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MetabolomicsHippophae rhamnoides-Derived Exosome-like Nanovesicles Alleviate Dexamethasone-Induced Sarcopenia by Remodeling Skeletal Muscle Lipid Metabolism
Skeletal muscle atrophy driven by glucocorticoid excess is a clinically relevant contributor to sarcopenia, yet safe and biologically integrated interventions remain limited. Here we report that extracellular exosome-like nanovesicles derived from Hippophae rhamnoides fruits (HR-ELNs) protect agains...
2026-07-17 | MTBLS15070 | MetaboLights
MetabolomicsLC-MS lipidomic characterization of plant-derived exosome-like nanovesicles from ginseng, pueraria lobata, and Chinese yam

This study characterizes the lipid composition of exosome-like nanovesicles isolated from Ginseng, Pueraria lobata, and Chinese yam using LC-MS-based lipidomics. The dataset includes LC-MS raw data and processed lipid annotation and relative quantification tables acquired in both positive and neg...

2026-07-27 | MTBLS14935 | MetaboLights
ProteomicsTunable Plasma Coating Method Modulates Surface Charge and Protein Corona of Cell-Derived Nanovesicles for Improved Systemic Drug Delivery
Tunable Plasma Coating Method Modulates Surface Charge and Protein Corona of Cell-Derived Nanovesicles for Improved Systemic Drug Delivery
ORGANISM(S): Homo sapiens (Human) 
2026-01-27 | PXD071878 | Pride
Human Lc-ms 
ProteomicsPotential, Properties and Sources of Plant Derived Extracellular Vesicles and Nanovesicles
The ascending interest in human extracellular vesicles (EVs) has transferred only a little to plant derived EVs and nanovesicles yet. Although a series of investigations already pointed out promising health beneficial effects and drug delivery properties, adequate (pre)clinical studies are rare. Thi...
ORGANISM(S): Craterostigma plantagineum 
2021-03-30 | PXD024203 | Pride
Extracellular vesicles  plant nanovesicles  exosome-like nanoparticles  plant cell culture  lipids  metabolomics  proteomics 
ProteomicsiPSC nanovesicles cardiac cell repair
Here, we engineered functional EV-like nanovesicles (NVs) from human-induced pluripotent stem cells and highlight their potential as a functional surrogate for natural EVs for tissue repair. Proteome profiling of target cells further identified pathways implicated in angiogenesis (MYH10, AAMP, SLC3A...
ORGANISM(S): Homo sapiens (Human) 
2023-01-15 | PXD036654 | Pride
Proteomics Ipsc Nanovesicles Cardiac repair Cell reprogramming 
ProteomicsMyelin nanovesicles characterization
Neurodegenerative diseases affect millions of people worldwide and the presence of various physiological barriers limits the accessibility to the brain and reduces the efficacy of various therapies. Moreover, improving the solubility, stability and release of the drug in specific brain regions and i...
ORGANISM(S): Rattus norvegicus (Rat) 
2021-12-15 | PXD026282 | Pride
Orbitrap fusion  nanolc 
ProteomicsPlant-Derived Nanovesicles (PDNVs) from Ginkgo biloba Seeds
Plant-derived nanovesicles (PDNVs) were isolated from Ginkgo biloba seed homogenate using differential ultracentrifugation (DUC) followed by density gradient ultracentrifugation (DGUC) with linear and non-linear iodixanol gradients. Nanoparticle tracking analysis (NTA) and cryo-transmission electron...
ORGANISM(S): Ginkgo biloba 
2025-12-18 | PXD072128 | Pride
Proteomics Plant-derived nanovesicles Lc-ms Ginkgo biloba 
ProteomicsBacterial Protoplast-Derived Nanovesicles Carrying CRISPR Cas9 Tools Efficiently Re-educate Tumor-Associated Macrophages for Cancer Immunotherapy
we developed an in vivo CRISPR-Cas9 genome editing system that targets tumor-associated macrophages (TAMs) via bacterial protoplast-derived nanovesicles (NVs) decorated with a pH-responsive PEG conjugated polymer and galactosamine-conjugated ligand
ORGANISM(S): Escherichia Coli Bl21(de3) 
PXD045507 |
ProteomicsProteomic characterisation of extracellular vesicles derived from first trimester placentae
This study investigated the proteomes of macro-, micro- and nanovesicles derived from the same first trimester human placenta to better understand the role that these extracellular vesicles (EVs) play in maternal adaptation during healthy pregnancy. During human pregnancy, the mother undergoes majo...
ORGANISM(S): Homo sapiens (Human) 
2016-04-29 | PXD003003 | Pride
Syncytiotrophoblast Pregnancy Microvesicles Macrovesicles Nanovesicles 
GenomicsSmall RNAs in Exosome-like nanovesicles from Peucedanum japonicum (PjELNs)
Small RNAs in Exosome-like nanovesicles from Peucedanum japonicum (PjELNs)
PRJNA1187462 | ENA
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