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TranscriptomicsmiRNA Profile in Three Different Normal Human Ocular Tissues by miRNA-Seq
Since microRNAs (miRNAs) have been associated with eye diseases, our study aims to profile ocular miRNA expression in normal human eye tissue using miRNA-Seq in order to provide a foundation for future disease research. Total RNAs were extracted from normal human ciliary body (CB) (n=7), cornea (n=7...
ORGANISM(S): Homo sapiens 
2016-08-01 | E-GEOD-81254 | biostudies-arrayexpress
UnknownComplete Surgical Excision Is Essential for the Management of Patients With Breast Implant-Associated Anaplastic Large-Cell Lymphoma.
Not available
S-EPMC4872006 | biostudies-literature
UnknownTranslational Breast Cancer Research Consortium (TBCRC) 022: A Phase II Trial of Neratinib for Patients With Human Epidermal Growth Factor Receptor 2-Positive Breast Cancer and Brain Metastases.
Not available
S-EPMC5070554 | biostudies-literature
MetabolomicsA multi-omic analysis of birthweight in newborn cord blood reveals new underlying mechanisms related to cholesterol metabolism

BACKGROUND: Birthweight reflects in utero exposures and later health evolution. Despite existing studies employing high-dimensional molecular measurements, the understanding of underlying mechanisms of birthweight remains limited.

METHODS: To investigate th...

2020-06-19 | MTBLS1684 | MetaboLights
UnknownIdentification of a 24-gene prognostic signature that improves the European LeukemiaNet risk classification of acute myeloid leukemia: an international collaborative study.
Not available
S-EPMC3595425 | biostudies-literature
MetabolomicsMaHPIC Experiment HuC - Metabolomics of plasma samples from human volunteers infected with Plasmodium vivax
Project Description:
The Malaria Host-Pathogen Interaction Center (MaHPIC) is a transdisciplinary malaria systems biology research program initially supported by an NIH/NIAID contract (HHSN272201200031C, 2012-2017; see http://w...
2018-06-19 | MTBLS665 | MetaboLights
TranscriptomicsTranscriptome profiling of Arabidopsis using strand-specific RNA-seq
We applied single-end strand-specific RNA-seq experiments to compare the abundance of natural antisense transcripts in Arabidopsis. Examination of 3 wild type (WT) organs, including leaves, inflorescences and siliques.
ORGANISM(S): Arabidopsis thaliana 
2013-12-23 | E-GEOD-49950 | biostudies-arrayexpress
ProteomicsLigand-dependent spatiotemporal signaling profiles of the mu-opioid receptor are controlled by distinct protein-protein interaction networks
Ligand-dependent differences in the regulation and internalization of the mu-opioid receptor (MOR) have been linked to the degree of severity of the side effects that limit the use of opiates in the treatment of pain. For example, activation of the MOR by morphine and DAMGO ([D-Ala2,N-MePhe4,Gly-ol]...
ORGANISM(S): Homo sapiens (Human) 
2019-09-26 | PXD013328 | Pride
Proteomics Ras‐related c3 botulinum toxin substrate 1 (rac1) Extracellular signal regulated kinase (erk) Desmosome G protein-coupled receptor (gpcr) Cell compartmentalization Protein complex Opioid 
TranscriptomicsKRAS-Dependent Sorting of miRNAs and other small RNAs to secreted vesicles
Although long thought to act cell autonomously, mutant KRAS colorectal cancer (CRC) cells release protein-laden exosomes that can alter the tumor microenvironment. We have previously shown that mutant KRAS induces EGFR-ligand trafficking to exosomes and drastically alters exosomal protein contents,...
ORGANISM(S): Homo sapiens 
2015-08-28 | E-GEOD-67004 | biostudies-arrayexpress
TranscriptomicsPeri-alloHCT IL-33 administration expands recipient T regulatory cells that protect mice against acute GvHD
Graft-versus-Host Disease (GvH) is the excessive inflammatory response by mature T cells contained in the graft during bone marrow transplantation. The allogeneic T cells recognize self-antigens as foreign and systemically attack multiple organs mostly with epithelial structures such as the skin, li...
ORGANISM(S): Mus musculus 
2016-06-27 | E-MTAB-4677 | biostudies-arrayexpress
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