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TranscriptomicsApplication of a multi-layer systems toxicology framework for in vitro assessment of the biological effects of Classic Tobacco e-liquid and its corresponding aerosol using a novel e-cigarette device with MESH(TM) technology (microRNA data)
We previously put forward a multi-layer systems toxicology framework for in vitro assessment of e-liquids that is meant to complement the battery of classical assays for genotoxicity testing. The framework started with the first layer to screen e-liquids for their potential toxicity, followed by the...
ORGANISM(S): Homo sapiens 
2019-11-01 | E-MTAB-7912 | biostudies-arrayexpress
TranscriptomicsApplication of a multi-layer systems toxicology framework for in vitro assessment of the biological effects of Classic Tobacco e-liquid and its corresponding aerosol using a novel e-cigarette device with MESH(TM) technology (mRNA data)
We previously put forward a multi-layer systems toxicology framework for in vitro assessment of e-liquids that is meant to complement the battery of classical assays for genotoxicity testing. The framework started with the first layer to screen e-liquids for their potential toxicity, followed by the...
ORGANISM(S): Homo sapiens 
2019-11-01 | E-MTAB-7911 | biostudies-arrayexpress
ProteomicsPolypropylene mesh implantation for hernia repair triggers myeloid cell-dependent persistent inflammatory foreign body reaction
Polypropylene meshes that are commonly used for surgical groin hernia repair may trigger granulomatous foreign body reactions. Here, we show that asymptomatic patients display mesh-associated inflammatory granulomas long after surgery, which are dominated by monocyte-derived macrophages. In mice, su...
ORGANISM(S): Mus musculus (Mouse) 
2019-01-24 | PXD009944 | Pride
Mouse Inflammation Chemokine Granuloma Macrophages Monocytes Biomaterial 
ProteomicsStradard protein and yeast top-down data
We developed a novel dissociation strategy in the data acquisition process, the Mesh strategy to dissociate multiple charge states of one proteoform with stepped HCD (high collision energy dissociation). We proved that the ‘Mesh’ strategy could generate fragments with improved sequence coverage and...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2022-06-09 | PXD022941 | Pride
Stepped hcd Instrument control Real-time Mesh Top-down 
TranscriptomicsTranscription profiling of human fibroblasts grown on TCPS plates, Collagen-GAG 2 D plate and Collagen-GAG 3D mesh
All mRNA was isolated after 8 hours of culture time in each of three culture conditions. (1) TCPS Plate, (2) Collagen-GAG 2 dimensional coated plate and (3) collagen-GAG three dimensional mesh.
ORGANISM(S): Homo sapiens 
2008-06-11 | E-GEOD-1937 | biostudies-arrayexpress
TranscriptomicsIMR-90 cells: Collagen Mesh Time Course
A series of chips with some repeated measurments. Each chip represents a pool of 4 collagen/chondroitin sulfate tissue engineering scaffold meshes seeded with 1 x 10^6 IMR-90 Human Fibroblasts. mRNA was isolated at 30 minutes, 1, 2, 4, 8, 12, 24, 48, and 72 hours after seeding. Keywords = tissue eng...
ORGANISM(S): Homo sapiens 
2003-09-10 | GSE409 | GEO
TranscriptomicsExposure to aerosol of an e-vapor device with MESH™ technology had a lower biological impact than exposure to cigarette smoke on human bronchial and alveolar culture models: an in vitro systems toxicology assessment.
The harmful effects of cigarette smoke exposure on the respiratory tract are widely known. Exposure to aerosol from electronic vapor (e-vapor) products has been suggested to result in less risk of harm to smokers than CS exposure. Many studies have assessed the potential toxicity of the aerosol from...
ORGANISM(S): Homo sapiens 
2021-01-31 | E-MTAB-10071 | biostudies-arrayexpress
UnknownMeshable: searching PubMed abstracts by utilizing MeSH and MeSH-derived topical terms.
Not available
S-EPMC5039918 | biostudies-literature
UnknownMesh deformation: A mechanism underlying polypropylene prolapse mesh complications in vivo.
Not available
S-EPMC9453339 | biostudies-literature
Genomicsfungus metagenome
Fungal metagenome in mesh bags
PRJNA416438 | ENA
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