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TranscriptomicsBlood pooling experiments on ophthalmalogic phenotypes with Illumina arrays
In this study 3 pooling experiments were performed. In each of the 3 cohorts, a 'case' and a 'control' blood pool was compared - the goal being to identify single nucleotide polymorphisms with significantly different estimated pooling allele frequencies between cases and controls. For cohort 1, 100 ...
ORGANISM(S): Homo sapiens 
2009-08-08 | E-GEOD-17557 | biostudies-arrayexpress
ModelsMacGregor2005_HypothalamicSystems
This a model from the article: Modelling the hypothalamic control of growth hormone secretion. MacGregor DJ, Leng G. J Neuroendocrinol 2005;17(12):788-803 16280026 , Abstract: Here, we construct a mathema...
2005-01-01 | MODEL9811206584 | BioModels
TranscriptomicsHOS1 versus hos1 mRNA sequencing
Sequencing of mRNA extracted from 14 day old Columbia and hos1-3 seedlings grown at 22C 12:12 light dark Cold acclimation has been shown to be attenuated by the degradation of the INDUCER OF CBF EXPRESSION1 protein by the E3 ubiquitin ligase HIGH EXPRESSION OF OSMOTICALLY RESPONSIVE GENES1 (HOS1). H...
ORGANISM(S): Arabidopsis thaliana 
2016-07-21 | E-GEOD-84606 | biostudies-arrayexpress
TranscriptomicsHigh throughput screening for chemical inducers of stumpy formation in Trypanosoma brucei
During the bloodstream stage of the Trypanosoma brucei lifecycle, the parasite exists as the proliferative slender-form or the non-proliferative, transmissible, stumpy-form. The transition from the slender to stumpy-form is stimulated by a density-dependent mechanism and is important in infection dy...
ORGANISM(S): Trypanosoma brucei brucei 
2014-01-21 | E-GEOD-46483 | biostudies-arrayexpress
UnknownAdopting an American framework to optimize nursing admission documentation in an Australian health organization.
Not available
S-EPMC9272497 | biostudies-literature
TranscriptomicsDormancy of green-cotyledon Col seeds matured at 20°C vs 15°C
To determine genes involved in induction of dormancy in response to reduced maturation temperatures, RNA sequencing was performed on developing seeds matured at 20°C, where low dormancy is observed, and compared to seeds matured at 15°C where high dormancy is observed. Col green cotyledon seeds matu...
ORGANISM(S): Arabidopsis thaliana 
2014-09-04 | E-GEOD-61061 | biostudies-arrayexpress
GenomicsA novel recurrent mutation in MITF predisposes to familial and sporadic melanoma

We conducted whole-genome sequencing of probands from several melanoma families, identifying one individual carrying a novel germline variant (c.G1075A, NM_000248.3; p.E318K, NP_000239.1; rs149617956) in the melanoma lineage-specific oncogene MITF. While the variant cosegregated with melanoma in ...

phs000419.v1.p1 | EGA
ProteomicsMapping diversity in African trypanosomes using high resolution spatial proteomics
African trypanosomes are dixenous eukaryotic parasites that impose a significant human and veterinary disease burden on sub-Saharan Africa. Diversity between species and life-cycle stages is concomitant with distinct host and tissue tropisms within this group. Here, the spatial proteomes of two Afri...
ORGANISM(S): Trypanosoma brucei Trypanosoma congolense 
2023-10-22 | PXD035426 | Pride
Trypanosoma brucei Hyperlopit African trypanosomes Spatial proteome Parasite diversification Speciation Trypanosoma congolense Protein localisation 
UnknownBase-Promoted, Remote C-H Activation at a Cationic (η5-C5Me5)Ir(III) Center Involving Reversible C-C Bond Formation of Bound C5Me5.
Not available
S-EPMC6396953 | biostudies-literature
ProteomicsA VEL3 histone deacetylase complex establishes a maternal epigenetic state controlling progeny seed dormancy
Mother plants play an important role in the control of dormancy and dispersal characters of their progeny. In Arabidopsis seed dormancy is imposed by the embryo-surrounding tissues of the endosperm and seed coat. Here we show that VERNALIZATION5/VIN3-LIKE 3 (VEL3) maintains maternal control over pro...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2023-03-24 | PXD041094 | Pride
Maternal control Epigenetics Programmed cell death Endosperm Seed dormancy 
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