Mycobacterium bovis

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Unknown (1290)
Genomics (369)
Transcriptomics (188)
Proteomics (44)
Metabolomics (8)
Methylation profiling (4)
Models (2)
Other (2)

Organisms

Homo sapiens (58)
Bos taurus (43)
Mycobacterium tuberculosis (32)
Mus musculus (31)
Mycobacterium tuberculosis variant bovis BCG (24)
Mycobacterium tuberculosis variant bovis (20)
Mycobacterium tuberculosis variant bovis BCG str. Pasteur 1173P2 (11)
Mycobacterium avium subsp. paratuberculosis (8)
Mycobacterium avium (7)
Mycobacterium tuberculosis H37Rv (6)
Staphylococcus aureus (6)
Yersinia enterocolitica (5)
Macaca mulatta (4)
Mycobacterium avium subsp. paratuberculosis K-10 (4)
Coxsackievirus B4 (strain E2) (3)
Human herpesvirus 4 type 1 (3)
Human herpesvirus 4 strain B95-8 (3)
Staphylococcus aureus A9635 (3)
Paraburkholderia fungorum (3)
Human rotavirus MP409 (3)
Prochlorococcus marinus str. MIT 9202 (3)
Torque teno virus (3)
Human Endogenous Retrovirus IDDMK1,2-22 (3)
Human endogenous retrovirus K (3)
Cervus elaphus hispanicus (2)
Cervus elaphus (2)
Bubalus bubalis (2)
Macaca fascicularis (1)
Xylella fastidiosa (1)
Drosophila melanogaster (1)

Organisms

Mycobacterium tuberculosis variant bovis (66)
Mycobacterium tuberculosis variant bovis BCG (36)
Bos taurus (24)
Homo sapiens (18)
Mus musculus (16)
Mycobacterium tuberculosis (9)
Mycobacterium tuberculosis variant bovis BCG str. Pasteur 1173P2 (8)
Mycobacterium tuberculosis variant bovis BCG str. Tokyo 172 (5)
Mycobacterium tuberculosis variant bovis BCG str. Moreau RDJ (2)
Mycobacterium (2)
Mycobacterium tuberculosis variant bovis BCG str. ATCC 35743 (1)
Mycobacterium tuberculosis variant bovis BCG str. ATCC 35740 (1)
Mycobacterium tuberculosis variant bovis BCG str. ATCC 35733 (1)
Mycobacterium tuberculosis variant bovis BCG str. China (1)
Mycobacterium tuberculosis variant bovis AF2122/97 (1)
Mycobacterium tuberculosis variant bovis BCG str. Phipps (1)
Mycobacterium tuberculosis variant bovis BCG str. Moreau (1)
Mycobacterium tuberculosis variant bovis BCG str. Sweden (1)
Mycobacterium tuberculosis variant bovis BCG str. Frappier (1)
Mycobacterium tuberculosis variant bovis BCG str. Prague (1)
Enterobacter sp. I4 (1)
Cervus elaphus hispanicus (1)
Pseudomonas sp. I3-I5 (1)
Mycobacterium tuberculosis variant bovis MAL010093 (1)
Mycobacterium tuberculosis variant bovis BCG str. Mexico (1)
Mycobacterium tuberculosis variant bovis B2 7505 (1)
Mycobacterium tuberculosis variant bovis Bz 31150 (1)
Mycobacterium tuberculosis variant bovis BCG str. Korea 1168P (1)
Mycobacterium tuberculosis variant bovis BCG str. Glaxo (1)
Cervus elaphus (1)

Repository

ENA (349)
geo (108)
biostudies-arrayexpress (99)
pride (29)
EGA (11)
iProX (7)
MetaboLights (6)
BioModels (2)
GNPS (2)
jPOST (2)
MassIVE (1)
PeptideAtlas (1)

Tissue

Cell culture (5)
Macrophage (5)
Prokaryotic cell (2)
Blood serum (1)
Lymph node (1)
Monocyte (1)
Thallus (1)

Disease

Tuberculosis (5)
Pulmonary tuberculosis (2)
Urinary bladder cancer (1)
Bovine tuberculosis (1)
Disease free (1)

Technology Type

Mass Spectrometry (29)
Shotgun proteomics (19)
Mass spectrometry (5)
Affinity purification coupled with mass spectrometry proteomics (4)
Bottom-up proteomics (3)
Gel-based experiment (2)
Mass spectrometry assay (1)
Data-dependent acquisition (1)
SWATH MS (1)

