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ProteomicsDiscovery of gastric cancer-specific biomarkers by the application of serum proteomics
The aims of this study are to compare the proteomes of serum samples from patients with gastric cancers and normal controls, and to develop useful tumor markers of gastric cancer by quantitative proteomic analysis
ORGANISM(S): Homo sapiens (Human) 
2017-02-08 | PXD005156 | Pride
Human Gastric cancer Serum Biomarker 
ProteomicsHuman HeLa cell lince SILAC
The arginylation branch of the N-end rule pathway positively regulates cellular autophagic flux and clearance of proteotoxic protein
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-03-29 | MSV000080791 | MassIVE
ProteomicsAlterations in lipid profile of the aging kidney identified by MALDI imaging mass spectrometry
During aging, the kidney undergoes functional and physiological changes that are closely affiliated with chronic kidney disease (CKD). There is increasing evidence supporting the role of lipid or lipid-derived mediators in the pathogenesis of CKD and other aging-related diseases. To understand the r...
ORGANISM(S): Mus musculus (Mouse) 
2019-06-10 | PXD013860 | Pride
Ckd Lipidomics Chronic kidney disease Ims Renal fibrosis 
TranscriptomicsmiR-431 promotes differentiation and regeneration of old skeletal muscle by targeting Smad4
we identified novel age-related microRNAs through comparative analysis of miRNA expression profiles in young and old myoblasts using next generation sequencing (NGS) small RNA profiles of young mouse and old mouse were generated by deep sequencing, in each four samples, using Illumina GAIIx
ORGANISM(S): Mus musculus 
2015-09-04 | E-GEOD-66267 | biostudies-arrayexpress
ProteomicsPGRC Cancer Proteome Study of Gastric Tissue
The goal of the project is to analyze different layers of proteome information including protein abundance and post-translational modifications of PGRC gastric tissue samples. Three pairs of human gastric cancer and adjacent normal tissues were extensively characterized by serial enrichments of phos...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-03-31 | MSV000080818 | MassIVE
ProteomicsSystematic Proteome Profiling of Maternal Plasma for Development of Preeclampsia Biomarkers
Background: Preeclampsia (PE) is a hypertensive disorder of pregnancy with various clinical symptoms. However, traditional markers for the disease including high blood pressure and proteinuria are poor indicators of the related adverse outcomes. Here, we performed systematic proteome profiling of pl...
ORGANISM(S): Homo sapiens (Human) 
2025-05-06 | PXD050118 | Pride
Proteomics Plasma Preeclampsia Human 
ProteomicsIn-Depth Platelet Proteomic Analysis in Various Dementia Stages: Unveiling Biomarkers for Alzheimer's Disease
Early detection of Alzheimer’s disease (AD) can provide an effective scheme to prevent the disease progression. Studies have shown that blood platelets are a useful peripheral source for AD diagnosis. Identifying proteomics-based platelet biomarkers of mild cognitive impairment (MCI) and AD related ...
ORGANISM(S): Homo sapiens (Human) 
2026-05-25 | PXD067460 | Pride
Alzheimer’s disease Liquid chromatography-tandem mass spectrometry  biomarker Amyloid Mild cognitive impairment Proteomics Platelets 
ProteomicsProteomic analysis of human follicular fluid in poor ovarian responders during in vitro fertilization
Poor ovarian response (POR) observed in controlled ovarian stimulation (COS) is often observed during in vitro fertilization and embryo transfer (IVF-ET) cycles and is a major problem. A POR has been found to be related to several factors, including advanced age, high body mass index, and history of...
ORGANISM(S): Homo sapiens (Human) 
2018-07-05 | PXD005436 | Pride
Multiple reaction monitoring Follicular fluid Biomarker Proteomics Poor ovarian response 
ProteomicsProteomic analysis reveals distinct metabolic differences between GM-CSF and M-CSF grown macrophages derived from murine bone marrow cells
Macrophages are crucial in controlling infectious agents and tissue homeostasis. Macrophages require a wide range of functional capabilities in order to fulfill distinct roles in our body, one being rapid and robust immune responses. To gain insight into macrophage plasticity and the key regulatory ...
ORGANISM(S): Mus musculus (Mouse) 
2015-08-04 | PXD002582 | Pride
Macrophage Phosphoproteins Tmt Protein identification Immunology Mass spectrometry 
ProteomicsVutiglabridin ameliorates obesity by directly reducing fat mass through AMPK/lipophagy activation in adipocytes
Current anti-obesity therapies that suppress appetite often cause undesirable reductions in lean mass by indirectly depleting systemic energy store. In this study, we developed a novel anti-obesity drug, Vutiglabridin (VUTI), designed to selectively reduce fat mass while preserving lean mass. We eva...
ORGANISM(S): Mus Musculus (mouse) 
2026-04-30 | PXD069901 | JPOST Repository
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