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ProteomicsLable-free LC-MSMS in HeLa on DYRK3 and Sec16A, Human cervical cancer cells
In order to identify sites of the SEC16A specifically phosphorylated by the Dual Specificity Kinase DYRK3, mCherry-SEC16A was transiently over expressed in HeLa cells together with GFP-DYRK3 or EGFP-C1 only
ORGANISM(S): Homo sapiens (Human) 
2023-06-23 | PXD041620 | Pride
Hela Lable-free lc-msms Dyrk3 Sec16a 
ProteomicsPanax japonicus C. A. Myer LC-MSMS
Ginsenosides are a class of natural product triterpene saponins and almost exclusively in the plant genus Panax which has a long history of use as dietary supplements. Pharmacological research demonstrated that ginsenosides have multiple bioactivities. Ginsenoside is produced at high levels within P...
ORGANISM(S): Panax japonicus 
2023-02-09 | PXD038579 | Pride
Panax japonicus c. a. myer lc-msms 
ProteomicsAPEX1 alters the phospho-landscape of SKOV3 cells
APEX1 overexpression and knockdown cell lines were established based on SKOV3 cell line. Lable-free quantitative phosphoproteomics was done to evaluate the impact of APEX1 on cellular phosphoproteomics
ORGANISM(S): Homo sapiens (Human) 
2024-05-22 | PXD040041 | Pride
Lc-msms  phosphoproteomics 
ProteomicsProbing the biogenesis pathway and dynamics of thylakoid membranes_C4PR_LIV
Thylakoid membranes are the specialized internal membrane system produced in plants, algae, and cyanobacteria to convert sunlight to chemical energy via oxygenic photosynthesis. Cyanobacterial thylakoid membranes harbor the protein complexes and electron transport molecules that are necessary for ph...
ORGANISM(S): Synechococcus elongatus (strain PCC 7942) (Anacystis nidulans R2) 
2020-11-17 | PXD019731 | Pride
Biogenesis Thylakoid membrane Cyanobacteria Light regulation Photosynthesis Synechococcus elongatus 
ProteomicsMass Spectrometry analysis of human matched Anterior and Posterior lobes of Pituitary
This study provides a comprehensive proteomic analysis of five matched pairs of the anterior and posterior lobe of the pituitary, which was used to study the proteomic signature specific to both anterior and posterior lobes. Anterior Lobe n=5 Posterior Lobe n=5 A441 PT441 A442 ...
ORGANISM(S): Homo sapiens (Human) 
2022-12-07 | PXD030235 | Pride
Pituitary Label free quantification lfq Proteomics Obribtrap based mass spectrometery analysis Lc-msms 
ProteomicsA HEV ORF2 protein-mediated mechanism of hepatitis E-associated kidney disease
Hepatitis E virus (HEV) infection, one of the most common forms of hepatitis worldwide, is often associated with extrahepatic, particularly renal, manifestations. However, the underlying mechanisms are incompletely understood. Here, we report the development of a de novo immune complex-mediated glom...
ORGANISM(S): Homo sapiens (Human) 
2025-01-18 | PXD055348 | Pride
Infected or not with hepatitis e virus. laser-captured samples Lc-msms Human liver and kidney samples 
ProteomicsLabel-free quantification of proteins in wild type and CLPP-null mouse embryonic fibroblasts
We studied consequences of genetic deletion of mitochondrial peptidase CLPP for global proteome profile in unstressed cells.
ORGANISM(S): Mus musculus (Mouse) 
2022-02-16 | PXD023677 | Pride
Mitochondrial accumulation of ribosomes and nucleoids Basal innate immunity elevation Vdac-dependent release Antiviral state Lc-msms Cgas-sting-irf7-ifnb-stat1 activation 
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