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ProteomicsAbsence of MCJ/DnaJC15 promotes brown adipose tissue thermogenesis
Obesity poses a global health challenge, demanding a deeper understanding of adipose tissue (AT) and its mitochondria. This study describes the role of the mitochondrial protein Methylation-controlled J protein (MCJ/DnaJC15) in orchestrating brown adipose tissue (BAT) thermogenesis. Here we show how...
ORGANISM(S): Mus musculus (Mouse) 
2024-11-13 | PXD057026 | Pride
Proeomics Mouse Lipidomics Adipose tissue 
UnknownHeme Oxygenase 1 and 2 Common Genetic Variants and Risk for Essential Tremor.
Not available
S-EPMC4616553 | biostudies-literature
OtherAssessment of a method to characterize antibody selectivity and specificity for use in immunoprecipitation.
Data from ProteomeXchange, PXD ID: PXD002534. File: GR_130129_20_OT3_NT_L3MBTL2_FAB_31_G11_2_HEK293.mzXML. Published as part of Nat Methods. 2015 Jun 29 . From the Abstract: {{i}} ... We describe a mass spectrometry-based standard operating procedure for scoring immunoprecipitation antibody quality...
ORGANISM(S): Homo_sapiens_viruses, Human_female 
GPM32320016573 | GPMDB
Resource Reanalysis 
UnknownGenetic and physical interaction of the B-cell systemic lupus erythematosus-associated genes BANK1 and BLK.
Not available
S-EPMC3268679 | biostudies-literature
UnknownNatalizumab and fumarate treatment differentially modulate CD4+ T cell and B cell subtypes in multiple sclerosis patients without impacting durable COVID-19 vaccine responses.
Not available
S-EPMC12672258 | biostudies-literature
ProteomicsS6K1 Phosphoproteome in Tsc1-null mouse kidney iMCD3 cells
Loss of Tsc1 in the kidneys gives rise to rapid polycystogenesis and kidney failure due to the hyperactivation of mTOR complex I (mTORC1). One of the major downstream targets of mTORC1 is S6K1, which is responsible for driving many of the effector functions of mTOR. Strikingly, the loss of S6k1 in t...
ORGANISM(S): Mus musculus (Mouse) 
2020-08-11 | PXD014832 | Pride
S6k1 Tsc1 Kidney Phosphoproteome Mtor 
UnknownIntraoperative Oxidative Damage and Delirium after Cardiac Surgery.
Not available
S-EPMC7015795 | biostudies-literature
UnknownMechanisms of site-specific dephosphorylation and kinase opposition imposed by PP2A regulatory subunits.
Not available
S-EPMC7327492 | biostudies-literature
UnknownEffects of Evolocumab on the ApoA1 Remnant Ratio: A Pooled Analysis of Phase 3 Studies.
Not available
S-EPMC6525215 | biostudies-literature
UnknownRole of Increased n-acetylaspartate Levels in Cancer.
Not available
S-EPMC4849357 | biostudies-literature
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