Map7 - OmicsDI

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These mice have a relatively normal first wave of spermatogenesis but never become fertile. Older animals show increased apoptosis of germ cells, increasing in severity as germ cell stage advances. (1)
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Department of Biomedical Genetics, University of Rochester Medical Center, Rochester, NY 14642, USA Wilmot Cancer Institute, University of Rochester Medical Center, Rochester, NY 14642, USA (1)
Pedro R. Cutillas Professor of Cell Signalling & Proteomics Centre for Genomics and Computational Biology Barts Cancer Institute - a Cancer Research UK Centre of Excellence Queen Mary, University of London John Vane Science Centre, Charterhouse Square, London EC1M 6BQ (1)

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Microtubule associated proteins MAP7 and MAP7D1 promote 53BP1-mediated DNA double strand break repair in G1 cell cycle phase

In this project we have been looking for proteins binding to phosphorylated sites in DNA repair proteins. Previously, we and others have used peptide-pull down assays as a direct means of attributing specific binding functions to known sites phosphorylated by CK2 in DDR proteins. We have now applied...

ORGANISM(S): Homo sapiens (Human)

2023-03-01 | PXD033715 | Pride