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ProteomicsYBEY is an essential biogenesis factor for mitochondrial ribosomes
The aim was to evaluate the protein composition of human mitoribosomes in YBEY knockout cells. We compared the parental cell line HEK293T-REx with the YBEY knockout cells HEK293T-RExΔYBEY.
ORGANISM(S): Homo sapiens (Human) 
2020-03-02 | PXD015310 | Pride
Ribosomes Mitochondira 
ProteomicsProteome analysis of testis from infertile protein C inhibitor deficient mice reveals predominant changes in serpin processing and prostaglandin metabolism
Serine protease inhibitors have therapeutic potential in a variety of pathogenic processes, ranging from thrombosis, altered immune response to liver cirrhosis. To investigate the physiological effects of protein C inhibitor (PCI, serpinA5) this gene was inactivated in a mouse model with the resulti...
ORGANISM(S): Mus musculus (Mouse) 
2015-12-07 | PXD002944 | Pride
Mouse Proteomics Serpin 
ProteomicsCD147 mutants affinity purification mass spectrometry from human T cells
CD147 is known as tumor and regulatory T cell marker and as regulator of chemotaxis, stress response or immune cell function; however, the mode of action of CD147 remains incompletely understood. Using affinity purification mass spectrometry (AP-MS) of HA-tagged CD147 swap and deletion mutants, we e...
ORGANISM(S): Homo sapiens (Human) 
2016-01-28 | PXD003029 | Pride
Human Jurkat Affinity purification Primary t cells Cd147 Lc-ms/ms 
ProteomicsConditioned medium from human iPSC-derived mesenchymal progenitors: Effect of extended progenitor cultivation vs. osteogenic pre-differentiation on the medium stimulatory activity
Human induced pluripotent stem cells provide an unlimited, scalable source of youthful tissue progenitors and secretome for regenerative therapies. The aim of our study was to assess the potential of conditioned medium (CM) derived from hiPSC-mesenchymal progenitors (hiPSC-MPs) to stimulate osteogen...
ORGANISM(S): Homo sapiens (Human) 
2025-05-07 | PXD052766 | Pride
Human ipscs Osteogenic differentiation Mesenchymal progenitors Proteomic analysis Conditioned medium Human bone marrow mesenchymal stromal cells Secretome Aging 
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