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UnknownLiver disease-associated keratin 8 and 18 mutations modulate keratin acetylation and methylation.
Not available
S-EPMC6988862 | biostudies-literature
UnknownFluorescent indolizine derivative YI-13 detects amyloid-β monomers, dimers, and plaques in the brain of 5XFAD Alzheimer transgenic mouse model.
Not available
S-EPMC7757811 | biostudies-literature
UnknownAngiotensin II receptor I blockade prevents stenosis of tissue engineered vascular grafts.
Not available
S-EPMC6219835 | biostudies-literature
TranscriptomicsTranscription profiling of human 48 clinical breast cancer arrays to perform statistical identification of gene association by CID in application of constructing ER regulatory network
A variety of high-throughput techniques are now available for constructing comprehensive gene regulatory networks in systems biology. In this study, we report a new statistical approach for facilitating in silico inference of regulatory network structure. The new measure of association, coefficient ...
ORGANISM(S): Homo sapiens 
2009-07-19 | E-GEOD-17041 | biostudies-arrayexpress
ProteomicsCD99-mediated immunological synapse formation potentiates CAR-T cell function
Cross-talks between actin and microtubules underly various cellular processes. Using immune synapse model and via cytoskeleton dynamics analyses, here, we demonstrate that CD99 is critical for the actin and microtubule cross-talks and the coordinated reorganization, mediating their physical linkage ...
ORGANISM(S): Mus musculus (Mouse) 
2025-07-18 | PXD039955 | Pride
Immunology Cd99 
UnknownCostunolide Induces Apoptosis via the Reactive Oxygen Species and Protein Kinase B Pathway in Oral Cancer Cells.
Not available
S-EPMC8305390 | biostudies-literature
UnknownHoneysuckle Aqueous Extracts Induced let-7a Suppress EV71 Replication and Pathogenesis In Vitro and In Vivo and Is Predicted to Inhibit SARS-CoV-2.
Not available
S-EPMC7920029 | biostudies-literature
ProteomicsO-GlcNAcylation of RIPK1 Rescues Red Blood Cells from Necroptosis
Necroptosis is a type of cell death with excessive inflammation and organ damage in various human diseases. Although abnormal necroptosis is common in patients with neurodegenerative, cardiovascular, and infectious diseases, the mechanisms by which O-GlcNAcylation contributes to the regulation of ne...
ORGANISM(S): Homo sapiens (Human) 
2023-06-06 | PXD042579 | Pride
Necroptosis O-glcnac Ripk1 
ProteomicsLateral interactions between B7-H3 and CD147 are essential for stemness in breast cancer: a novel insight from proximal proteome analysis
Oncogenic cell-surface membrane proteins contribute to the phenotypic and functional characteristics of cancer stem cells (CSCs). We quantitatively analyzed cell-surface membrane proteins that are in close proximity to CD147 in CSCs using proximity-labeling proteomic approach. Moreover, we compared ...
ORGANISM(S): Homo sapiens (Human) 
2023-10-24 | PXD036909 | Pride
Proximal proteome analysis Breast cancer Cancer stem cells Drug resistance Cd276 Lipid raft Protein-protein interaction Cd147 
ProteomicsAnti-proteolytic regulation of KRAS by USP9X/NDRG3 in KRAS-driven cancer development
Cancers with activating mutations of KRAS show a high prevalence and poor prognosis but remain intractable, requiring innovative strategies to overcome the poor targetability of KRAS. Here, we report that KRAS expression was post-translationally up-regulated through the deubiquitination of KRAS prot...
ORGANISM(S): Homo sapiens (Human) 
2025-05-06 | PXD051954 | Pride
Kras protein deubiquitination  ndrg3  usp9x  pancreatic cancer 
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