Langer T T - OmicsDI

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Unknown (735)
Proteomics (89)
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Homo sapiens (67)
Mus musculus (39)
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Thermus thermophilus HB27 (1)

Organisms

Homo sapiens (1)

Repository

pride (83)
biostudies-arrayexpress (45)
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Tissue

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Disease

Simpson-Golabi-Behmel syndrome type 1 (2)
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Technology Type

Mass Spectrometry (83)
Shotgun proteomics (38)
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Affinity purification coupled with mass spectrometry proteomics (9)
SWATH MS (9)
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Chemical cross-linking coupled with mass spectrometry proteomics (3)
Mass spectrometry assay (1)

Instrument Platform

Liquid Chromatography MS - negative - reverse phase (3)
Liquid Chromatography MS - positive - reverse phase (3)
NextSeq 550 (1)
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LTQ Orbitrap (1)
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CHEBI ID

CHEBI:16750 (3)
CHEBI:17368 (3)
CHEBI:17596 (3)
CHEBI:15611 (2)
CHEBI:15741 (2)
CHEBI:15756 (2)
CHEBI:15940 (2)
CHEBI:16027 (2)
CHEBI:16196 (2)
CHEBI:16235 (2)
CHEBI:16264 (2)
CHEBI:16335 (2)
CHEBI:16704 (2)
CHEBI:16708 (2)
CHEBI:16737 (2)
CHEBI:16828 (2)
CHEBI:17015 (2)
CHEBI:17154 (2)
CHEBI:17345 (2)
CHEBI:17361 (2)
CHEBI:17895 (2)
CHEBI:18211 (2)
CHEBI:18257 (2)
CHEBI:18307 (2)
CHEBI:32816 (2)
CHEBI:37024 (2)
CHEBI:7916 (2)
CHEBI:10782 (1)
CHEBI:1148 (1)
CHEBI:137246 (1)

Metabolite Name

AMP (2)
Adenine (2)
Adenosine (2)
CMP (2)
Citrulline (2)
Creatinine (2)
Hypoxanthine (2)
Inosine (2)
L-Tryptophan (2)
L-Tyrosine (2)
Oleic acid (2)
Ornithine (2)
Palmitic acid (2)
Succinic acid (2)
Xanthine (2)
(S)-(-)-Perillyl alcohol (1)
(S)-2,3,4,5-tetrahydropyridine-2-carboxylate (1)
(S)-5-Amino-3-oxohexanoate (1)
1-Aminocyclopropanecarboxylic acid (1)
1-Methylnicotinamide (1)
2,5-Dimethylbenzaldehyde (1)
2-Hydroxy-2-ethylsuccinic acid (1)
2-Hydroxybutyric acid (1)
25-Hydroxycholesterol (1)
3-(2-Hydroxyphenyl)propanoic acid (1)
3-hydroxybutyric acid (1)
4-Hydroxybenzaldehyde (1)
4-Hydroxyphenylacetaldehyde (1)
4-Pyridoxic acid (1)
4-formyl Indole (1)

First Public Date

2019 (1)

Study type

Transcription profiling by array (33)
RNA-seq of coding RNA (6)
ChIP-seq (4)
Transcription profiling by SAGE (1)
Unknown experiment type (1)

Release Date

2021 (88)
2022 (75)
2023 (72)
2024 (70)
2025 (70)
2020 (63)
2019 (55)
2018 (40)
2017 (33)
2014 (32)
2016 (29)
2015 (28)
2013 (20)
2012 (20)
2011 (20)
2008 (19)
2010 (15)
2009 (13)
2026 (5)
2007 (3)
2006 (3)
2004 (3)
2003 (1)
2005 (1)
2001 (1)
1999 (1)

