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GenomicsPlasmodium histone H3 clipping
Cathepsin C-like protease regulates DNA replication by histone H3 N-terminal clipping in malaria parasites
PRJEB18114 | ENA
GenomicsHDAC1 has intrinsic protease activity and regulates transcription through clipping histone H3 N-terminal tail
HDAC1 has intrinsic protease activity and regulates transcription through clipping histone H3 N-terminal tail
PRJNA1137831 | ENA
UnknownCharacterization of N-Terminal Asparagine Deamidation and Clipping of a Monoclonal Antibody.
Not available
S-EPMC10525203 | biostudies-literature
TranscriptomicsHDAC1 has intrinsic protease activity and regulates transcription through clipping histone H3 N-terminal tail
Histone deacetylase 1 (HDAC1) has been mainly characterized as a factor removing acetyl groups from histone and non-histone proteins as well as inhibiting gene transcription. However, HDAC1 is also involved in positively regulating transcription of particular genes through as yet unknown mechanisms....
ORGANISM(S): Homo sapiens 
2025-12-23 | GSE272621 | GEO
UnknownPRB1 is required for clipping of the histone H3 N terminal tail in Saccharomyces cerevisiae.
Not available
S-EPMC3938757 | biostudies-literature
ProteomicsIntestinal Differentiation Involves Cleavage of Histone H3 NTerminal Tails by Multiple Proteases
The proteolytic cleavage of histone tails, also termed histone clipping, has been described as a mechanism for permanent removal of post-translational modifications (PTMs) from histone proteins. Such activity has been ascribed to ensure regulatory function in key cellular processes such as different...
ORGANISM(S): Mus musculus (Mouse) 
2021-01-11 | PXD022171 | Pride
Histone post-translational modifications Clipping 
ProteomicsA rapid and efficient method for the extraction of histone proteins
Current protocols used to extract and purify histones are notoriously tedious, especially when using yeast cells. Here, we describe the use of a simple filter-aided sample preparation approach enabling histone extraction from yeast and mammalian cells using acidified ethanol, a condition that not on...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2023-08-10 | PXD041524 | Pride
N-terminal clipping Histone extratction Fasp 
ProteomicsHypoxia induces histone clipping and H3K4me3 loss in neutrophil progenitors resulting in long-term impairment of neutrophil immunity
The long-term impact of systemic hypoxia resulting from Acute Respiratory Distress Syndrome (ARDS) on the function of short-lived innate immune cells is unclear. We show that patients 3-6 months after recovering from ARDS have persistently impaired circulating neutrophil effector functions and an in...
ORGANISM(S): Homo sapiens (Human) 
2025-09-22 | PXD065461 | Pride
Epigenetics Neutrophil Hypoxia Reprogramming 
ProteomicsHypoxia induces histone clipping and H3K4me3 loss in neutrophil progenitors resulting in long-term impairment of neutrophil immunity
The long-term impact of systemic hypoxia resulting from Acute Respiratory Distress Syndrome (ARDS) on the function of short-lived innate immune cells is unclear. We show that patients 3-6 months after recovering from ARDS have persistently impaired circulating neutrophil effector functions and an in...
ORGANISM(S): Homo sapiens (Human) 
2025-09-22 | PXD065519 | Pride
Epigenetics Neutrophil Hypoxia Reprogramming 
UnknownUnexpected histone H3 tail-clipping activity of glutamate dehydrogenase.
Not available
S-EPMC3696648 | biostudies-literature
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