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MetabolomicsThe Genome of Medicinal Plant Macleaya cordata Provides New Insights into Benzylisoquinoline Alkaloids Metabolism
The overuse of antibiotics in animal agriculture and medicine has caused a series of potential threats to public health. Macleaya cordata is a medicinal plant species from the Papaveraceae family, providing a safe resource for the manufacture of antimicrobial feed additive for livestock. The active ...
2017-04-24 | MTBLS435 | MetaboLights
ProteomicsDNA-Protein Crosslinking Problem in Saccharomyces cerevisiae for methanol utilization
Formaldehyde-induced DNA-protein crosslinkings (DPCs) and large repeated DNA fragments suggest strategies for methanol detoxification and phenotype enhancement
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2026-01-07 | PXD064258 | Pride
Lc-ms Saccharomyces cerevisiae Methanol Dna-protein crosslinking 
ProteomicsDNA-Protein Crosslinking Problem in Saccharomyces cerevisiae for methanol utilization
Formaldehyde-induced DNA-protein crosslinkings (DPCs) and large repeated DNA fragments suggest strategies for methanol detoxification and phenotype enhancement
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2026-01-07 | PXD064984 | Pride
Lc-ms Saccharomyces cerevisiae Methanol Dna-protein crosslinking 
ProteomicsProteomics and metabolomics reveal the energy metabolism as a vital response to acupuncture treatment of migraine and the mechanism of disease
Proteomic and metabolomic characterization of migraine patient plasma with acupuncture intervention
ORGANISM(S): Homo Sapiens 
2022-09-21 | PXD028441 |
ProteomicsO-GlcNAcylation elevates topoisomerase IIα catalytic activity: a role in the chemotherapy resistance of breast cancer
DNA topoisomerase IIα (TOP2A) plays a vital role in replication and cell division by catalytically altering DNA topology. It is a prominent target for anticancer drugs. However, it is currently unknown whether TOP2A is O-GlcNAc-modified, and the mechanism by which interplay between TOP2A and O-GlcNA...
ORGANISM(S): Homo Sapiens 
PXD041284 |
ProteomicsFOXA1 O-GlcNAcylation-mediated transcriptional switch governs metastasis capacity in breast cancer
The forkhead protein FOXA1 has been found to play a critical role in orchestrating hormonal-signaling network and to function as a pioneer factor to regulate breast-specific gene expression,However, whether interplay between O-GlcNAcylation and FOXA1 affects the genome-wide transcriptional activity ...
ORGANISM(S): Homo Sapiens 
2022-12-21 | PXD039019 |
ProteomicsChromatin-associated OGT promotes hepatocellular carcinoma malignancy via activating ZNF263
OGT, the only facilitator which attaches the monosaccharide to many oncogenic factors or tumor suppressors, has been suggested to play an influential role in tumorigenesis and metastasis of HCC. OGT interactome analyses indicates that disordered OGT may serve as a hub protein to activate the buildin...
ORGANISM(S): Homo Sapiens 
2023-01-12 | PXD039365 |
ProteomicsProteomic analysis of the four rat models of depression
Major depressive disorder (MDD) is a highly heterogeneous psychiatric disorder. The pathogenesis of MDD remained unclear, and it may be associated with exposure to different stressors. Most previous studies have focused on molecular changes in a single stress-induced depression model, which limited ...
ORGANISM(S): Rattus Norvegicus 
PXD043285 |
UnknownSelection criteria for large core trials: rationale for the ANGEL-ASPECT study design.
Not available
S-EPMC8785010 | biostudies-literature
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