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UnknownEffects of Rumen-Protected Methionine on Meat Quality, Fatty Acid Composition, Volatile Flavor Compounds and Transcriptomics of <i>Longissimus lumborum</i> of Yak (<i>Bos grunniens</i>).
Not available
S-EPMC12191923 | biostudies-literature
UnknownIGF2BP2 Drives Thyroid Cancer Dedifferentiation Through m6A-Dependent STAT1 mRNA Destabilization.
Not available
S-EPMC12780945 | biostudies-literature
UnknownIcariin displays anticancer activity against human esophageal cancer cells via regulating endoplasmic reticulum stress-mediated apoptotic signaling.
Not available
S-EPMC4759694 | biostudies-literature
ProteomicsMouse cornea,sclera,skin LC-MSMS
We generated a P4ha2 knock-out mouse line (C57BL/6) by using CRISPR-Cas9 system. By mass spectrum, reduced proline hydroxylation was observed in collagens isolated from skin, sclera and cornea of P4ha2-/- mice.
ORGANISM(S): Mus musculus (Mouse) 
2026-03-02 | PXD023006 | Pride
Skin lc-msms Mouse cornea Sclera 
ProteomicsVitamin D enhances the therapeutic effect of TNF-α antibody by lipid metabolism in overweight IBD
The colonic mucosal proteins from HFD and HFD+PAL treated mice were lysed using RIPA buffer, and protein concentration was quantified by BCA assay.
ORGANISM(S): Homo Sapiens 
PXD056116 |
UnknownAcetylation of TIR domains in the TLR4-Mal-MyD88 complex regulates immune responses in sepsis
Not available
S-SCDT-10_1038-S44318-024-00237-8 | biostudies-other
ProteomicsQuantitative proteomics revealed novel protein biomarkers to distinguish malignant pleural effusion from benign pleural effusion
A four-dimensional independent data acquisition (4D-DIA) proteomic was performed to determine the differentially expressed proteins in pleural effusion samples collected from ung adenocarcinoma MPE, BPE (tuberculosis pleural effusion (TPE) and parapneumonic effusion (PPE)).
ORGANISM(S): Proteinus 
2024-03-08 | PXD050477 |
MetabolomicsAberrant gut microbiota alters host metabolome and impacts renal failure in humans and rodents

OBJECTIVE: Patients with renal failure suffer from symptoms caused by uraemic toxins, possibly of gut microbial origin, as deduced from studies in animals. The aim of the study is to characterise relationships between the intestinal microbiome composition, uraemic toxins and rena...

2020-10-20 | MTBLS700 | MetaboLights
ProteomicsDiscovery of Itaconate-Mediated Lysine Acylation
Itaconate is an important anti-microbial and immunoregulatory metabolite involved in host-pathogen interactions. A key mechanistic action of itaconate is through the covalent modification of cysteine residues via Michael addition, resulting in “itaconation”. However, it is unclear whether itaconate ...
ORGANISM(S): Mus Musculus 
2023-02-28 | PXD040508 |
ProteomicsExploring the Anti-Cancer mechanism of Cardiac Glycosides using proteome integral solubility alteration approach
Cancer remains a significant global health challenge, necessitating the development of innovative and cost-effective treatments. Drug repurposing, particularly of cardiac glycosides (CGs), offers a promising strategy to expedite the discovery of anti-tumor drugs. This study employs proteome integral...
ORGANISM(S): Homo Sapiens 
PXD052740 |
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