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ProteomicsAn essential role for EROS in redox-dependent endothelial signal transduction
HUVEC cell were treated with siEROS and siRac1 to see the total proeome change in these primary cells
ORGANISM(S): Homo sapiens (Human) 
2024-05-20 | PXD052412 | Pride
Eros Redox Huvec 
ProteomicsDorsal root ganglia(DRG) proteomic analysis
Complete annotation mice dorsal root ganglia proteome
ORGANISM(S): Mus musculus (Mouse) 
2023-05-09 | PXD041382 | Pride
Dorsal root ganglia 
ProteomicsQuantitative proteomics of DAAO-TGTie2 aorta
We pursued a chemogenetic approach to create an animal model of aortic aneurysm formation using a transgenic mouse line DAAO-TGTie2 that expresses yeast D-amino acid oxidase (DAAO) under control of the endothelial Tie2 promoter. In DAAO-TGTie2 mice, DAAO generates the reactive oxygen species hydroge...
ORGANISM(S): Mus musculus (Mouse) 
2025-02-18 | PXD060737 | Pride
Daao-tgtie2 Aorta 
ProteomicsAorta proteomic analysis thoracic-abdominal
Aortic aneurysms is increasing as the human population ages. Pathological oxidative stress is implicated in development of aortic aneurysms. We pursued a chemogenetic approach to create an animal model of aortic aneurysm formation using a transgenic mouse line DAAO-TGTie2 that expresses yeast D-amin...
ORGANISM(S): Mus musculus (Mouse) 
2025-02-18 | PXD060700 | Pride
Oxidative stress Vascular biology Chemogenetics Aneurysm 
ProteomicsInternalization of therapeutic antibodies into Dendritic cells as a risk factor for immunogenicity
The appended raw files, csv files and other documents were deposited into the public domain in support for the publication "Internalization of therapeutic antibodies into Dendritic cells as a risk factor for immunogenicity" by Michel Siegel, Anna-Lena Bolender, Axel Ducret, Johannes Fraidling, Katha...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2024-08-26 | MSV000095695 | MassIVE
TranscriptomicsThe expanded regulatory T cell population in chronic filarial infection is highly heterogeneous, activated and suppresses dendritic cell function indirectly through effector T cells.
Natural regulatory T cells (nTregs) are known to increase during chronic infection or at the site tumor, though the exact mechanisms that contribute to their accumulation and mode of action remain unclear. We used flow cytometry and microarray analyses to delineate the phenotype of nTregs and their ...
ORGANISM(S): Homo sapiens 
2016-02-25 | E-GEOD-44767 | biostudies-arrayexpress
UnknownIdentification of shared tumor epitopes from endogenous retroviruses inducing high-avidity cytotoxic T cells for cancer immunotherapy.
Not available
S-EPMC8791462 | biostudies-literature
TranscriptomicsTranscription profiling by array of human dendritic cells after Poly(I:C)-based or PGE2-based maturation
Generation of human monocyte-derived DCs Peripheral blood mononuclear cells (PBMC) were isolated by Ficoll density centrifugation from buffy coats or whole blood of healthy donors and resuspended in serum-free medium (CellGro, CellGenix GmbH, Freiburg, Germany), supplemented with penicillin (50U/ml)...
ORGANISM(S): Homo sapiens 
2008-11-01 | E-MEXP-1230 | biostudies-arrayexpress
UnknownMast cells expedite control of pulmonary murine cytomegalovirus infection by enhancing the recruitment of protective CD8 T cells to the lungs.
Not available
S-EPMC3999167 | biostudies-literature
ProteomicsDevelopment and qualification of a dendritic cell internalization assay contributing to the immunogenicity risk evaluation of biotherapeutics
The appended raw files, csv files and other documents were deposited into the public domain in support for the publication "Development and characterization of a dendritic cell internalization assay contributing to the immunogenicity risk evaluation of biotherapeutics" by Michel Siegel, Aman Padamse...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2024-08-12 | MSV000095578 | MassIVE
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