Sort   by:  
 Page size 
This study highlights that organs can have variable sub-proteomes that do not necessarily correspond to anatomical features. The bovine heart as a model demonstrates at least 3-5 separate proteomes exist within a 2D plane of the heart. The main differences between these proteomes were the biochemica...
ORGANISM(S): Bos taurus (Bovine) 
2024-10-17 | PXD013375 | Pride
SH-Sy5y cells were exposed to glucosylsphingosine (GlcSph) at two concentrations observed in moderate (20 ng/mL) and severe (200 ng/mL) Gaucher disease phenotypes and subjected to label free proteomics to identify cellular pathways and molecules affected by GlcSph. Lyso-Gb3, a lipid accumulating in ...
ORGANISM(S): Homo sapiens (Human) 
2025-09-01 | PXD061666 | Pride
The templated misfolding of tau proteins accounts for tau pathology spread in Alzheimer’s disease (AD). Post-translational modifications, including phosphorylation at specific residues, are closely linked with tau seeding ability and clinical disease progression. This study investigates the role of ...
ORGANISM(S): Homo sapiens (Human) 
2025-05-07 | PXD056614 | Pride
Transcriptional profiling of HIV-1 infected and that of IFNbeta, IFNgamma or LPS stimulated human monocyte derived macrophages.
ORGANISM(S): Homo sapiens 

Neuroblastoma is a malignancy of the developing sympathetic nervous system that most commonly affects young children and is often lethal. The etiology of this embryonal cancer is not known.

We have performed a whole genome scan for association of neuroblastoma with SNP genotypes an...

As disease-modifying therapies are now available for Alzheimer’s disease (AD), accessible, accurate and affordable biomarkers to support diagnosis are urgently needed. We sought to develop a mass spectrometry-based urine test as a high-throughput screening tool for diagnosing AD. We collected urine...
ORGANISM(S): Homo Sapiens 
Sort   by:  
 Page size