Instrument Platform

Illumina NovaSeq 6000 (4)
NanoDrop (2)
Illumina HiSeq 2500 (2)
NextSeq 500 (2)
TripleTOF 6600 (2)
Affymetrix 428 (1)
Agilent 2100 Bioanalyzer (1)
Chemostat (1)
Bellco roll-in incubator (1)
R (1)
TruSeq (Illumina, Novogene, Genomic Centre Cambridge, CB4 0FW, UK.) (1)
NanoDrop spectrophotometer and the Agilent 2100 Bioanalyzer (1)
Histopaque-1077,FACSAria Fusion Sorter,Flow Cytometer (1)
Ion Torrent Proton (1)
TripleTOF 5600 (1)
Flow injection analysis MS - negative (1)
Flow injection analysis MS - positive (1)
Liquid Chromatography Tandem MS (LC-MS/MS) (1)
Direct infusion MS - negative (1)
Liquid Chromatography MS - alternating - reverse phase (1)
Liquid Chromatography MS - positive - reverse-phase (1)
Liquid Chromatography MS - negative - reverse-phase (1)
Liquid Chromatography MS - negative - reverse phase (1)
Liquid Chromatography MS - negative - hilic (1)
Liquid Chromatography MS - positive - hilic (1)
LTQ Orbitrap XL (1)

Publication Date

2010 (30)
2025 (22)
2021 (20)
2014 (20)
2012 (15)
2024 (14)
2015 (14)
2022 (13)
2016 (13)
2023 (12)
2013 (11)
2009 (10)
2026 (9)
2020 (9)
2008 (9)
2007 (9)
2018 (8)
2011 (7)
2019 (7)
2017 (5)

CHEBI ID

CHEBI:16768 (2)
CHEBI:15781 (2)
CHEBI: 26707 (1)
CHEBI:16086 (1)
CHEBI:134344 (1)
CHEBI:15493 (1)
CHEBI:17769 (1)
CHEBI:15343 (1)
CHEBI:15412 (1)
CHEBI:80612 (1)
CHEBI:47878 (1)
CHEBI:17535 (1)
CHEBI:17279 (1)
CHEBI:16327 (1)
CHEBI:23673 (1)
CHEBI:51309 (1)
CHEBI:28895 (1)
CHEBI:16891 (1)
CHEBI:17256 (1)
CHEBI:30907 (1)
CHEBI:15531 (1)
CHEBI:17822 (1)
CHEBI:26271 (1)
CHEBI:17202 (1)
CHEBI:22660 (1)
CHEBI:27570 (1)
CHEBI:18186 (1)
CHEBI:26986 (1)
CHEBI:16811 (1)
CHEBI:17234 (1)

Metabolite Name

Glucose (2)
Methylcitrate (1)
Mycothiol (1)
Ergothioneine(1+) (1)
Maleylacetoacetic acid (1)
None (1)
Glycerol-phosphate (1)
6-Thioxanthine 5'-monophosphate (1)
L-gamma-glutamyl-L-cysteine (1)
N-Acetylneuraminate (1)
4-Aminobutyraldehyde (1)
Acetaldehyde (1)
2-Oxosuccinamate (1)
3-Hydroxybutyrate (1)
Acetate (1)
N(alpha),N(alpha),N(alpha)-trimethyl-L-histidine (1)
Leucine (1)
Glyoxylic acid (1)
Acetoacetate (1)
Valine (1)
O-Phosphoethanolamine (1)
Acetone (1)
Aconitic acid (1)
Allantoin (1)
Deoxyadenosine (1)
Phenylacetylglycine (1)
Citric acid (1)
Succinic acid (1)
Lysine (1)
Lactate (1)

First Public Date

2014 (43)
2025 (35)
2024 (34)
2021 (32)
2023 (25)
2022 (25)
2019 (25)
2026 (24)
2013 (24)
2015 (23)
2020 (21)
2017 (17)
2018 (12)
2016 (7)
2012 (2)

Modelling Approach

Constraint-based model (1)
Ordinary differential equation model (1)

