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All vertebrates have multiple genes encoding for different CASQ isoforms. Increasing interest has been focused on mammalian and human CASQ genes since mutations of both cardiac (CASQ2) and skeletal (CASQ1) isoforms cause different, and sometime severe, human pathologies Danio rerio (zebrafish) is a ...
ORGANISM(S): Danio rerio (Zebrafish) (Brachydanio rerio) 
2015-11-10 | PXD002455 | Pride
Upon infection of a mammalian host, Plasmodium parasites first replicate inside hepato-cytes, generating thousands of new parasites. Although Plasmodium intra-hepatic devel-opment represents a substantial metabolic challenge to the host hepatocyte, how infected cells respond to and integrate this st...
ORGANISM(S): Homo sapiens (Human) 
2016-04-20 | PXD002269 | Pride
DNA repair by homologous recombination is under stringent cell cycle control. This includes the last step of the reaction, disentanglement of DNA joint molecules (JMs). Previous work has established that JMs resolving nucleases are activated specifically at the onset of mitosis. In case of budding y...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2017-01-21 | PXD005356 | Pride
While the Sec61-complex in the membrane of the human endoplasmic reticulum facilitates translocation of all precursor polypeptides with amino-terminal signal peptides or transmembrane helices, the Sec61-associated translocon-associated protein (TRAP)-complex supports translocation of only a subset o...
ORGANISM(S): Homo sapiens (Human) 
2018-08-09 | PXD008178 | Pride
DNA interstrand crosslinks (ICLs) block replication fork progression by inhibiting DNA strand separation. Repair of ICLs requires sequential incisions, translesion DNA synthesis, and homologous recombination, but the full set of factors involved in these transactions remains unknown. Here we establi...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2016-03-13 | MSV000079577 | MassIVE
The molecular responses of marine mussels to contamination with emergent contaminants in marine ecosystems - the biotoxin Okadaic Acidc and Microplastics - was investigated in experiments with live mussels of the species Perna perna. In total 24 independent biological samples, from 4 experimental co...
ORGANISM(S): Perna perna 
2026-07-16 | PXD071829 | Pride
Various pathways can target nascent or fully synthesized precursor polypeptides to the human endoplasmic reticulum (ER). Typically, they involve cytosolic proteins or complexes and their respective receptors on the ER surface. The signal recognition particle (SRP) and the heterodimeric SRP-receptor...
ORGANISM(S): Homo sapiens (Human) 
2020-03-06 | PXD011993 | Pride
Cancer Cell line - Hela 01 Lysc
ORGANISM(S): Homo Sapiens (human) 
2011-12-31 | PAe003662 | PeptideAtlas
Cancer Cell line - Hela 01 trypsin
ORGANISM(S): Homo Sapiens (human) 
2011-12-31 | PAe003661 | PeptideAtlas
Cancer Cell line - Hela 02 Lysc
ORGANISM(S): Homo Sapiens (human) 
2011-12-31 | PAe003658 | PeptideAtlas
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