Sort   by:  
 Page size 
ProteomicsHypothalamic Proteomics analysis of lipopolysaccharide (LPS)-induced depressed mice
Hypothalamic dysfunction is a key pathological factor in inflammation-associated depression. In the present study, isobaric tags for relative-absolute quantitation (iTRAQ) combined with mass spectrometry were employed to detect the proteomes in the hypothalamus of the lipopolysaccharide (LPS)-induce...
ORGANISM(S): Mus musculus (Mouse) 
2020-01-09 | PXD016040 | Pride
Depression Hypothalamus Lipopolysaccharide Itraq lc-ms/ms Brain tissue 
UnknownEffects of a comprehensive intervention on hypertension control in Chinese employees working in universities based on mixed models.
Not available
S-EPMC6914772 | biostudies-literature
TranscriptomicsGene expression profiles of nasopharyngeal carcinoma cell line HNE2 following TP53 overexpression
Recent studies have revealed that long non-coding RNAs (lncRNAs) participate in all steps of cancer initiation and progression by regulating protein coding genes at the epigenetic, transcriptional and post-transcriptional levels. LncRNAs are in turn regulated by other genes, forming a complex regula...
ORGANISM(S): Homo sapiens 
2015-05-14 | E-GEOD-60379 | biostudies-arrayexpress
ProteomicsHuman skin fibroblast proteome in healthy aging
The changes in the proteome of different human tissues with advancing age are poorly characterized. Here, we studied the proteins present in skin fibroblasts collected from 82 healthy individuals across a wide age spectrum (22 to 89 years old) who participated in the GESTALT (Genetic and Epigenetic...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2021-11-17 | MSV000088401 | MassIVE
TranscriptomicsRole of SIRT1 in diet-induced metabolic diseases
The purpose of this study is to investigate the role of SIRT1 in high-fat diet-induced liver steatosis and insulin resistance. SIRT1 is a nuclear enzyme that could remove an acetyl-group from target proteins by using NAD as co-substrate. Homologs of this protein in yeast and the roundworm C. elegans...
ORGANISM(S): Mus musculus 
2012-07-31 | E-GEOD-39778 | biostudies-arrayexpress
ProteomicsThe protein profile of mammary gland and tumors between Brca1-WT and MT miece by DIA-MS(DIA-data)
WT mammary gland(WTMG),mutant-MG(MTMG),WT breast tumors(WTBT),MTBT and MTBT-adjacent MG were collected to do data-independent acquisiton(DIA)mass to find the intrinsic factors that is associated with Brca1-deficiency induced breast cancer.
ORGANISM(S): Mus musculus (Mouse) 
2022-02-20 | PXD030328 | Pride
Breast cancer Mammary gland Mouse Brca1-deficiency Dia-ms 
ProteomicsThe protein profile of mammary gland and tumors between Brca1-WT and MT miece by DIA-MS(DDA data)
WT mammary gland(WTMG),mutant-MG(MTMG),WT breast tumors(WTBT),MTBT and MTBT-adjacent MG were collected to do data-independent acquisiton(DIA)mass to find the intrinsic factors that is associated with Brca1-deficiency induced breast cancer.
ORGANISM(S): Mus musculus (Mouse) 
2022-02-20 | PXD030355 | Pride
Breast cancer Mammary gland Mouse Brca1-deficiency Dia-ms 
MetabolomicsThe trans-omics landscape of COVID-19
The outbreak of coronavirus disease 2019 (COVID-19) is a global health emergency. Various omics results have been reported for COVID-19, but the molecular hallmarks of COVID-19, especially in those patients without comorbidities, have not been fully investigated. Here we collect blood samples from 2...
2021-10-06 | MTBLS2542 | MetaboLights
UnknownReprogramming the immunosuppressive tumor microenvironment through nanomedicine: an immunometabolism perspective.
Not available
S-EPMC11388279 | biostudies-literature
ProteomicsExploring the mechanism of action of Canmei formula against colorectal adenoma through multi-omics technique
Background: Canmei formula (CMF) is a traditional Chinese medicine compound with definite effect on the prevention and treatment of colorectal adenoma (CRA). It can prevent the transformation of intestinal inflammation to cancer. This study explored the mechanism of action of CMF in anti-CRA using ...
ORGANISM(S): Mus musculus (Mouse) 
2022-02-16 | PXD029296 | Pride
Human Colorectal adenoma Lc-ms 
Sort   by:  
 Page size