Lab affiliation

Aix-Marseille Univ, Inserm, CNRS, Institut Paoli-Calmettes, CRCM, Marseille Protéomique (1)
Associate Professor Translational Health Science and Technology Institute NCR Biotech Science Cluster 3rd Milestone,Gurugram-Faridabad Expressway Faridabad-121001 (1)
Biosciences Institute, Newcastle University, Newcastle upon Tyne, United Kingdom (1)
Canadian Food Inspection Agency, Ottawa laboratory Fallowfield, Canada University of Ottawa, Canada (1)
Computational Biology Division, Department of Integrative Biomedical Sciences, IDM, University of Cape Town, South Africa (1)
DST/NRF Centre of Excellence for Biomedical Tuberculosis Research/South African Medical Research Council Centre for Tuberculosis Research, Division of Molecular Biology and Human Genetics, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa (1)
Department of Biology, Maynooth University, Co. Kildare, Ireland. Phone: + 353 - 1- 708 3859. Fax: + 353 - 1- 708 3845 (1)
Department of Biomedical Engineering, University of Florida, Gainesville FL (1)
Department of Integrative Biomedical Sciences & Institute of Infectious Disease and Molecular Medicine Faculty of Health Sciences, University of Cape Town Anzio, Observatory Cape Town 7925 South Africa (1)
Department of Intergrated Biomedical Sciences Institute of Infectious Disease and molecular medicine (1)
Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN 55905 (1)
Dipartimento di Biologia, Università di Napoli Federico II, Napoli, Italia (1)
Head of division: Integrative Biomedical Sciences (1)
Institut Pasteur, Paris, France (1)
Institut de Pharmacologie et de Biologie Structurale (IPBS), Université de Toulouse, CNRS, UPS, Toulouse, France (1)
Institut de Pharmacologie et de Biologie Structurale (IPBS), Université de Toulouse, CNRS, Université Toulouse III - Paul Sabatier (UT3), Toulouse, 31077, France (1)
Institute of Biochemistry and Biophysics, Polish Academy of Sciences (1)
Institute of Microbiology and Infection, School of Biosciences, University of Birmingham, Birmingham, B15 2TT UK (1)
Instituto de Salud Carlos III- Departamento de Inmunología Microbiana e Inmunogenética (1)
Laboratorio Interdisciplinar de Pesquisas Medicas, LIPMED,Instituto Oswaldo Cruz,IOC,Fundacao Oswaldo Cruz, FIOCRUZ,Rio de Janeiro,Brazil (1)
Laboratório de Genômica Funcional e Bioinformática- IOC/FIOCRUZ - RJ/Brasil (1)
Microbiology, Immunology and Pathology, Lab C210, Colorado State University, United States of America (1)
Proteomics Lab. SaBio research group. Instituto de Investigación en Recursos Cinegéticos, IREC (CSIC-UCLM.JCCM) (1)
SaBio. Instituto de Investigación en Recursos Cinegéticos IREC-CSIC-UCLM-JCCM, Ronda de Toledo s/n, 13005 Ciudad Real, Spain. (1)
Singapore Professor of Biological Engineering Professor of Biological Engineering Massachusetts Institute of Technology Department of Biological Engineering, 56-731 77 Massachusetts Ave. Cambridge, MA 02139 (1)
State Key Laboratory for Conservation and Utilization of Subtropical Agro-bioresources, College of Life Science and Technology, Guangxi University (1)
State Key Laboratory for Conservation and Utilization of Subtropical Agro-bioresources, College of Life Science and Technology, Guangxi University, Nanning, 530004, China (1)
University Center for Bioscience and Biotechnology, National Cheng Kung University (1)
University of Oxford (1)

IsPrivate

False (2)

Model Flag

Non Kinetic (1)

Submitter Keywords

Immuno-oncology (1)

Classification

bacteria (147)

Modification

6x(2)H labeled dimethylated L-arginine (1)
N6-dimethyl-L-lysine (1)

Study type

Transcription profiling by array (75)
RNA-seq of coding RNA (11)
Unknown experiment type (3)
Comparative genomic hybridization by array (2)
One-color microarray (1)
High-throughput sequencing (1)
Animal - High-throughput sequencing (1)
Bisulfite-seq (1)
MicroRNA profiling by array (1)
Proteomic profiling by array (1)
RNA-seq of total RNA (1)
RNA-seq of non coding RNA (1)

Release Date

2021 (116)
2022 (108)
2023 (102)
2020 (94)
2018 (93)
2019 (92)
2024 (89)
2025 (78)
2016 (67)
2017 (64)
2014 (63)
2015 (61)
2010 (53)
2013 (50)
2012 (48)
2011 (37)
2008 (31)
2009 (20)
2007 (19)
2006 (17)
2001 (16)
2002 (13)
2004 (10)
2026 (9)
2005 (8)
2000 (8)
1998 (8)
1999 (7)
2003 (6)
1997 (1)

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Integrated Transcriptomic and Metabolomic Analyses Reveal the Antibacterial Mechanism of Isocorydine against Mycobacterium bovis

Mycobacterium bovis, the causative agent of bovine tuberculosis, poses a significant zoonotic threat. This study defines the antibacterial activity and mechanism of the natural alkaloid isocorydine (ICD) against M. bovis using an integrated multi-omics approach. Phenotypic analyses demonstrated t...

