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UnknownPyroptotic cell corpses are crowned with F-actin-rich filopodia that engage CLEC9A signaling in incoming dendritic cells.
Not available
S-EPMC11695261 | biostudies-literature
UnknownNicotine promotes neuron survival and partially protects from Parkinson's disease by suppressing SIRT6.
Not available
S-EPMC6223043 | biostudies-literature
ProteomicsA new life-saving role for Glucocorticoid Receptor dimers: repressing STAT1-induced IFN response in the gut
The use of glucocorticoids (GCs), which bind and activate the glucocorticoid receptor (GR), in systemic inflammatory response syndromes (SIRS) is disputed. Mice with a poor transcriptional response of dimer-dependent GR target genes were studied in a model of TNF-induced SIRS. These GR dim/dim mice ...
ORGANISM(S): Mus musculus (Mouse) 
2019-04-01 | PXD008608 | Pride
Isg Inflammatory response Murine ileum Sirs Shotgun proteomics 
TranscriptomicsMethylome analysis of congenital ectopic thyroids
To assess whether specific genes have relevant somatic genetic or epigenetic alterations in ectopic tissue, we used a combined analysis of transcriptome (confirmed by qRT-PCR on 68 genes), methylome, structural genome variations (copy number variants, CNVs) and miRNA profile of ectopic compared with...
ORGANISM(S): Homo sapiens 
2010-10-27 | E-GEOD-17581 | biostudies-arrayexpress
TranscriptomicsSomatic CNV profile of congenital ectopic thyroids
To assess whether specific genes have relevant somatic genetic or epigenetic alterations in ectopic tissue, we used a combined analysis of transcriptome (confirmed by qRT-PCR on 68 genes), methylome, structural genome variations (copy number variants, CNVs) and miRNA profile of ectopic compared with...
ORGANISM(S): Homo sapiens 
2010-10-27 | E-GEOD-17463 | biostudies-arrayexpress
TranscriptomicsAnalysis of transcriptome in ectopic versus orthotopic thyroid tissue.
Congenital hypothyroidism from thyroid dysgenesis (CHTD) is a sporadic disease characterized by defects in the differentiation, migration or growth of thyroid tissue. Of these defects, incomplete migration resulting in ectopic thyroid tissue is the most common (up to 80%). We obtained flashfrozen sa...
ORGANISM(S): Homo sapiens 
2010-10-28 | E-GEOD-16804 | biostudies-arrayexpress
TranscriptomicsIdentification of Lgr5-independent spheroid-generating progenitors of the mouse fetal intestinal epithelium
Immortal spheroids were generated from fetal mouse intestine using the culture system developed to culture organoids from adult intestinal epithelium. Spheroids are made of a monostratified polarized epithelium displaying a poorly differentiated intestinal phenotype. The proportion of spheroids gene...
ORGANISM(S): Mus musculus 
2014-01-21 | E-GEOD-49803 | biostudies-arrayexpress
UnknownCrosstalk interactions between transcription factors ERRα and PPARα assist PPARα-mediated gene expression.
Not available
S-EPMC11059514 | biostudies-literature
UnknownDiscrimination of three genetically close Aspergillus species by using high resolution melting analysis applied to indoor air as case study.
Not available
S-EPMC5381056 | biostudies-literature
UnknownComparative Analysis of Hepatic Gene Expression Profiles in Murine and Porcine Sepsis Models.
Not available
S-EPMC11507144 | biostudies-literature
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