HCA), well characterized benign liver tumors. From a collection of 260 c...
ORGANISM(S): Homo sapiens (Human) 
2021-06-11 | PXD022835 | Pride
Patterns matching Biopsies Machine learning Clinical proteomics Diagnosis Hepatocellular adenomas Malignancy 
ProteomicsDiagnosis of hepatocellular adenomas and malignancy determination by proteomic patterns matching (4)
Biopsies are underrated and underused and our goal was to demonstrate that their inherent expression proteomic pattern could give them an added value for diagnosis. As proof of concept, we used as model hepatocellular adenomas (HCA), well characterized benign liver tumors. From a collection of 260 c...
ORGANISM(S): Homo sapiens (Human) 
2021-06-11 | PXD022844 | Pride
Patterns matching Biopsies Machine learning Clinical proteomics Diagnosis Hepatocellular adenomas Malignancy 
ProteomicsDiagnosis of hepatocellular adenomas and malignancy determination by proteomic patterns matching (3)
Biopsies are underrated and underused and our goal was to demonstrate that their inherent expression proteomic pattern could give them an added value for diagnosis. As proof of concept, we used as model hepatocellular adenomas (HCA), well characterized benign liver tumors. From a collection of 260 c...
ORGANISM(S): Homo sapiens (Human) 
2021-06-11 | PXD022839 | Pride
Patterns matching Biopsies Machine learning Clinical proteomics Diagnosis Hepatocellular adenomas Malignancy 
ProteomicsDiagnosis of hepatocellular adenomas and malignancy determination by proteomic patterns matching (2)
Biopsies are underrated and underused and our goal was to demonstrate that their inherent expression proteomic pattern could give them an added value for diagnosis. As proof of concept, we used as model hepatocellular adenomas (HCA), well characterized benign liver tumors. From a collection of 260 c...
ORGANISM(S): Homo sapiens (Human) 
2021-06-11 | PXD022837 | Pride
Patterns matching Biopsies Machine learning Clinical proteomics Diagnosis Hepatocellular adenomas Malignancy 
ProteomicsThe Urinary Peptidome Identifies Prognostic Biomarkers for Small Renal Masses
Purpose: Renal cell carcinoma (RCC) is often diagnosed incidentally as an early-stage small renal mass (SRM; pT1a, ≤ 4 cm). Increasing concerns surrounding the overtreatment of patients with benign or clinically indolent tumors has led to a shift in current treatment recommendations, especially for ...
ORGANISM(S): Homo sapiens (Human) 
2019-08-08 | PXD013111 | Pride
Urine Mass spectrometry Peptidomics Clear cell renal cell carcinoma Small renal mass 
ProteomicsBioinformatics and mass spectrometry-based proteomics reveal alcohol dehydrogenase 1B as a blood biomarker candidate to monitor acetaminophen-induced liver injury
Acute liver injury (ALI) is a severe disorder resulting from excessive hepatocyte cell death and frequently caused by acetaminophen intoxication. Clinical management of ALI progression is hampered by the dearth of blood biomarkers available. In this study, a bioinformatics workflow was developed to ...
ORGANISM(S): Homo sapiens (Human) 
2021-11-29 | PXD028082 | Pride
Proteomics  mass spectrometry  liver  blood  biomarker  acetaminophen 
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