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ProteomicsStrain- and cell type-specific influenza A virus (IAV)-host protein-protein interaction (PPI) network identified by affinity purification-mass spectrometry (AP-MS)
Influenza A Virus (IAV) is a recurring respiratory virus with antiviral therapies of limited use. Understanding host proteins essential for IAV infection can identify targets for alternative host-directed therapies (HDTs). Using affinity purification-mass spectrometry and global phosphoproteomic and...
ORGANISM(S): Homo sapiens (Human) 
2023-07-25 | PXD036077 | Pride
Virus-host H5n1 Human Ppi H1n1 A549 Nhbe H3n2 Thp-1 Ap-ms Influenza a virus 
ProteomicsGlobal Protein Abundance and Phosphorylation Analyses of Influenza A Virus (IAV)-Infected Human Cells
Influenza A Virus (IAV) is a recurring respiratory virus with antiviral therapies of limited use. Understanding host proteins essential for IAV infection can identify targets for alternative host-directed therapies (HDTs). Using affinity purification-mass spectrometry and global phosphoproteomic and...
ORGANISM(S): Homo sapiens (Human) 
2023-07-25 | PXD035900 | Pride
Human H5n1 H1n1 Protein abundance Phosphorylation Nhbe H3n2 Thp-1 Infection Influenza a virus 
ProteomicsEndogenous pull-downs of human proteins ATP6V1A and AHNAK to validate interactions with influenza A virus proteins M2 and NEP by targeted mass spectrometry in virus-infected cells
Influenza A Virus (IAV) is a recurring respiratory virus with antiviral therapies of limited use. Understanding host proteins essential for IAV infection can identify targets for alternative host-directed therapies (HDTs). Using affinity purification-mass spectrometry (AP-MS) and global phosphoprote...
ORGANISM(S): Homo sapiens (Human) 
2023-07-25 | PXD041663 | Pride
Virus-host Protein-protein interaction H5n1 Prm Human A549 Nhbe Influenza a virus 
UnknownPharmacogenetics for genes associated with age-related macular degeneration in the Comparison of AMD Treatments Trials (CATT).
Not available
S-EPMC3633658 | biostudies-literature
UnknownFluorescein angiography versus optical coherence tomography for diagnosis of uveitic macular edema.
Not available
S-EPMC3758459 | biostudies-literature
UnknownDiffusion Tensor Imaging Reveals Elevated Diffusivity of White Matter Microstructure that Is Independently Associated with Long-Term Outcome after Mild Traumatic Brain Injury: A TRACK-TBI Study.
Not available
S-EPMC9529303 | biostudies-literature
ProteomicsDeciphering the role of PGRMC2 in the human endometrium during the menstrual cycle and in vitro decidualization using an in vitro approach
Understanding how P4 signaling occurs in endometrial cells is important to guide the development of more effective therapeutic approaches to the numerous reproductive diseases caused by disrupted P4 signaling, resulting in subfertility or infertility (Bunch et al., 2013; Kim et al., 2013; Zhang and ...
ORGANISM(S): Homo sapiens (Human) 
2024-06-22 | PXD048494 | Pride
Proteomics Pgrmc2 Menstrual cycle Progesterone receptor Progesterone Decidualization Human endometrium Endometrial stromal cells Transcriptomics 
TranscriptomicsQuantitation of microRNAs in seminal fluid from men with and without prostate cancer
The objective of this study was to determine whether prostate cancer-associated miRNAs are present in seminal fluid and, if so, evaluate their diagnostic potential. Small RNA sequencing was used to profile and compare miRNAs in the non-sperm cellular fraction of seminal fluid from men with biopsy-pr...
ORGANISM(S): Homo sapiens 
2014-04-15 | E-GEOD-56686 | biostudies-arrayexpress
ProteomicsProteasome inhibitor-induced modulation reveals the spliceosome as a specific therapeutic vulnerability in multiple myeloma
Resistance to proteasome inhibitors (PIs) is a ubiquitous clinical concern in multiple myeloma. We proposed that signaling-level responses after PI would reveal new means to enhance efficacy. Unbiased phosphoproteomics after the PI carfilzomib surprisingly demonstrated the most prominent phosphory...
ORGANISM(S): Homo sapiens (Human) 
2020-02-21 | PXD012172 | Pride
Cancer Multiple myeloma Splice factor Spliceosome Lc-msms phosphoproteomics Proteasome inhibition Splicing Alternative splicing 
ProteomicsPROTEOMIC AND FUNCTIONAL ANALYSIS OF ALPACA (VICUGNA PACOS) SPERM QUALITY FOLLOWING IN VITROCAPACITATION WITH FOLLICULAR AND OVIDUCTAL FLUIDS
Assisted reproductive technologies, such as in vitro fertilization, remain inefficient in camelids, largely due to gaps in understanding the molecular interactions that regulate sperm capacitation. Fertilization requires not only viable spermatozoa but also precise modulation of capacitation by the ...
ORGANISM(S): Vicugna pacos 
2025-10-27 | PXD068210 | Pride
Oviductal fluid Follicular fluid Sperm quality South amercan camelids Spermatozoa 
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