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MetabolomicsShort-term changes in the serum metabolome after laparoscopic sleeve gastrectomy and Roux-en-Y gastric bypass

INTRODUCTION: Bariatric surgery is known to be the most effective treatment for weight loss in obese patients and for the rapid remission of obesity-related comorbidities. These short-term improvements result from not only limited digestion or absorption but also dynamic changes ...

2022-03-17 | MTBLS2472 | MetaboLights
ProteomicsMouse (C57BL6/J) osteoblast LC-MS/MS
Physiological pathway of bone metabolism have been characterized well relatively. But antagonic pathway are less well studied. Here we investigated a negative regulator of osteogenesis with peroxiredoxin 5 (Prdx5) knockout mice that shows delay the bone metabolism. Prdx5-deficiency triggers a drasti...
ORGANISM(S): Mus musculus (Mouse) 
2023-02-01 | PXD020082 | Pride
Mouse Osteoblast Immunoprecipitation Prdx5 Lc-ms/ms 
ProteomicsSecretome of Acinetobacter baumannii KAB strains
We analyzed the extracellular proteome of colistin-resistant Korean Acinetobacter baumannii (KAB) strains to identify proteome profiles that can be used to characterize extensively drug-resistant KAB strains.
ORGANISM(S): Acinetobacter baumannii 
2020-05-27 | PXD015959 | Pride
Mrab Acinetobacter baumannii Secretome 
ProteomicsProteomics based analysis for associated PD-L1 in macrophage stimulated with extracellular adenosine signaling
We performed proteomics analysis to discover effector proteins for the post-transcriptional regulation of PD-L1 onhuman macrophages stimulated by adenosine signal.
ORGANISM(S): Mus musculus (Mouse) 
2022-10-14 | PXD024512 | Pride
Macrophage adenosin 
ProteomicsComprehensive proteome profiling of platelet identified a protein profile predictive of responses to an antiplatelet agent sarpogrelate.
Here, we performed a comprehensive proteome profiling of platelets collected from 18 healthy subjects before and after administration of sarpogrelate. For each subject, platelets were isolated before and then again after drug administration to investigate the alteration in the platelet proteome by s...
ORGANISM(S): Homo sapiens (Human) 
2016-09-29 | PXD003613 | Pride
Platelet proteomes Antiplatelet agents And drug responses. Lc-ms/ms 
ProteomicsComparative proteomic analysis for a putative glucose-1-phosphate thymidylyltransferase in Acidovorax citrulli
- Identification of proteins whose expression was affected by a putative glucose-1-phosphate thymidylyltransferase in Acidovorax citrulli str. KACC17005 - Shotgun proteomic analysis was used - Two strains were used with three biological replicates (total 6 samples). W: the wild-type strain. 2A: a p...
ORGANISM(S): Acidovorax citrulli 
2026-02-09 | PXD059196 | Pride
Acidovorax citrulli Glucose-1-phosphate thymidylyltransferase Lc-ms/ms 
ProteomicsComparative proteomic analysis for proteins regulated by overexpression of two DNA methyltransferases in Xanthomonas campestris pv. vesicatoria strain 85-10.
- Identification of proteins whose abundance was altered by two DNA methyltransferases (XvDMT1 and XvDMT2) in Xanthomonas campestris pv. vesicatoria strain 85-10. - Shotgun proteomic analysis was used - Three strains were used with three biological replicates (total 9 samples). W+V: the wild-type s...
ORGANISM(S): Xanthomonas campestris pv. vesicatoria str. 85-10 
2021-03-23 | PXD019554 | Pride
Lc-ms/ms Dna methyltransferases Xanthomonas campestris pv. vesicatoria 
ProteomicsComparative proteomic analysis for a putative 2, 3-bisphosphoglycerate-dependent phosphoglycerate mutase in Acidovorax citrulli
- Identification of proteins whose expression was affected by a putative 2, 3-bisphosphoglycerate-dependent phosphoglycerate mutase in Acidovorax citrulli str. KACC17005 - Shotgun proteomic analysis was used - Two strains were used with three biological replicates (total 6 samples). WT: the wild-ty...
ORGANISM(S): Acidovorax citrulli 
2022-10-24 | PXD035156 | Pride
Lc-msms Bisphosphoglycerate-dependent phosphoglycerate mutase Acidovorax citrulli 
ProteomicsPGRC Cancer Proteome Study of Gastric Tissue
The goal of the project is to analyze different layers of proteome information including protein abundance and post-translational modifications of PGRC gastric tissue samples. Three pairs of human gastric cancer and adjacent normal tissues were extensively characterized by serial enrichments of phos...
ORGANISM(S): Homo sapiens (Human) 
2016-03-18 | PXD003115 | Pride
Human Lc-msms Multi-dimenstional proteome analysis Early onset gastric cancer 
ProteomicsAn in situ ascorbate peroxidase 2-based labeling method and its application in detecting exosome proteins released from mouse proximal tubule cells under oxidative stress
Here, we developed an in situ labeling approach to identify exosome-loaded proteins, which bypasses the traditional exosome isolation steps. In this method, an engineered ascorbate peroxidase targeting to endosomes-destined exosomes was used to label proteins loaded inside exosomes released from kid...
ORGANISM(S): Mus musculus (Mouse) 
2022-08-12 | PXD025852 | Pride
Apex2 Kidney Mouse Oxidative stress Exosomes Lc-ms/ms 
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