2025-12-03 | MTBLS13441 | MetaboLights

Generation and characterization of thiol-deficient Mycobacterium tuberculosis mutants

Mycothiol (MSH) and ergothioneine (ERG) are thiols able to compensate for each other to protect mycobacteria such as Mycobacterium smegmatis against oxidative stress. Gamma-glutamylcysteine (GGC), another thiol and an intermediate in ERG biosynthesis has detoxification abilities. Five enzymes are in...

2018-07-05 | MTBLS661 | MetaboLights

Dissecting the Mycobacterium bovis BCG response to macrophage infection to identify targets for anti-tuberculosis drug and vaccine discovery

New strategies are required to reduce the worldwide burden of tuberculosis. Intracellular survival and replication of Mycobacterium tuberculosis after macrophage phagocytosis is a fundamental step in the complex host-pathogen interactions that lead to granuloma formation and disease. Greater underst...

ORGANISM(S): Mycobacterium tuberculosis variant bovis BCG str. Pasteur 1173P2

2022-01-14 | E-MTAB-11107 | biostudies-arrayexpress

Aspartate aminotransferase Rv3722c governs aspartate-dependent nitrogen metabolism in Mycobacterium tuberculosis

Gene rv3722c of Mycobacterium tuberculosis is essential for in vitro growth, and encodes a putative pyridoxal phosphate-binding protein of unknown function. Here we use metabolomic, genetic and structural approaches to show that Rv3722c is the primary aspartate aminotransferase of M. tuberculosis...

2020-05-01 | MTBLS1559 | MetaboLights

Comparative transcriptomics of Mycobacterium bovis and Mycobacterium marinum

Related surrogate species are often used to study the molecular basis of pathogenicity of a pathogen on the basis of a shared set of biological features generally attributable to a shared core genome consisting of orthologous genes. An important and understudied aspect, however, is the extent to whi...

ORGANISM(S): Mycobacterium bovis

2014-09-08 | E-GEOD-51881 | biostudies-arrayexpress

Inflammatory and immune responses in lymph nodes of Iberian red deer infected with Mycobacterium bovis.

Bovine tuberculosis (bTB), caused by Mycobacterium bovis (Mycobacterium tuberculosis complex), is a zoonotic disease that affects cattle and wildlife worldwide. In some regions of Spain, Iberian red deer (Cervus elaphus hispanicus) can serve as reservoir of infection, thus increasing the risk of hum...

ORGANISM(S): Cervus elaphus hispanicus

2007-10-17 | E-GEOD-6083 | biostudies-arrayexpress

Mycobacterium bovis-BCG vaccination induces a specific pulmonary transcriptome biosignature in mice

In the present study, we applied microarray technology to define a biosignature from the whole genome expression in lung and spleen samples after BCG vaccination and M. bovis infection of BALB/c mice. The aims were two-fold, namely to define biosignatures that could predict vaccine success before ch...

ORGANISM(S): Mus musculus

2010-07-29 | E-GEOD-21149 | biostudies-arrayexpress

DosR-regulon genes induction in Mycobacterium bovis BCG under aerobic conditions

In this report we demonstrated that under aerobic conditions, Mycobacterium bovis BCG expressing an hsp60-driven second copy of the hypoxia-related transcriptional regulator DosR increased 2-fold or greater the expression of 38 out of the 48 genes belonging to the DosR regulon, including the latency...

ORGANISM(S): Mycobacterium tuberculosis

2010-05-20 | E-GEOD-21932 | biostudies-arrayexpress

Transcription profiling of Mycobacterium bovis to determine genetic requirements for fast and slow growth in Mycobacteria

Mycobacterium tuberculosis infects a third of the world's population. Primary tuberculosis involving active fast bacterial replication is often followed by asymptomatic latent tuberculosis, which is characterised by slow or non-replicating bacteria. Reactivation of the latent infection involving a s...

ORGANISM(S): Mycobacterium bovis

2009-04-28 | E-BUGS-83 | biostudies-arrayexpress

Proteomic characterization of the culture supernatant of Mycobacterium bovis in different growth stages

The goal of this study is to identify the different proteins secreted by Mycobacterium bovis in the culture media at different stages of bacterial growth. A field strain of M. bovis was allowed to grow in a culture media and culture supernatant was collected at three-time points representing approxi...

ORGANISM(S): Bacteria Mycobacterium bovis

2021-12-30 | PXD017817 | Pride

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