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UnknownMaturation stage-specific V-ATPase disassembly explains the neutral pH of mature mucocyst lysosome-related organelles in Tetrahymena thermophila.
Not available
S-EPMC12752500 | biostudies-literature
UnknownAn aspartyl cathepsin, CTH3, is essential for proprotein processing during secretory granule maturation in Tetrahymena thermophila.
Not available
S-EPMC4142616 | biostudies-literature
UnknownAn endosomal syntaxin and the AP-3 complex are required for formation and maturation of candidate lysosome-related secretory organelles (mucocysts) in Tetrahymena thermophila.
Not available
S-EPMC5449153 | biostudies-literature
ProteomicsProbing the genomic and proteomic basis of encystment in Oxytricha granulifera
Protozoan encystment is a crucial survival strategy for resisting environmental stresses, yet its molecular mechanisms remain poorly understood due to limited genomic resources and lack of integrated multi-omics analyses in model ciliates. In this study, we aimed to elucidate the molecular mechanism...
ORGANISM(S): Oxytricha granulifera 
2026-04-14 | PXD068223 | Pride
6ma Spliceosome Transcriptomic Cyst Mucocyst 
UnknownSecretion of Polypeptide Crystals from Tetrahymena thermophila Secretory Organelles (Mucocysts) Depends on Processing by a Cysteine Cathepsin, Cth4p.
Not available
S-EPMC4519746 | biostudies-literature
UnknownInferring gene-pathway associations from consolidated transcriptome datasets: an interactive gene network explorer for <i>Tetrahymena thermophila</i>.
Not available
S-EPMC11661410 | biostudies-literature
UnknownInferring gene-pathway associations from consolidated transcriptome datasets: an interactive gene network explorer for <i>Tetrahymena thermophila</i>.
Not available
S-EPMC12107436 | biostudies-literature
ProteomicsCharacterization of a novel membrane complex required for docking and regulated exocytosis of lysosome-related organelles in Tetrahymena thermophila
In the ciliate Tetrahymena thermophila, lysosome-related organelles called mucocysts accumulate at the cell periphery where they secrete their contents in response to extracellular events, a phenomenon termed regulated exocytosis. A forward genetic approach uncovered MDL1 (Mucocyst Discharge with a ...
ORGANISM(S): Tetrahymena thermophila CU428 
2022-04-06 | PXD028372 | Pride
Exocytosis Mucocysts Ciliate Tetrahymena Lysosome Mdl1 
UnknownA novel membrane complex is required for docking and regulated exocytosis of lysosome-related organelles in Tetrahymena thermophila.
Not available
S-EPMC9159632 | biostudies-literature
UnknownWhole Genome Sequencing Identifies a Novel Factor Required for Secretory Granule Maturation in Tetrahymena thermophila.
Not available
S-EPMC4978903 | biostudies-literature
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