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UnknownSynthesis and cyclic voltammetric studies of diiron complexes, ER(2)[(eta-C(5)H(4))Fe(L(2))Me](2) (E = C, Si, Ge, Sn; R = H, alkyl; L(2) = diphosphine] and (eta-C(5)H(5))Fe(L(2))ER(2)Fc [Fc = (eta-C(5)H(4))Fe(eta-C(5)H(5))].
Not available
S-EPMC2710850 | biostudies-literature
TranscriptomicsThe RpoN Regulon of Escherichia coli O157:H7
There is increasing evidence to support a role for sigma factor 54 (RpoN) in the regulation of stress resistance factors and protein secretion systems important to bacterial transmission and pathogenesis. In enterohemorrhagic E. coli O157:H7, acid resistance and type III secretion are essential det...
ORGANISM(S): Escherichia coli O157:H7 str. Sakai 
2009-08-08 | E-GEOD-17467 | biostudies-arrayexpress
MetabolomicsEnergy-stress-mediated AMPK activation inhibits ferroptosis

Energy stress depletes ATP and induces cell death. Here we identify an unexpected inhibitory role of energy stress on ferroptosis, a form of regulated cell death induced by iron-dependent lipid peroxidation. We found that ferroptotic cell death and lipid peroxidation can be inhibited by treatment...

2023-01-31 | MTBLS1399 | MetaboLights
UnknownPorphyrin-substrate binding to murine ferrochelatase: effect on the thermal stability of the enzyme.
Not available
S-EPMC1134880 | biostudies-literature
UnknownIntermonomer electron transfer between the low-potential b hemes of cytochrome bc₁.
Not available
S-EPMC3184928 | biostudies-literature
MetabolomicsGlycerol 3-phosphate phosphatase/PGPH-2 counters metabolic stress and promotes healthy aging via a glycogen sensing-AMPK-HLH-30-autophagy axis in C. elegans
Metabolic stress caused by excess nutrients accelerates aging. We recently demonstrated that the newly discovered enzyme glycerol-3-phosphate phosphatase (G3PP; gene Pgp), which operates an evolutionarily conserved glycerol shunt that hydrolyzes glucose-derived glycerol-3-phosphate to glycerol, coun...
2024-02-07 | MTBLS6847 | MetaboLights
MetabolomicsDetection of adulteration in Iranian saffron samples by 1H NMR spectroscopy and multivariate data analysis techniques
Introduction: The high market value of saffron (Crocus sativus L.) has made it an attractive candidate for adulteration. Safflower (Carthamus tinctorius L.) and tartrazine are among the most common herbal and synthetic foreign materials that may be added to pure saffron for the purpose of adulterati...
2017-07-20 | MTBLS331 | MetaboLights
ProteomicsThe Human Melanoma Proteome Atlas – Defining the Molecular Pathology & Complementing the Melanoma Transcriptome
This project is an initiative to map the protein levels in malignant melanoma tumor samples, focused on in-depth histopathology coupled to proteome characterization. The protein levels and localization from this project were determined for a broad spectrum of diverse, surgically isolated melanoma tu...
ORGANISM(S): Homo sapiens (Human) 
2021-07-16 | PXD026086 | Pride
Proteogenomics Histopathology Heterogeneity Braf Phosphorylation Driver mutations Metastatic malignant melanoma Sub-cellular localization Acetylation stoichiometry Post-translational-modification 
ProteomicsPhosphoproteomics of truncated FGFR2, a clinically actionable oncogene in multiple cancers
Somatic hotspot mutations and structural amplifications and fusions affecting fibroblast growth factor receptor 2 (FGFR2) occur in multiple cancer types. However, clinical responses to FGFR inhibitors (FGFRi) have remained variable, emphasizing a need to better understand which FGFR2 alterations are...
ORGANISM(S): Mus musculus (Mouse) 
2022-06-06 | PXD031711 | Pride
Cancer Fgfr2 Imac Mouse model Ptyrip Label-free Phosphoproteomics 
UnknownCorrection: Integrative analysis identifies an older female-linked AML patient group with better risk in ECOG-ACRIN Cancer Research Group's clinical trial E3999.
Not available
S-EPMC10322919 | biostudies-literature
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