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ProteomicsLC-MSMS of primary HGSC class I immunopeptidom
High-grade serous ovarian cancer (HGSC), the principal cause of death from gynecological malignancies in the world, has not significantly benefited from recent progress in cancer immunotherapy. While HGSC infiltration by lymphocytes correlates with superior survival, the nature of antigens that can ...
ORGANISM(S): Homo sapiens (Human) 
2020-02-18 | PXD014062 | Pride
Lc-msms Immunopeptidome Hgsc Mhc class i 
UnknownEfficacy of mefloquine and its enantiomers in a murine model of Mycobacterium avium infection.
Not available
S-EPMC11441642 | biostudies-literature
UnknownHigh Systemic Exposure of Pyrazinoic Acid Has Limited Antituberculosis Activity in Murine and Rabbit Models of Tuberculosis.
Not available
S-EPMC4914615 | biostudies-literature
UnknownImmunopeptidomic analyses of colorectal cancers with and without microsatellite instability.
Not available
S-EPMC9134101 | biostudies-literature
UnknownIn Vivo-Selected Pyrazinoic Acid-Resistant Mycobacterium tuberculosis Strains Harbor Missense Mutations in the Aspartate Decarboxylase PanD and the Unfoldase ClpC1.
Not available
S-EPMC5514395 | biostudies-literature
ProteomicsDiscovery of tumor-specific antigens in colorectal cancer
Colorectal cancer is the second leading cause of cancer death worldwide, and the incidence of this disease is expected to increase as global socioeconomic changes occur. Immune checkpoint inhibition therapy is effective in treating a minority of colorectal cancer tumors; however, microsatellite stab...
ORGANISM(S): Homo sapiens (Human) 
2022-04-13 | PXD028309 | Pride
Lc-msms Colorectal cancer Immunopeptidome Mhc class i 
UnknownCharacteristics and outcomes of COVID-19 in hospitalized patients with and without diabetes.
Not available
S-EPMC7404605 | biostudies-literature
UnknownBreast cancer immunopeptidomes contain numerous shared tumor antigens.
Not available
S-EPMC10760959 | biostudies-literature
ProteomicsComprehensive proteogenomic analysis identifies immune targets in microsatellite stable and unstable colorectal cancers
Immunotherapy in colorectal cancer (CRC) has largely focused on microsatellite instability (MSI) tumors, based on the assumption that high mutational burden drives immunogenicity. However, most CRCs are microsatellite-stable (MSS) and remain unresponsive to checkpoint blockade. Using proteogenomic p...
ORGANISM(S): Homo sapiens (Human) 
2026-05-26 | PXD071022 | Pride
Colorectal cancer Tumor-specific antigen Mass spectrometry Cancer immunotherapy Immunopeptidomics 
ProteomicsLC-MSMS of primary breast cancer samples
CD8 T cells drive the anti-cancer immune response through the recognition of MHC I-associated peptides. In order to identify relevant targets for cancer immunotherapy in breast cancer, we characterized the immunopeptidome of 26 primary breast cancer samples from two different subtypes, hormone-recep...
ORGANISM(S): Homo sapiens (Human) 
2023-11-15 | PXD034818 | Pride
Lc-msms Breast cancer Immunopeptidome Mhc class i 
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