Sort   by:  
 Page size 
ProteomicsComplexome profiling of MICOS complex, impact of subunits MIC26 and MIC27
Here we analysed the impact of two subunits (MIC26 and MIC27) on the assembly and stability of the mitochondrial contact site and cristae organizing system (MICOS) complex.
ORGANISM(S): Homo sapiens (Human) 
2020-07-28 | PXD016732 | Pride
Micos Oxidative phosphorylation system Lc-msms Complexome profiling 
ProteomicsThe interactome of human MIC13, a subunit of MICOS complex
Description: MIC13 is a subunit of the mitochondrial contact site and cristae organizing system (MICOS) and essential for mitochondrial cristae structure. Here we enriched Mic13 by co-Immunoprecipitation and identified interacting proteins.
ORGANISM(S): Homo sapiens (Human) 
2025-01-02 | PXD044968 | Pride
Micos Mib Mitochondria Lc-msms 
ProteomicsDiverged Trypanosome MICOS as a Hub for Mitochondrial Cristae Shaping and Protein Import
The mitochondrial contact site and cristae organization system (MICOS) is a complex responsible for proper cristae formation. Empirical data about this ubiquitous complex is limited to opisthokont models (e.g. yeast), impeding understanding of its core properties and adaptation potential to diverse ...
ORGANISM(S): Trypanosoma brucei 
2018-09-13 | PXD009601 | Pride
Mitochondria  cristae  intermembrane space  micos  protein import  trypanosoma brucei  lc-ms/ms  label-free  tmt 
ProteomicsListeria monocytogenes exploits the MICOS complex subunit Mic10 to promote mitochondrial fragmentation and cellular infection
Mitochondrial function adapts to cellular demands and is affected by the ability of the organelle to undergo fusion and fission in response to physiological and non-physiological cues. We previously showed that infection with the human bacterial pathogen Listeria monocytogenes elicits transient mito...
ORGANISM(S): Homo sapiens (Human) 
2020-02-17 | PXD014667 | Pride
Micos complex Human Listeria monocytogenes Mitochondria Mic10 
ProteomicsThe MICOS-MIB complex member PERM1 connects mitochondria with the sarcolemma via ankyrin B
Skeletal muscle subsarcolemmal mitochondria (SSM) and intermyofibrillar mitochondria subpopulations have distinct metabolic activity and sensitivity, though the mechanisms that localize SSM to peripheral areas of muscle fibers are poorly understood. A protein interaction study and complexome profili...
ORGANISM(S): Homo sapiens (Human) Mus musculus (Mouse) 
2021-11-16 | PXD025745 | Pride
Mitochondria  skeletal muscle  perm1  proteomics 
UnknownGenetic ablation of Immt induces a lethal disruption of the MICOS complex.
Not available
S-EPMC10927357 | biostudies-literature
UnknownCoordination of cytochrome bc<sub>1</sub> complex assembly at MICOS.
Not available
S-EPMC11772845 | biostudies-literature
UnknownMitochondrial hepato-encephalopathy due to deficiency of QIL1/MIC13 (C19orf70), a MICOS complex subunit.
Not available
S-EPMC5117932 | biostudies-literature
UnknownPD-linked CHCHD2 mutations impair CHCHD10 and MICOS complex leading to mitochondria dysfunction.
Not available
S-EPMC6423417 | biostudies-literature
UnknownProtease OMA1 modulates mitochondrial bioenergetics and ultrastructure through dynamic association with MICOS complex.
Not available
S-EPMC7892988 | biostudies-literature
Sort   by:  
 Page size