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ProteomicsProteomic analysis of centrosome-associated proteins between non-activated non-polarized and activated polarized murine B cells R#1 (R#2 doi: 10.1038/ncomms10969) & R#3
Using stable isotope labelling by amino acids in cell culture (SILAC)-based quantitative proteomics on purified centrosomes from resting, non-activated non-polarized, and activated polarized mouse B cells, we established a list of proteins differentially associated with the centrosome between restin...
ORGANISM(S): Mus musculus (Mouse) 
2022-12-12 | PXD038725 | Pride
Centrosome Polarity B cells Antigen stimulation 
ProteomicsExtracellular vesicles from fibroblasts stimulated by FGF2
We compared proteomic analysis of extracellular vesicles (EVs) secreted from human dermal fibroblasts, either control or stimulated by FGF2 and after immunoprecipitation with FGF2-coated beads to isolated FGF2-positive EVs.
ORGANISM(S): Homo sapiens (Human) 
2022-12-20 | PXD033141 | Pride
Extracelular vesicles Fibroblasts Fgf2 
ProteomicsThe oncogenic role of Streptococcus gallolyticus subsp. Gallolyticus - Proteome Part 2
Streptococcus gallolyticus subsp. gallolyticus (SGG), an opportunistic gram-positive pathogen responsible for septicemia and endocarditis in the elderly, is often associated with colon cancer (CRC). In this work, we investigated the oncogenic role of SGG strain UCN34 using the azoxymethane (AOM)-ind...
ORGANISM(S): Mus musculus (Mouse) 
2023-09-22 | PXD038268 | Pride
Phosphoproteome Streptococcus gallolyticus Proteome Colorectal cancer 
ProteomicsThe oncogenic role of Streptococcus gallolyticus subsp.- Proteome Part 1
Streptococcus gallolyticus subsp. gallolyticus (SGG), an opportunistic gram-positive pathogen responsible for septicemia and endocarditis in the elderly, is often associated with colon cancer (CRC). In this work, we investigated the oncogenic role of SGG strain UCN34 using the azoxymethane (AOM)-ind...
ORGANISM(S): Mus musculus (Mouse) 
2023-09-22 | PXD038267 | Pride
Phosphoproteome Streptococcus gallolyticus Proteome Colorectal cancer 
ProteomicsThe oncogenic role of Streptococcus gallolyticus subsp. Gallolyticus-Phosphoproteome-Part1
Streptococcus gallolyticus subsp. gallolyticus (SGG), an opportunistic gram-positive pathogen responsible for septicemia and endocarditis in the elderly, is often associated with colon cancer (CRC). In this work, we investigated the oncogenic role of SGG strain UCN34 using the azoxymethane (AOM)-ind...
ORGANISM(S): Mus musculus (Mouse) 
2023-09-22 | PXD038270 | Pride
Phosphoproteome Streptococcus gallolyticus Proteome Colorectal cancer 
ProteomicsThe oncogenic role of Streptococcus gallolyticus subsp. Gallolyticus - Phosphoprotéome Part2
Streptococcus gallolyticus subsp. gallolyticus (SGG), an opportunistic gram-positive pathogen responsible for septicemia and endocarditis in the elderly, is often associated with colon cancer (CRC). In this work, we investigated the oncogenic role of SGG strain UCN34 using the azoxymethane (AOM)-ind...
ORGANISM(S): Mus musculus (Mouse) 
2023-09-22 | PXD038272 | Pride
Phosphoproteome Streptococcus gallolyticus Proteome Colorectal cancer 
ProteomicsRelB function in lipid metabolism
Study of the role of the transcription factor RelB (alternative NF-kappaB subunit) in the control of lipid metabolism.
ORGANISM(S): Homo sapiens (Human) 
2026-09-28 | PXD074627 | Pride
Hcc derived cell lines 
ProteomicsNucleolin uses its RBD2 domain to recognize long-loop G-Quadruplexes from human minisatellite CEB25
We investigated herein the interaction between nucleolin (NCL) and a set of G4 sequences derived from the CEB25 human minisatellite which adopt a parallel topology while differing by the length of the central loop (from 9nt to1nt). It is revealed that NCL strongly binds to long-loop (9-5 nt) G4 whil...
ORGANISM(S): Homo sapiens (Human) 
2020-03-19 | PXD016529 | Pride
Rna binding domain G4-ligands Proteomics G-quadruplex Rgg domain Photo-crosslinking Nucleolin Long loop 
ProteomicsH3 N-terminal tail peptide interactome
The closely related replicative H3 and non-replicative H3.3 variants show specific requirement during development in vertebrates. Whether it involves distinct mode of deposition or unique roles once incorporated into chromatin remains unclear. To disentangle the two aspects, we took advantage of the...
ORGANISM(S): Xenopus laevis (African clawed frog) 
2020-03-13 | PXD016497 | Pride
Xenopus laevis Development Histone variant H3.3s31 
ProteomicsRagG interactome analysis in human breast MDA-MB-231 cells
RagC was immunoprecipitated from human breast cancer MDA-MB-231 cells treated or not with the Arp2/3 complex inhibitor, CK666, and the RagC interactome was analyzed by mass-spectrometry.
ORGANISM(S): Homo sapiens (Human) 
2023-09-04 | PXD027100 | Pride
Ragc Breast cancer cells Mtor Lysosomes 
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