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In order to elucidate the molecular mechanism giving rise to the rare In(Lu) type of Lu(a-b-) blood group phenotype we compared the transcriptome of normal and In(Lu) erythroblasts at different stages of maturation. Many erythroid-specific genes had reduced transcript levels suggesting the phenotype...
ORGANISM(S): Homo sapiens 
Enrichment of metabolically labelled intact S-acylated peptides and subsequent analysis by LC-MS/MS
ORGANISM(S): Homo Sapiens 
2023-12-10 | PXD047685 |
We used iTRAQ technology to investigate the protein expression characteristics of S-RNases in S-gene homozygous germplasm. By using MaxQuant to search the raw mass spectrometry data files against the protein database, a total of 30,503 identified spectra, 13,568 peptides, and 4,472 proteins were ide...
ORGANISM(S): Pyrus pyrifolia 
2024-01-26 | PXD043543 | Pride
The synthesis of starch-like glucans can be reconstituted in S. cerevisiae using the genes from Arabidopsis thaliana: heterologous expression of SS1 to SS4, BE2, BE3, ISA1, and ISA2, together with a bacterial ADPglucose pyrophosphorylase gene for substrate provision in yeast strain 29, yielded insol...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2022-09-05 | PXD032241 | Pride
DNA methylation is a key epigenetic regulator of mammalian embryogenesis and somatic cell differentiation. Using high-resolution genome-scale maps of methylation patterns, we show that the formation of myelin in the peripheral nervous system, proceeds with progressive DNA demethylation, which coinci...
ORGANISM(S): Mus musculus 
S-nitrosylation is an important post-translational modification which occurs on cysteine in organisms. S-nitrosylation regu-lates signal transduction in many cell processes and aberrant S-nitrosylated (SNO-) proteins are closely related to cardiovas-cular and neurological diseases. However, quantita...
ORGANISM(S): Homo Sapiens 
2020-07-30 | PXD020657 |
S-acylation, dissolvable gel, sample treatment, proteomics
ORGANISM(S): Mus Musculus 
2024-06-04 | PXD052808 |
The transcriptome of the planarian Schmidtea mediterranea is not well characterized. We have used RNA-Seq to characterize the transcriptome in both sexual and asexual strains of S. mediterranea from both untreated and irradiated animals. Moreover, we have performed RNA-Seq on RNA purified from FAC...
ORGANISM(S): Schmidtea mediterranea 
Secreted extracellular vesicles play an important role in pathogen-host interactions. Increased knowledge of schistosome extracellular vesicles could provide insights into schistosome-host interactions and enable the development of novel intervention strategies to inhibit parasitic processes and les...
ORGANISM(S): Schistosoma japonicum (Blood fluke) 
2018-10-27 | PXD003364 | Pride
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