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ProteomicsMitochondrial fatty acid synthesis coordinates oxidative metabolism in mammalian mitochondria
Cells harbor two systems for fatty acid synthesis, one in the cytoplasm (catalyzed by fatty acid synthase, FASN) and one in the mitochondria (mtFAS). In contrast to FASN, mtFAS is poorly characterized, especially in higher eukaryotes, with the major product(s), metabolic roles, and cellular function...
ORGANISM(S): Homo sapiens (Human) 
2020-09-02 | PXD021034 | Pride
Metabolism Mitochondria Electron transport chain Fatty acid synthesis Oxphos Respiration Reductive carboxylation Lipoylation tca cycle Muscle 
ProteomicsIdentifying Ceramide Protein Interactions using PISA
Ceramides are potent influencers of cell fate and function; however, their direct molecular target(s) and mechanism of action are poorly understood. In this study, we treated primary proximal tubule epithelial cells with C2-ceramide (50uM) or its precursor C2-dihydroceramide (50uM) and used proteome...
ORGANISM(S): Mus musculus (Mouse) 
2026-06-08 | PXD067617 | Pride
Ptec Mouse Pisa 
UnknownFurther pathogenicity testing of Verticillium nonalfalfae, a biocontrol agent against the invasive Tree of Heaven (Ailanthus altissima), on non-target tree species in Europe.
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S-EPMC9638367 | biostudies-literature
UnknownSchistosoma mansoni antigen induced innate immune memory features mitochondrial biogenesis and can be inhibited by ovarian produced hormones.
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S-EPMC11761400 | biostudies-literature
UnknownJMJD8 facilitates hepatic lipid deposition and metabolic dysfunction.
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S-EPMC12637200 | biostudies-literature
UnknownMitochondrial fatty acid synthesis coordinates oxidative metabolism in mammalian mitochondria.
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S-EPMC7470841 | biostudies-literature
UnknownSex- and age-dependence of region- and layer-specific knee cartilage composition (spin-spin-relaxation time) in healthy reference subjects.
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S-EPMC5318246 | biostudies-literature
UnknownAlternative splicing of UCP1 by non-cell-autonomous action of PEMT.
Not available
S-EPMC6889607 | biostudies-literature
UnknownNampt Potentiates Antioxidant Defense in Diabetic Cardiomyopathy.
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S-EPMC8513534 | biostudies-literature
UnknownSphingosine-1-phosphate controls endothelial sphingolipid homeostasis via ORMDL.
Not available
S-EPMC9827560 | biostudies-literature
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