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Neuropilin-1+ vs. Neuropilin-1- CD8+ T cells from Plasmodium berghei ANKA-infected mice
During neuronal wiring, extrinsic cues trigger the local translation of specific mRNAs in axons via cell surface receptors. The coupling of ribosomes to receptors has been proposed as a mechanism linking signals to local translation but it is not known how broadly this mechanism operates, nor whethe...
ORGANISM(S): Xenopus laevis (African clawed frog) 
2019-12-02 | PXD015650 | Pride
Characterization of Neuropilin-1+ and Neuropilin-1- splenic CD8+ T cells from Plasmodium berghei ANKA-infected C57BL/6 mice
ORGANISM(S): Mus musculus 
2022-12-31 | GSE199569 | GEO
Regulatory T cells (Treg) represent a critical immunoregulatory component of the immune system. The signals that maintain Treg stability and potentiate their function remain obscure. Here we show that the immune cell surface ligand semaphorin-4a (Sema4a) Sema treated and NRP1 knock outs were compare...
ORGANISM(S): Mus musculus 
To get unbiased insights on the molecular networks through by which Neuropilin 1 (NRP1) controls endothelial cell (EC) and blood vessel functions independently from its ligands, wehave implemented a Halo Tag (HT)-based approach, which enables effective surface labeling and pull-down of proteins, and...
ORGANISM(S): Homo sapiens (Human) 
2022-06-15 | PXD019700 | Pride
Role of Neuropilin-1 in regulatory T cell stability and function
Neuropilin-1 high monocytes protect against neonatal inflammation
Neuropilin-1 is Required for the Suppressive Function of Human Regulatory T Cells
Integrin trafficking to and from membrane adhesions is a crucial mechanism that dictates many aspects of a cell’s behaviour, including motility, polarisation, and invasion. In endothelial cells (ECs), the intracellular traffic of α5-integrin is regulated by both neuropilin 1 (NRP1) and neuropilin 2 ...
ORGANISM(S): Mus musculus (Mouse) 
2024-05-20 | PXD051778 | Pride
Regulatory T cells (Tregs), lymphocytes that suppress immunological reactions, are of great interest for our comprehension of homeostasis and regulation in the immune system and as a therapeutic target in the treatment of both immune-mediated pathologies and reactivation of the immune response in pa...
ORGANISM(S): Homo sapiens 
2019-01-01 | GSE106932 | GEO
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