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Loss or damage to the mandible due to trauma, treatment of oral malignancies, and other diseases is currently treated using bone grafting techniques that suffer from numerous shortcomings and contraindications. Zebrafish naturally heal large injuries to their mandibular bone, and thus offer an oppor...
ORGANISM(S): Danio rerio (Zebrafish) (Brachydanio rerio) 
2022-03-07 | PXD027280 | Pride
Denisovans are an extinct hominin group defined by ancient genomes of Middle to Late Pleistocene fossils from southern Siberia. Although genomic evidence suggests their widespread distribution throughout eastern Asia and possibly Oceania, so far only a few fossils from the Altai and Tibet are confid...
ORGANISM(S): Homininae Palaeoloxodon sp. Suidae 
2025-04-09 | PXD054412 | Pride
Role of skeletal muscle in mandible development.
8-week-old mouse mandible scRNA-seq reveals bone marrow microenvironment
Genomics
single cell transcriptome of Mouse mandible
Previous analysis of Myf5-/-:MyoD-/- mouse fetuses lacking skeletal muscle demonstrated the importance of muscle contraction and static loading in mouse skeletogenesis. Previous analysis of Myf5-/-:MyoD-/- mouse fetuses lacking skeletal muscle demonstrated the importance of muscle contraction and st...
ORGANISM(S): Mus musculus 
2018-01-30 | GSE109779 | GEO
The mandible of the jawed vertebrate is derived from the mandibular process of the first pharyngeal arch of the early embryo. The first pharyngeal arch consists of cells from all three germ layers, with the neural crest giving rise to all the skeletal elements of the mandible. The correct patterning...
ORGANISM(S): Mus musculus 
2024-01-10 | GSE222566 | GEO
In this study, beta-TCP was implanted in dog mandibles, after which the gene expression profiles and signaling pathways were monitored using microarray and Ingenuity Pathways Analysis (IPA). Following the extraction of premolars and subsequent bone healing, beta‑TCP was implanted into the artifici...
ORGANISM(S): Canis lupus familiaris 
Axolotl mandible regeneration occurs through mechanical gap closure and a shared regenerative program with the limb
We explored the cellular composition of the bone marrow stroma by scRNA-seq profiling from mice mandible of 8-week-old. After viability assessment, 3,568 high-quality cells were captured using the 10x Genomics Chromium Single Cell platform, with rigorous quality control thresholds: >500 UMIs/cell, <...
ORGANISM(S): Mus musculus 
2026-04-01 | GSE316924 | GEO
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