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TranscriptomicsTranscriptome sequencing of naked mole rat, Heterocephalus glaber
Deep sequencing of mRNA from naked mole rat Analysis of ploy(A)+ RNA of different specimens: brain, kidney, liver from new born , 4 years old , 20 years old and 4 years old hypoxia-exposed naked mole rat
ORGANISM(S): Heterocephalus glaber 
2011-10-12 | E-GEOD-30337 | biostudies-arrayexpress
TranscriptomicsRNA sequencing reveals differential expression of mitochondrial and oxidation reduction genes in the long-lived naked mole-rat when compared to mice.
The goal was to find genes which are differentially expressed between the naked mole-rat (Heterocephalus glaber) and the wild-type mice liver tissue. The genes which are most differentially expressed may provide a clue for the remarkable differences between naked mole-rat and mouse in terms of longe...
ORGANISM(S): Heterocephalus glaber 
2011-11-07 | E-GEOD-30764 | biostudies-arrayexpress
TranscriptomicsRNA sequencing of sperm extracted from the epididymis in naked mole-rat subordinates, naked mole-rat ex-subordinates, and mice
Naked mole-rat show a strong phenotype of sperm hypo-motility and abnormal morphology. Comparative genomic analyses in our study presenting the telomere-to-telomere genome for the naked mole-rat identified several sperm-gene relaxation and sperm-gene loss events in the NMR. To test the transcriptomi...
ORGANISM(S): Mus musculus 
2026-07-31 | E-MTAB-17270 | biostudies-arrayexpress
ProteomicsIn-gel proteomics to verify amylase protein in naked mole-rat and mouse tissue
As a subterranean eusocial mammal the naked mole-rat faces a particularly challenging environment characterised by patchily available food, low O2 and high CO2 levels. In response, naked mole-rats have evolved a suite of molecular and physiological adaptations to survive extreme hypoxia. We have pre...
ORGANISM(S): Mus musculus (Mouse) Heterocephalus glaber 
2026-10-02 | PXD052477 | Pride
Naked mole-rat Ischaemic heart Glycogen Amylase 
GenomicsPacbio Hifi sequencing of a male cape dune mole-rat kidney sample
One PacBio Hifi sequencing run from the kidney of a single male CDMR (Bathyergus suillus) sample used to make the mBatSui1.1.primary genome assembly as an evolutionary comparator to our telomere-to-telomere naked mole-rat genome assembly. Specifically, we assembled a CDMR from a wild-derived sample ...
ORGANISM(S): Bathyergus suillus 
2026-08-05 | E-MTAB-17312 | biostudies-arrayexpress
GenomicsONT ULK sequencing of a male cape dune mole-rat kidney sample
One ONT-ULK sequencing run from the kidney of a single male CDMR (Bathyergus suillus) sample used to make the mBatSui1.1.primary genome assembly as an evolutionary comparator to our telomere-to-telomere naked mole-rat genome assembly. Specifically, we assembled a CDMR from a wild-derived sample in S...
ORGANISM(S): Bathyergus suillus 
2026-08-05 | E-MTAB-17420 | biostudies-arrayexpress
GenomicsH3K27Ac and CENPA ChIP-seq experiments for the naked mole-rat liver
This data contributes to a telomere-to-telomere genome assembly and annotation of the naked mole-rat, Heterocephalus glaber. To epigenetically annotate centromeres, we performed CENPA ChIP-seq experiments in the male subordinate NMR livers. These experiments included an Input control, and a H3K27Ac ...
ORGANISM(S): Heterocephalus glaber 
2026-08-05 | E-MTAB-17296 | biostudies-arrayexpress
GenomicsPacbio Hifi sequencing of a naked mole-rat male subordinate kidney sample
Two PacBio Hifi sequencing runs from the kidney of a single male NMR sample used to make the mHetGla4.1.primary genome assembly. Specifically, we assembled a second NMR genome from an unrelated male of a separate captive colony in Toronto, Canada, using PacBio HiFi (155.8 Gb, read N50 = 11.45 Kb) an...
ORGANISM(S): Heterocephalus glaber 
2026-08-05 | E-MTAB-17313 | biostudies-arrayexpress
TranscriptomicsBulk RNA-seq datasets of co-injected naked mole rat and human fibroblasts to NSG mice 2022
To study the tumour-suppressive capabilities of naked mole-rat fibroblasts we subcutaneously co-injected the fibroblasts and human squamous carcinoma cells into the flanks of NSG mice, which lack mature T cells. As controls, we (1) performed the co-injection experiment with mouse fibroblasts, and (2...
ORGANISM(S): Homo sapiens 
2023-11-21 | E-MTAB-12455 | biostudies-arrayexpress
ProteomicsNaked mole-rat proteomic analysis
Analysis of the Naked mole-rat proteome relative to mice
ORGANISM(S): Mus Musculus (ncbitaxon:10090) Heterocephalus Glaber (ncbitaxon:10181) 
2020-12-18 | MSV000086617 | MassIVE
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