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ProteomicsLC-MSMS of DCC and Neuropilin-1 immunoprecipitated samples from Xenopus Laevis brains
During neuronal wiring, extrinsic cues trigger the local translation of specific mRNAs in axons via cell surface receptors. The coupling of ribosomes to receptors has been proposed as a mechanism linking signals to local translation but it is not known how broadly this mechanism operates, nor whethe...
ORGANISM(S): Xenopus laevis (African clawed frog) 
2019-12-02 | PXD015650 | Pride
Lc-msms Neuropilin-1 Dcc Xenopus laevis brains Lfq Immunoprecipitation 
GenomicsNeuropilin-1+ vs. Neuropilin-1- CD8+ T cells from Plasmodium berghei ANKA-infected mice
Neuropilin-1+ vs. Neuropilin-1- CD8+ T cells from Plasmodium berghei ANKA-infected mice
PRJNA820739 | ENA
ProteomicsNeuropilin 1 interactome in endothelial cells
To get unbiased insights on the molecular networks through by which Neuropilin 1 (NRP1) controls endothelial cell (EC) and blood vessel functions independently from its ligands, wehave implemented a Halo Tag (HT)-based approach, which enables effective surface labeling and pull-down of proteins, and...
ORGANISM(S): Homo sapiens (Human) 
2022-06-15 | PXD019700 | Pride
Endothelial cells Vessel permeability Ms-proteomics Neuropilin Interactome Blood vessels Cell-cell adhesion 
TranscriptomicsPotentiation of regulatory T cell stability and function via a neuropilin-1:semaphorin-4a axis
Regulatory T cells (Treg) represent a critical immunoregulatory component of the immune system. The signals that maintain Treg stability and potentiate their function remain obscure. Here we show that the immune cell surface ligand semaphorin-4a (Sema4a) Sema treated and NRP1 knock outs were compare...
ORGANISM(S): Mus musculus 
2013-09-06 | E-GEOD-41185 | biostudies-arrayexpress
TranscriptomicsNeuropilin-1+ vs. Neuropilin-1- CD8+ T cells from Plasmodium berghei ANKA-infected mice
Characterization of Neuropilin-1+ and Neuropilin-1- splenic CD8+ T cells from Plasmodium berghei ANKA-infected C57BL/6 mice
ORGANISM(S): Mus musculus 
2022-12-31 | GSE199569 | GEO
GenomicsTranscriptomic profiling of Neuropilin 2-expressing CD4+ T cells
Transcriptomic profiling of Neuropilin 2-expressing CD4+ T cells
PRJNA938097 | ENA
GenomicsCITE-seq of Neuropilin 2-expressing CD4+ T cells
CITE-seq of Neuropilin 2-expressing CD4+ T cells
PRJNA938099 | ENA
ProteomicsA proteomics approach to isolating neuropilin-dependent α5 integrin trafficking pathways: neuropilin 1 and 2 co-traffic α5 integrin through endosomal p120RasGAP to promote polarised fibronectin fibrillogenesis in endothelial cells
Integrin trafficking to and from membrane adhesions is a crucial mechanism that dictates many aspects of a cell’s behaviour, including motility, polarisation, and invasion. In endothelial cells (ECs), the intracellular traffic of α5-integrin is regulated by both neuropilin 1 (NRP1) and neuropilin 2 ...
ORGANISM(S): Mus musculus (Mouse) 
2024-05-20 | PXD051778 | Pride
Sprouting angiogenesis Integrin trafficking Neuropilins Endothelial cell Retina 
GenomicsRole of Neuropilin-1 in regulatory T cell stability and function
Role of Neuropilin-1 in regulatory T cell stability and function
PRJNA831659 | ENA
ProteomicsNeuropilin-2 (NRP2) is the receptor for human cytomegalovirus (HCMV) pentameric complex and is responsible for HCMV infection
Chemical cross-linking coupled to mass spectrometry was used to study the complex between the HMCV pentameric complex (gH/gL/UL128/UL130/UL131A) and its receptor, neuropilin-2 (NRP2). Cross-linking was performed using either disuccinimidyl suberate (DSS) or a combination of pimelic acid dihydrazide ...
ORGANISM(S): Homo sapiens (Human) 
2018-07-26 | PXD007185 | Pride
Chemical cross-linking  dss  structural proteomics  human cytomegalovirus  viral entry  receptor proteins 
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