Sort   by:  
 Page size 
ProteomicsER-associated degradation of Eag1 potassium channels by the RING E3 ubiquitin ligase MKRN1: the presence of a dual ubiquitination system
Mutations in the human gene encoding the neuron-specific Eag1 voltage-gated K+ channel are associated with neurodevelopmental diseases, indicating an important role of Eag1 during brain development. A disease-causing Eag1 mutant channel is linked to defective protein stability that involves enhanced...
ORGANISM(S): Homo sapiens (Human) 
2021-09-10 | PXD023984 | Pride
Ring e3 Mkrn1 
ProteomicsStomatin modulates adipogenesis through ERK pathway and regulates fatty acid uptake and lipid droplet growth
Controlling fatty acid uptake, lipid production and storage, and metabolism of lipid droplets (LDs), is closely related to lipid homeostasis, adipocyte hypertrophy and obesity. We report here that stomatin, a major constituent of lipid rafts, participates in adipogenesis and adipocyte maturation by ...
ORGANISM(S): Mus musculus (Mouse) 
2022-07-05 | PXD031866 | Pride
Erk pathway Adipogenesis 3t3-l1 adipocyte-like cell 
ProteomicsActivation of Akt, Nrf2, and NF-κB signal transduction pathways in the liver as a mechanism of survival for torpid Myotis ricketti Bats
Unfolded protein accumulation in the lumen of endoplasmic reticulum (ER) induced by cold exposure is termed UPRER. Some mammals hibernate to overcome cold winter. We investigated whether hibernating bats are under UPRER and activate Akt, Nrf2, and NF-κB signaling pathways that are critical for cell ...
ORGANISM(S): Myotis ricketti 
2020-11-17 | PXD016109 | Pride
Mitochondria Eif2 Akt Hibernation Upr And lc-ms/ms Nf-κb Bats Proteomics Liver 
ProteomicsMaintenance of Neural Activities in Torpid Rhinolophus ferrumequinum Bats Revealed by 2D Gel-based Proteome Analysis
Bats are the only mammals capable of self-powered flying. Many bat species hibernate in winter. A reversible control of cerebral activities is critical for bats to accommodate a repeated torpor-arousal cycle during hibernation. Little is known about the molecular mechanism that regulates neuronal ac...
ORGANISM(S): Bos taurus (Bovine) Pan troglodytes (Chimpanzee) Rattus rattus (Black rat) Arabidopsis thaliana (Mouse-ear cress) Mesocricetus auratus (Golden hamster) Homo sapiens (Human) Mus musculus (Mouse) Sus scrofa domesticus (domestic pig) Rattus norvegicus (Rat) Equus caballus (Horse) 
2017-05-11 | PXD005158 | Pride
Gnao1 Hibernation Palmitoylation Bats Lc-ms/ms 
ProteomicsPlasma Proteomic Changes of Atherosclerosis After Exercise in ApoE knockout Mice
Atherosclerosis is the preliminary cause of coronary artery disease, one of the diseases that ac-count for the largest number of fatal mortalities. Physical activity is an effective strategy to restrain atherosclerosis from deterioration. Evidence indicated that the changes of proteomic profile is h...
ORGANISM(S): Mus musculus (Mouse) 
2022-04-04 | PXD030951 | Pride
Atherosclerosis  complement factor c5  exercise  proteomic changes  chemotaxis 
ProteomicsEffects of Caloric Restriction with Protein Supplementation on Plasma Protein Profiles in Middle-Aged Women with Metabolic Syndrome – A Preliminary Open Study
Clinical studies have demonstrated that higher protein intake based on caloric restriction (CR) alleviates metabolic abnormalities. However, no study has examined the effects of plasma protein profiles on caloric restriction with protein supplementation (CRPS) in metabolic syndrome (MetS). Therefore...
ORGANISM(S): Homo sapiens (Human) 
2019-11-13 | PXD012213 | Pride
Metabolic syndrome  caloric restriction  protein supplementation  plasma proteomics 
ProteomicsComparative O-GlcNAc Proteomic Analysis Reveals a Role of O-GlcNAcylated SAM68 in Lung Cancer Aggressiveness
O-GlcNAcylation is a reversible and dynamic post-translational protein modification catalyzed by O-GlcNAc transferase (OGT). Despite the reported association of O-GlcNAcylation with cancer metastasis, the O-GlcNAc proteome profile for cancer aggressiveness remains largely uncharac-terized. Here we r...
ORGANISM(S): Homo sapiens (Human) 
2022-02-17 | PXD029627 | Pride
Lung adenocarcinoma  o-glcnac transferase  o-glcnacylation  sam68 
TranscriptomicsRNA-seq of Leptospirillum ferriphilum DSM 14647 cells treated with quorum sensing signal compounds
Differential gene expression analysis of Leptospirillum ferriphilum DSM 14647 cells treated with quorum sensing singnal compounds. Briefly, Leptospirillum ferriphilum DSM 14647 cells were grown to early stationary phase in Mackintosh basal salt solution (Mac medium) pH 1.8 (Mackintosh 1978) with 71....
ORGANISM(S): Leptospirillum ferriphilum DSM 14647 
2021-03-01 | E-MTAB-9845 | biostudies-arrayexpress
UnknownSequencing and comparative genomic analysis of pK29, a 269-kilobase conjugative plasmid encoding CMY-8 and CTX-M-3 beta-lactamases in Klebsiella pneumoniae.
Not available
S-EPMC1932545 | biostudies-literature
ProteomicsProteomic study of localized tissue necrosis by Naja atra venom
Naja atra bites frequently cause immediate and serious disease. N. atra venom contains a complex of toxic components that can cause immediate and direct harm to the patient's skin tissue. If not treated effectively, it can readily progress to widespread localized necrosis, which in severe cases may ...
ORGANISM(S): Sus scrofa domesticus (domestic pig) 
2024-07-03 | PXD052498 | Pride
Naja atra venom proteomics parallel reaction monitoring snakebite 
Sort   by:  
 Page size