Lab affiliation

Max-Planck-Institute for Biology of Ageing Department of Mitochondrial Proteostasis Joseph-Stelzmann-Str. 9b 50931 Cologne (13)
Max-Planck-Institute for Biology of Ageing Department of Mitochondrial Proteostasis Joseph-Stelzmann-Str. 9b 50931 Cologne Germany (5)
University of Cologne (4)
Institute for Biochemistry, University of Cologne (3)
Redox Metabolism, Institute for Biochemistry, University of Cologne (3)
IBC2, Goethe University Frankfurt, Germany (2)
Institute for Genetics and Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, Cologne, Germany (2)
Max-Planck-Institute for Biology of Ageing Department of Mitochondrial Proteostasis Joseph-Stelzmann-Str. 9b 50931 Cologne, Germany (2)
Max-Planck-Institute for Biology of Ageing Joseph-Stelzmann-Str. 9b 50931 Cologne, Germany (2)
Proteomics, Max Planck Institute of Biophysics, Frankfurt am Main, Germany (2)
1 Cambridge Systems Biology Centre, University of Cambridge, Cambridge, UK 2 Cambridge Centre for Proteomics, Department of Biochemistry, University of Cambridge, Cambridge, UK 3 Department of Biochemistry, University of Cambridge, Cambridge, UK (1)
1. Peripheral Neuropathy Research Group, Department of Biomedical Sciences, University of Antwerp, Antwerp, Belgium 2. Laboratory of Neuromuscular Pathology, Institute Born Bunge, Antwerp, Belgium (1)
1Seer, Inc., Redwood City, CA 94065, USA; 4Center for Nanomedicine and Department of Anesthesiology, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA 02115, USA (1)
CECAD Research Center, Institute for Genetics, University of Cologne, Joseph-Stelzmann-Str. 26, 50931 Cologne, Germany (1)
Department Langer - Mitochondrial Proteostasis Max-Planck Institut für Altersforschung Joseph-Stelzmann Str 9b 50931 Cologne, Germany (1)
Department Molecular Toxicology, Helmholtz Centre for Environmental Research GmBH - UFZ (1)
Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02215, USA., Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115, USA (1)
Department of Mitochondrial Proteostasis Joseph-Stelzmann-Str. 9b 50931 Cologne (1)
Excellence Cluster on Cellular Stress Responses in Aging Associated Diseases (CECAD) and Center for Molecular Medicine Cologne (CMMC), University of Cologne, Joseph-Stelzmann-Strasse 26, 50931 Cologne, Germany (1)
Helmholtz-Centre for Environmental Research - UFZ, Department of Molecular Toxicology (1)
Helmholtz-Centre for Environmental Research – UFZ, Department of Molecular Toxicology (1)
Institute for Clinical Chemistry and Laboratory Medicine, Vascular Biology Laboratory, University Medical Center Hamburg, Hamburg, Germany (1)
Institute for Clinical Chemistry and Laboratory Medicine, Vascular Biology Laboratory, University Medical Center Hamburg-Eppendorf, Hamburg, Germany (1)
Institute for Genetics and Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, Joseph-Stelzmann-Str. 26 50931 Cologne, Germany (1)
Institute for Genetics and Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, Joseph-Stelzmann-Strasse 26, 50931 Cologne, Germany. Center for Molecular Medicine (CMMC), University of Cologne, 50931 Cologne, Germany (1)
Institute for Genetics, Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), and University of Cologne, Cologne, Germany (1)
Institute for Genetics, University of Cologne, Cologne, Germany (1)
Institute for Immunodeficiency, Center for Chronic Immunodeficiency, Medical Center, Faculty of Medicine, Albert-Ludwigs-University of Freiburg. Breisacher Strae 115, 79106 Freiburg, Germany. (1)
Julian Langer: MPI for Biophysics and Brain Research Kate Heesom (k.heesom@bristol.ac.uk): University of Bristol Proteomics Facility (1)
MPI of Biophysics and MPI for Brain Research (1)

Tags

xref:PubMed:33021676 (1)
xref:PubMed:30717826 (1)

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Thymic epithelial organoids mediate T-cell development.

Not available

S-EPMC11441983 | biostudies-literature

AIFM1 KO and AIFM1del mutant HEK cell proteomics

Mitochondrial proteases regulate the dynamic properties of the organelle morphology and ensure functional plasticity at the cellular level. The metalloprotease OMA1 mediates constitutive and stress-inducible processing of its substrates in mitochondria, but the number of functionally characterized s...

ORGANISM(S): Homo sapiens (Human)

2026-01-31 | PXD063602 | Pride

HDX-MS analysis of IRGQ in the presence of GABARAP-L2 and LC3B

The autophagy-lysosome system directs the degradation of a wide variety of cargo and is also involved in tumor progression. Here we show that immunity-related GTPase family Q protein (IRGQ) acts in the quality control of MHC-I molecules and directs misfolded MHC-I for lysosomal degradation through i...

ORGANISM(S): Homo sapiens (Human) Escherichia coli

2024-11-26 | PXD045212 | Pride

Hdx-ms Irgq Ligand binding

Long-read DNA sequencing fully characterized chromothripsis in a patient with Langer-Giedion syndrome and Cornelia de Lange syndrome-4.

Not available

S-EPMC7324355 | biostudies-literature

Identification of a Gypsy SHOX mutation (p.A170P) in Leri-Weill dyschondrosteosis and Langer mesomelic dysplasia.

Not available

S-EPMC3230364 | biostudies-literature

Artificial Targets: a versatile cell-free platform to characterize CAR T cell function in vitro.

Not available

S-EPMC10906080 | biostudies-literature

The genomic and enzymatic basis for iridoid biosynthesis in cat thyme (Teucrium marum)

Iridoids are non-canonical monoterpenoids produced by both insects and plants. An example is the cat attracting and insect repelling volatile iridoid nepetalactone, produced by Nepeta sp. (catmint) and aphids. Recently, both nepetalactone biosynthetic pathways were elucidated, showing a remarkable c...

2026-04-20 | MTBLS9357 | MetaboLights

T cell repertoire breadth is associated with the number of acute respiratory infections in the LoewenKIDS birth cohort.

Not available

S-EPMC10258752 | biostudies-literature

Extracellular vesicles of patients with acute-on-chronic liver failure induce mitochondrial dysfunction in T cells.

Not available

S-EPMC12497775 | biostudies-literature

A new twist on bacterial motility – two distinct type IV pili revealed by cryoEM

Many bacteria express filaments called type IV pili on their surface, which are involved in motility (twitching), surface adhesion, biofilm formation and DNA uptake (natural transformation). Type IV pili are comprised of a helical assembly of repeating pilin subunits that allow both flexibility and ...

ORGANISM(S): Thermus thermophilus HB27

2020-03-09 | PXD017353 | Pride

Electron cryo-tomography Flexible filaments Type iv pili Electron cryo-microscopy Pilin

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