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ProteomicsLC-MSMS of primary HGSC class I immunopeptidom
High-grade serous ovarian cancer (HGSC), the principal cause of death from gynecological malignancies in the world, has not significantly benefited from recent progress in cancer immunotherapy. While HGSC infiltration by lymphocytes correlates with superior survival, the nature of antigens that can ...
ORGANISM(S): Homo sapiens (Human) 
2020-02-18 | PXD014062 | Pride
Lc-msms Immunopeptidome Hgsc Mhc class i 
TranscriptomicsExpression data from high-grade serous ovarian carcinomas (HGSC), clear cell ovarian carcinomas (CCC) and ovarian surface epithelium (OSE)
Background: The aim of this study was to identify differentially expressed miRNAs in high-grade serous ovarian carcinoma (HGSC), clear cell ovarian carcinoma (CCC) and ovarian surface epithelium (OSE). Selected miRNAs were evaluated for association with clinical parameters including survival, and mi...
ORGANISM(S): Homo sapiens 
2014-02-13 | E-GEOD-47841 | biostudies-arrayexpress
TranscriptomicsProfiles of genomic instability in high-grade serous ovarian cancer (HGSC) predict treatment outcome
Profiling of loss of heterozygosity (LOH) in HGSC, subcrouping HGSC by LOH-based clustering and comparing to the LOH profiles of triple-negative breast cancer [previously submitted; GSE19594]. Study for the correlation of LOH burdern and LOH-based subgroups to clinical response to platinum-based ch...
ORGANISM(S): Homo sapiens 
2012-11-06 | E-GEOD-39130 | biostudies-arrayexpress
GenomicsBCM-HGSC Rodent Genome Projects
BCM-HGSC Rodent Genome Projects
PRJNA170428 | ENA
GenomicsBCM-HGSC Marine Mammal Genome Projects
BCM-HGSC Marine Mammal Genome Projects
PRJNA170427 | ENA
GenomicsGene Expression Profiling in progesterone-induced HGSC development.
Gene Expression Profiling in progesterone-induced HGSC development.
PRJNA663551 | ENA
ProteomicsEarly fallopian tube lesions and HGSC multiomics dataset
High-grade serous cancer (HGSC) of the ovary is the most common ovarian cancer subtype, typically diagnosed at late stages with a poor prognosis. Understanding early molecular events driving HGSC progression is crucial for developing effective detection strategies. We integrated spatial cell-type re...
ORGANISM(S): Homo sapiens (Human) 
2026-09-22 | PXD062349 | Pride
Fallopian tube cancer precursors Ovarian cancer Spatial multiomics Hgsc 
ProteomicsEarly fallopian tube lesions and HGSC spatial proteomics dataset
High-grade serous carcinoma (HGSC) is the most common ovarian cancer subtype, typically diagnosed at late stages with poor prognosis. Understanding early molecular events driving HGSC progression is crucial for early-stage cancer detection and development of effective treatment stategies. We perform...
ORGANISM(S): Homo sapiens (Human) 
2026-09-29 | PXD084823 | Pride
Fallopian tube cancer precursors Ovarian cancer Spatial proteomics Hgsc Stic (serous tubal intraepithelial carcinoma) 
UnknownProteogenomic Characterization of Ovarian HGSC Implicates Mitotic Kinases, Replication Stress in Observed Chromosomal Instability.
Not available
S-EPMC7289043 | biostudies-literature
ProteomicsOvercoming intra-tumoral heterogeneity for biomarker discovery in the High-Grade Serous Ovarian Cancer proteome
High-grade serous ovarian cancer (HGSC) has a disproportionate impact on cancer-related mortality in women. There is an urgent need to improve treatment options for HGSC. This includes better selection of patients who will benefit from existing treatments, including HRD targeted therapy, and discove...
ORGANISM(S): Homo sapiens (Human) 
2025-06-13 | PXD042150 | Pride
Hgsoc Cgas-sting Heterogeneity Muti-omics Swath-ms 
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