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ProteomicsThe role of DENND10 in neuronal development
Neuron development requires an elaborate network of endosomal transport pathways, defects in which underlie multiple neurological diseases. DENND10/FAM45A is an ancient protein that is important for endosomal homeostasis. However, the role of DENND10 in the nervous system remained unknown. Here, we ...
ORGANISM(S): Mus musculus (Mouse) 
2025-03-06 | PXD038623 | Pride
Neuron Neurite outgrowth Dennd10 Cad 
ProteomicsThe role of endosomal protein DENND10/FAM45A in extracellular vesicle release and cancer cell migration
Cell migration is key to tumor metastasis, the most challenging clinical problem in cancer treatment. Here we are investigating the role of DENND10/FAM45A, a recently described endosomal protein, in cancer cell migration via modulating the release of extracellular vesicles (EVs). Bioinformatics data...
ORGANISM(S): Mus musculus (Mouse) 
2024-06-14 | PXD038264 | Pride
Extracellular vesicle Mouse Dennd10 Mammary cancer 4t1 
UnknownEffects of Rumen-Protected Methionine on Meat Quality, Fatty Acid Composition, Volatile Flavor Compounds and Transcriptomics of <i>Longissimus lumborum</i> of Yak (<i>Bos grunniens</i>).
Not available
S-EPMC12191923 | biostudies-literature
ProteomicsThe Quantitative Proteomics Analysis Reveals the Effect of a MarR Family Transcriptional Regulator AHA_2124 on Aeromonas hydrophila
Transcription regulatory factors of MarR family play an important role in diverse bacterial physiologic functions, whereas the effect and its intrinsic regulatory mechanism on aquatic pathogenic bacteria Aeromonas hydrophila are still largely unknown. In this study, we firstly constructed a deletion...
ORGANISM(S): Aeromonas Hydrophila Subsp. Hydrophila Atcc 7966 
2023-11-02 | PXD046625 |
UnknownIGF2BP2 Drives Thyroid Cancer Dedifferentiation Through m6A-Dependent STAT1 mRNA Destabilization.
Not available
S-EPMC12780945 | biostudies-literature
UnknownIcariin displays anticancer activity against human esophageal cancer cells via regulating endoplasmic reticulum stress-mediated apoptotic signaling.
Not available
S-EPMC4759694 | biostudies-literature
ProteomicsMetabolic Glycan Labelling or not (MGL/non-MGL) A375 cell derived extracellular vesicles (EVs) Proteomics data file for comparing the difference of EV proteins before and after MGL
This project including the results of protein identification file and six samples’ Raw file that were non-processed
ORGANISM(S): Homo sapiens (Human) 
2023-10-04 | PXD045742 | Pride
Evs Proteomics 
ProteomicsMouse cornea,sclera,skin LC-MSMS
We generated a P4ha2 knock-out mouse line (C57BL/6) by using CRISPR-Cas9 system. By mass spectrum, reduced proline hydroxylation was observed in collagens isolated from skin, sclera and cornea of P4ha2-/- mice.
ORGANISM(S): Mus musculus (Mouse) 
2026-03-02 | PXD023006 | Pride
Skin lc-msms Mouse cornea Sclera 
ProteomicsVitamin D enhances the therapeutic effect of TNF-α antibody by lipid metabolism in overweight IBD
The colonic mucosal proteins from HFD and HFD+PAL treated mice were lysed using RIPA buffer, and protein concentration was quantified by BCA assay.
ORGANISM(S): Homo Sapiens 
2024-09-22 | PXD056116 |
UnknownAcetylation of TIR domains in the TLR4-Mal-MyD88 complex regulates immune responses in sepsis
Not available
S-SCDT-10_1038-S44318-024-00237-8 | biostudies-other
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