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MetabolomicsComparison of Full-Scan, Data-Dependent, and Data-Independent Acquisition Modes in Liquid Chromatography-Mass Spectrometry Based Untargeted Metabolomics
Full-scan, data-dependent acquisition (DDA), and data-independent acquisition (DIA) are the three common data acquisition modes in high resolution mass spectrometry-based untargeted metabolomics. It is an important yet underrated research topic on which acquisition mode is more suitable for a given ...
2020-05-21 | MTBLS1572 | MetaboLights
MetabolomicsEvaluation of significant features discovered from different data acquisition modes in mass spectrometry-based untargeted metabolomics

Despite the growing popularity of liquid chromatography-mass spectrometry (LC-MS)-based metabolomics, no study has yet to systematically compare the performance of different data acquisition modes in the discovery of significantly altered metabolic features, which is an important task of untarget...

2020-10-02 | MTBLS1842 | MetaboLights
MetabolomicsTranscriptomic and metabolomic comparison of two Kandelia obovata cultivas in response to cold wave
Temperature is the primary environmental factor that restricts the growth and distribution of mangrove plants. With the escalating severity of global climate change, Kandelia obovata has gained widespread recognition as an ideal species for investigating the response mechanisms of mangroves to cold ...
2024-09-27 | MTBLS9845 | MetaboLights
UnknownThe WRKY Transcription Factor GmWRKY12 Confers Drought and Salt Tolerance in Soybean.
Not available
S-EPMC6320995 | biostudies-literature
MetabolomicsExplaining combinatorial effects of mycotoxins Deoxynivalenol and Zearalenone in mice with urinary metabolomic profiling
Urine metabolic profiling of mice was conducted utilizing gas chromatography-mass spectrometry (GC-MS) to investigate the combinatory effect of mycotoxins deoxynivalenol (DON) and zearalenone (ZEN) on the metabolism of the mice. Experiments were conducted by means of five-week-old mice which were in...
2021-02-11 | MTBLS580 | MetaboLights
MetabolomicsUPLC-QTOF-MS-Based Plasma Lipidomic Profiling Reveals Biomarkers for Inflammatory Bowel Disease Diagnosis
Identification of new biomarkers may help in the early diagnosis of inflammatory bowel disease (IBD). In this study, ultrahigh-performance liquid chromatography equipped with quadrupole time-of-flight mass spectrometry (UPLC-QTOF-MS) was used to analyze the untargeted lipidomics and compare plasma l...
2021-10-18 | MTBLS1183 | MetaboLights
ProteomicsArabidopsis Hrd1 complex - PAWH1 and PAWH2 are plant-specific components of an Arabidopsis endoplasmic reticulum-associated degradation complex
We are using the immunoprecipitation coupled with mass spectrometry to identify additional components of the Arabidopsis Hrd1-containing ERAD complex
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2019-08-15 | PXD013400 | Pride
Erad Pawh2 Hrd1 Ebs7 Upr Er stress Pawh1 
MetabolomicsCharacterization of Constituents with Potential Anti-Inflammatory Activity in Chinese Lonicera Species by UHPLC-HRMS Based Metabolite Profiling
This study centered on detecting potentially anti-inflammatory active constituents in ethanolic extracts of Chinese Lonicera species by taking an UHPLC-HRMS-based metabolite profiling approach. Extracts from eight different Lonicera species were subjected to both UHPLC-HRMS analysis and to pharmacol...
2022-11-17 | MTBLS3112 | MetaboLights
UnknownDown-regulated γ-catenin expression is associated with tumor aggressiveness in esophageal cancer.
Not available
S-EPMC4024793 | biostudies-literature
MetabolomicsLow chorionic villous succinate accumulation associates with recurrent spontaneous abortion risk
Dysregulated extravillous trophoblast invasion and proliferation are known to increase the risk of recurrent spontaneous abortion (RSA); however, the underlying mechanism remains unclear. Herein, in our retrospective observational case-control study we show that villous samples from RSA patients, co...
2021-10-06 | MTBLS2148 | MetaboLights
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