Sort   by:  
 Page size 
ProteomicsThermostable neurotoxins in processed scorpion medicinal material underlie its pharmaceutical basis in traditional Chinese medicine
Our work describes the first "map" of functionally active scorpion toxins in processed scorpion medicinal material and provides valuable information for unveiling the pharmaceutical basis for the “combat poison with poison to cure diseases” strategy in traditional Chinese medicine.
ORGANISM(S): Mesobuthus Martensii 
PXD012392 |
ProteomicsMass spectrometry-based direct detection of multiple types of protein thiol modifications in pancreatic beta cells under endoplasmic reticulum stress
A 2D-LC-MS/MS strategy coupled with TMT-10 labeling was applied to mouse pancreatic beta cells (hetaTC-6) induced with ER stress by Thapsigargin to study the global proteome and protein cysteine PTM changes under ER stress. Samples were digested with trypsin, labeled with 10-plex TMT, then analyzed ...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2021-05-29 | MSV000087543 | MassIVE
ProteomicsAn Integrative SP3 Workflow for Multi-PTM Proteomics Profiling
Global proteomic, redox proteomic, and phosphoproteomic data from mouse C10 epithelial cells and skeletal muscle tissue, no treatments used for method development experiments using these biological sytems. Global proteomic, redox proteomic, phosphoproteomic, and acetylomic data from mouse Beta-TC-6 ...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2024-07-06 | MSV000095264 | MassIVE
ProteomicsCyanobacterial circadian regulation enhances bioproduction under subjective nighttime through rewiring of carbon partitioning dynamics, redox balance orchestration, and cell cycle modulation
GC-MS extracellular metabolite profiling of circadian clock regulation impacts of carbon partitioning between storage, growth, and product synthesis in Synechococcus elongatus PCC 7942 for enhanced bioproduction strategy investigation. Metabolomic targeted analysis of PCC 7942 light-dark cycle cultu...
ORGANISM(S): Synechococcus Elongatus Pcc 7942 (ncbitaxon:1140) 
2024-12-21 | MSV000096722 | MassIVE
TranscriptomicsExpression data from Saccharomyces cerevisiae treated with Small Molecule Enhancers of Rapamycin (SMERs)
The target of rapamycin (TOR) plays a central role in eukaryotic cell growth control. With prevalent hyper-activation of the mTOR pathway in human cancers, novel strategies to enhance TOR pathway inhibition are highly desirable. We used a yeast-based high-throughput chemical genetic screen to identi...
ORGANISM(S): Saccharomyces cerevisiae 
2010-07-29 | E-GEOD-22269 | biostudies-arrayexpress
TranscriptomicsExpression data from Saccharomyces cerevisiae Met30 temperature-sensitive strain
The target of rapamycin (TOR) plays a central role in eukaryotic cell growth control. With prevalent hyper-activation of the mTOR pathway in human cancers, novel strategies to enhance TOR pathway inhibition are highly desirable. We used a yeast-based high-throughput chemical genetic screen to identi...
ORGANISM(S): Saccharomyces cerevisiae 
2011-06-30 | E-GEOD-22270 | biostudies-arrayexpress
TranscriptomicsExpression data from Saccharomyces cerevisiae temperature-sensitive strains specific for SCF core components (Skp1, Cullin (Cdc53), E2 enzyme (Cdc34)) and the F-box protein Cdc4.
The target of rapamycin (TOR) plays a central role in eukaryotic cell growth control. With prevalent hyper-activation of the mTOR pathway in human cancers, novel strategies to enhance TOR pathway inhibition are highly desirable. We used a yeast-based high-throughput chemical genetic screen to identi...
ORGANISM(S): Saccharomyces cerevisiae 
2011-06-30 | E-GEOD-22271 | biostudies-arrayexpress
Proteomicshydroxyproline-containing proteins of rice
Identification of hydroxyproline-containing proteins and hydroxylation of proline in rice
ORGANISM(S): Oryza Sativa 
PXD017798 |
TranscriptomicsMicroRNA Directly Enhances Mitochondrial Translation during Muscle Differentiation.
MicroRNAs are well known to mediate translational repression and mRNA degradation in the cytoplasm. Various microRNAs have also been detected in membrane-compartmentalized organelles, but the functional significance has remained elusive. Here we report that miR-1, a microRNA specifically induced dur...
ORGANISM(S): Mus musculus 
2014-08-01 | E-GEOD-57596 | biostudies-arrayexpress
ProteomicsProteomic study of SOAT1 protein targeting compounds in the treatment of liver cancer
Proteomic study of SOAT1 protein targeting compounds in the treatment of liver cancer
ORGANISM(S): Homo Sapiens 
2022-01-11 | PXD030873 |
Sort   by:  
 Page size