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UnknownEfficacy and Tolerability of First-Line Cetuximab Plus Leucovorin, Fluorouracil, and Oxaliplatin (FOLFOX-4) Versus FOLFOX-4 in Patients With RAS Wild-Type Metastatic Colorectal Cancer: The Open-Label, Randomized, Phase III TAILOR Trial.
Not available
S-EPMC6324088 | biostudies-literature
ProteomicsTreachery of hepatic protector triggers Notch signaling to promote hepatocyte-originated cholangiocarcinoma
Here, we found mesencephalic astrocyte-derived neurotrophic factor (MANF), a hepatic protector, was upregulated in human ICC tissues and sleeping beauty transposon (SBT) or thioacetamide (TAA)-induced mice ICC tissues. We verified the oncogenic role of MANF in ICC using cell lines overexpressing/kno...
ORGANISM(S): Homo sapiens (Human) 
2025-08-25 | PXD048451 | Pride
Hepatocytes Ip-ms Hucct1 Notch Cholangiocarcinoma Ck19 
UnknownGut microbiota-derived metabolite isovalerylcarnitine modulates salt sensitivity of blood pressure and incident hypertension: a multicenter dietary salt intervention trial.
Not available
S-EPMC12824221 | biostudies-literature
ProteomicsAlterations of protein S-glutathionylation modification in macrophages under oxidative conditions
S-glutathionylation is an important regulatory posttranslational modification of protein cysteine (Cys) thiols, yet the role of specific cysteine residues as targets of modification is poorly understood. To identify the specific molecular targets and pathways of Grx1 that are susceptible to redox-de...
ORGANISM(S): Mus musculus (Mouse) 
2021-11-01 | PXD027965 | Pride
Bmdm S-glutathionylation Lc–ms/ms 
ProteomicsImmune surveillance on the insect body surface recognizes a pathogen‑derived fungal protease to activate defenses
This project comprises two independent mass spectrometry datasets generated as part of the study “Immune surveillance on the insect body surface recognizes a pathogen‑derived fungal protease to activate defenses
ORGANISM(S): Locusta Migratoria Manilensis 
2026-03-24 | PXD076064 |
ProteomicsBartonella VBNC formation and resuscitation
DIA proteomic analysis of temp induced VBNC Bartonella henselae
ORGANISM(S): Bartonella Henselae Str. Houston-1 
2024-08-27 | PXD055316 |
UnknownGenome-wide association study in Chinese identifies novel loci for blood pressure and hypertension.
Not available
S-EPMC4303798 | biostudies-literature
UnknownGenome-wide association study in Han Chinese identifies four new susceptibility loci for coronary artery disease.
Not available
S-EPMC3927410 | biostudies-literature
ProteomicsProteomic study of exfoliation syndrome
We provided a comprehensive plasma proteome analysis and expanded the profile of human plasma proteome. The differential plasma proteomic analysis of age-related cataract and exfoliation syndrome with/without glaucoma indicated that plasma proteome can reflect the pathophysiological situation of dis...
ORGANISM(S): Homo Sapiens 
2025-03-17 | PXD061945 |
ProteomicsPRMT3 reverses HIV-1 latency by increasing chromatin accessibility to form a TEAD4-P-TEFb-containing transcriptional hub
A major challenge to the current efforts to cure HIV-1 infection is the persistence of latent viruses. Addressing this challenge hinges on unraveling the intricate interplay between the host and viral factors that are key for HIV-1 latency. Current antiretroviral agents effectively prevent actively ...
ORGANISM(S): Homo Sapiens 
2025-03-25 | PXD062187 |
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