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Lysergic acid diethylamide (LSD), considered the prototypical psychedelic molecule, has effects on consciousness and perception. However, the molecular mechanisms involved in LSD effects in human neural cells and how they may be translated into changes in physiology are still poorly understood. Here...
ORGANISM(S): Homo sapiens (Human) 
2024-10-17 | PXD027369 | Pride
Serotonin (5-hydroxytryptamine; 5-HT) 5-HT2-family receptors are the key targets of the prototypical psychedelic LSD. Although the canonical signaling pathway for 5-HT2 receptors is mediated by Gq protein, recent studies suggest that G-protein independent signaling, namely β-arrestin signaling pathw...
ORGANISM(S): Homo sapiens (Human) 
2023-10-24 | PXD030752 | Pride
This data set contains nano flow multi-omics single shot technology (nMOST) data collected from a collection of LSD mutant cell lines. Pilot data for nMOST method development is also included.
ORGANISM(S): Saccharomyces Cerevisiae (ncbitaxon:4932) Homo Sapiens (ncbitaxon:9606) Mus Musculus (ncbitaxon:10090) Caenorhabditis Elegans (ncbitaxon:6239) 
2024-02-28 | MSV000094201 | MassIVE
Lysergic acid diethylamide (LSD), considered the prototypical psychedelic molecule, has effects on consciousness and perception. However, the molecular mechanisms involved in LSD effects in human neural cells and how they may be translated into changes in physiology are still poorly understood. Here...
ORGANISM(S): Homo sapiens (Human) 
2024-10-17 | PXD037814 | Pride
Chronic LSD alters gene expression profiles in the mPFC relevant to schizophrenia [RNA-seq]
Chronic administration of lysergic acid diethylamide (LSD) every other day to rats results in a variety of abnormal behaviors. These build over the 90 day course of treatment and can persist at full strength for at least several months after cessation of treatment. The behaviors are consistent with ...
ORGANISM(S): Rattus norvegicus 
2021-11-11 | GSE179379 | GEO
Genomics
LSD related cancer
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