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UnknownHistamine signaling and metabolism identify potential biomarkers and therapies for lymphangioleiomyomatosis
Not available
S-SCDT-EMM-2021-13929 | biostudies-other
TranscriptomicsVitamin D receptor (VDR) regulates epidermal stem cells and cutanous wound healing [keratinocytes]
The vitamin D receptor (VDR) regulates cell proliferation and differentiation including epidermal keratinocytes by modulating transcription of its target genes. We are investigating the role of VDR in epidermal stem cells and their progenies in the regeneration process of epidermis and hair in the s...
ORGANISM(S): Mus musculus 
2015-07-31 | E-GEOD-68729 | biostudies-arrayexpress
TranscriptomicsSynergism of calcium sensing receptor and vitamin D receptor mediated signaling in epidermal differentiation [VDR KO]
Calcium and 1,25-dihydroxyvitamin D3 (1,25D3), through the actions of their respective receptors, the Ca2+-sensing receptor (CaSR) and the vitamin D receptor (VDR), potentiate keratinocyte differentiation. VDR regulates epidermal keratinocyte proliferation and differentiation by modulating gene tran...
ORGANISM(S): Mus musculus 
2015-07-31 | E-GEOD-68723 | biostudies-arrayexpress
TranscriptomicsSynergism of calcium sensing receptor and vitamin D receptor mediated signaling in epidermal differentiation [double KO]
Calcium and 1,25-dihydroxyvitamin D3 (1,25D3), through the actions of their respective receptors, the Ca2+-sensing receptor (CaSR) and the vitamin D receptor (VDR), potentiate keratinocyte differentiation. VDR regulates epidermal keratinocyte proliferation and differentiation by modulating gene tran...
ORGANISM(S): Mus musculus 
2015-07-31 | E-GEOD-68725 | biostudies-arrayexpress
TranscriptomicsVitamin D receptor (VDR) regulates epidermal stem cells and cutanous wound healing [VDR KO]
The vitamin D receptor (VDR) regulates cell proliferation and differentiation including epidermal keratinocytes by modulating transcription of its target genes. We are investigating the role of VDR in epidermal stem cells and their progenies in the regeneration process of epidermis and hair in the s...
ORGANISM(S): Mus musculus 
2015-07-31 | E-GEOD-68727 | biostudies-arrayexpress
TranscriptomicsVitamin D receptor (VDR) regulates epidermal stem cells and cutanous wound healing [BKO]
The vitamin D receptor (VDR) regulates cell proliferation and differentiation including epidermal keratinocytes by modulating transcription of its target genes. We are investigating the role of VDR in epidermal stem cells and their progenies in the regeneration process of epidermis and hair in the s...
ORGANISM(S): Mus musculus 
2015-07-31 | E-GEOD-68728 | biostudies-arrayexpress
TranscriptomicsSynergism of calcium sensing receptor and vitamin D receptor mediated signaling in epidermal differentiation [CaSR KO]
Calcium and 1,25-dihydroxyvitamin D3 (1,25D3), through the actions of their respective receptors, the Ca2+-sensing receptor (CaSR) and the vitamin D receptor (VDR), potentiate keratinocyte differentiation. VDR regulates epidermal keratinocyte proliferation and differentiation by modulating gene tran...
ORGANISM(S): Mus musculus 
2015-07-31 | E-GEOD-68724 | biostudies-arrayexpress
ProteomicsDevelopmental mRNA clearance by PIWI-bound endo-siRNAs in Paramecium
The clearance of untranslated mRNAs by Argonaute proteins is essential for embryonic development in metazoans. However, it is currently unknown whether a similar process exists in unicellular eukaryotes. The ciliate Paramecium tetraurelia harbors a vast array of Argonaute proteins of the Piwi-clade ...
ORGANISM(S): Paramecium tetraurelia 
2023-05-10 | PXD038984 | Pride
Paramecium tetraurelia Piwi Mrna clearance Untranslated mrna Total protein < 25kda Sirnas 
MetabolomicsAntibiotics create a shift from mutualism to competition in human gut communities with a longer-lasting impact on fungi than bacteria

Background

Antibiotic treatment has a well-established detrimental effect on the gut bacterial composition, but effects on the fungal community are less clear. Bacteria in the lumen of the gastrointestinal tract may limit fungal colonization and invasion. Antibiotic drugs t...

2020-09-28 | MTBLS1846 | MetaboLights
TranscriptomicsTranscription profiling of rat Tsc2 mutant (Eker) vs. wild type treated with aristolochic acid and ochratoxin A
Renal gene expression profiles of Eker and wild type rats, gavaged with AA or OTA, respectively for 1, 3, 7 or 14 days; We used Affymetrix RAE230A microarrays for the analysis of early gene expression changes in the renal cortex_ outer medulla of carcinogen treated Eker and corresponding wild type r...
ORGANISM(S): Rattus norvegicus 
2008-06-14 | E-GEOD-5923 | biostudies-arrayexpress
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