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ProteomicsFood perception liver phosphoproteome induced by caged food and POMC neuron activation
Liver mitochondria play a central role in metabolic adaptations to changing nutritional states, yet their dynamic regulation upon anticipated changes in energy state has remained unaddressed. Here, we show that sensory food perception rapidly induces mitochondrial fission in the liver via protein ki...
ORGANISM(S): Mus musculus (Mouse) 
2024-03-28 | PXD044227 | Pride
Pomc Food perception Liver Lc-ms/ms 
MetabolomicsRegional HNSCC metabolomics reveals widespread changes to one-carbon metabolism and S-adenosylmethionine metabolism across tumour core, tumour edge and adjacent non-tumour tissues

Cancer, including head and neck squamous cell carcinoma (HNSCC), induces changes to metabolism that drive the disease. Regional metabolomics can help to understand metabolic variation across the tumour including changes near the tumour core, where hypoxia is likely more pronounced. We apply ultra...

2026-06-03 | MTBLS1905 | MetaboLights
UnknownSelfish bacteria are active throughout the water column of the ocean.
Not available
S-EPMC9899235 | biostudies-literature
ProteomicsQuantitative proteomic dataset of the moss Physcomitrium patens SMG1 KO mutant line
Here, we provide an isobaric tag for relative and absolute quantitation (iTRAQ)-based quantitative proteomic dataset of the moss Physcomitrium patens smg1 knockout line. The kinase SMG1 is one of the key components of the NMD system in many organisms, including plants. Several lines with a deleted...
ORGANISM(S): Physcomitrella patens subsp. patens (Moss) 
2021-11-02 | PXD029205 | Pride
Nmd Physcomitrium patens Itraq 
ProteomicsChemoselective Characterization of New Extracellular Matrix Deposition in Bioengineered Tumor Tissues
Investigating ECM-regulated new ECM production has been challenging due to the proteomic background from the pre-existing biomaterial ECM. To address this issue the newly synthesized ECM proteins (newsECM) of two different bioengineered tumor models were analyzed: tumor tissues, built upon decellula...
ORGANISM(S): Homo sapiens (Human) Rattus norvegicus (Rat) 
2025-08-30 | PXD061871 | Pride
Chemoselective chemistry Newly-synthesized extracellular matrix Biomaterial Proteomics 
TranscriptomicsTranscription profiling of Medicago truncatula Mt TTG1 mutant seed
Medicago truncatula Tnt-1 insertional mutant for MtTTG1 gene (NF977) versus the wild-type R108. The seed samples are harvested at 16 days after pollination. Their transcript profiles were compared.
ORGANISM(S): Medicago truncatula 
2009-08-14 | E-MEXP-1757 | biostudies-arrayexpress
ProteomicsMetaNetwork Enhances Biological Insights from Quantitative Proteomics Differences by Combining Clustering and Enrichment Analyses
Interpreting proteomics data remains challenging due to the large number of proteins that are quantified by modern mass spectrometry methods. Weighted gene correlation network analysis (WGCNA) can identify groups of biologically related proteins using only protein intensity values by constructing pr...
ORGANISM(S): Homo sapiens (Human) 
2022-01-27 | PXD030784 | Pride
Cancer Analysis Proteomics Prostate Network Human 
ProteomicsIdentifying lncRNA-protein interactions in hematopoietic progenitor cells by hybridization capture and mass spectrometry
Long non-coding RNAs (lncRNAs) exert regulatory functions in a wide spectrum of biological contexts, and certain regulatory functions involve the formation of RNA-protein complexes. Discovering the structure/function of these complexes may unveil important functional insights. The DDX41 gene encodin...
ORGANISM(S): Mus musculus (Mouse) 
2025-07-17 | PXD062695 | Pride
Lncrna  lncrna-protein interaction  hematopoiesis  mass spectrometry  proteomics  hybridization capturelncrna  lncrna-protein interaction  hematopoiesis  mass spectrometry  proteomics  hybridization capture 
UnknownComparative Analysis of Species-Specific Hepatocyte Function and Drug Effects in a Liver Microphysiological System PhysioMimix LC12 and 96-Well Plates.
Not available
S-EPMC12624441 | biostudies-literature
ProteomicsStradard protein and yeast top-down data
We developed a novel dissociation strategy in the data acquisition process, the Mesh strategy to dissociate multiple charge states of one proteoform with stepped HCD (high collision energy dissociation). We proved that the ‘Mesh’ strategy could generate fragments with improved sequence coverage and...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2022-06-09 | PXD022941 | Pride
Stepped hcd Instrument control Real-time Mesh Top-down 
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