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Metabolomics2 hydroxyglutarate prodution in neurospheres from IDH1 mouse glioma model #2
Not available
ORGANISM(S): Mus musculus 
ST000820 | MetabolomicsWorkbench
ProteomicsQuantitative profiling of axonal guidance proteins during the differentiation of human neurospheres
Axon guidance is required for the establishment of brain circuits. Whether much of the molecular basis of axon guidance is known from animal models, the molecular machinery coordinating axon growth and pathfinding in humans remains to be elucidated. The use of induced pluripotent stem cells (iPSC) f...
ORGANISM(S): Homo sapiens (Human) 
2021-02-25 | PXD024177 | Pride
Neural stem cells (nsc) Human neurospheres Axon guidance Itraq-based quantitative proteomics Human induced pluripotent stem cells Neural differentiation 
ProteomicsComparative proteomics between 2D and 3D (neurospheres) cultured NSCs
Neurospheres are a relevant 3D model with many applications, but it lacks sufficient omics studies. Here, we performed a comparative proteomics experiment to investigate what distinguishes a 2D from a 3D culture of Neural Stem Cells (NSCs). In both cases, NSCs were iPSC-derived.
ORGANISM(S): Homo sapiens (Human) 
2026-01-20 | PXD063185 | Pride
Tmt Neurospheres Lc-msms 
TranscriptomicsTranscription profiling of mouse primary neural stem cells (neurospheres) originating from separate isolations (individuals), different passages and parallel cultures
Investigation of transcriptome variability in neurospheres originating from separate isolations (individuals), different passages and parallel cultures. As a control neurospheres were also compared to neurospheres induced to differentiate by adding serum and plating onto solid support.
ORGANISM(S): Mus musculus 
2005-03-31 | E-MEXP-297 | biostudies-arrayexpress
ProteomicsZIKV infection of human neurospheres
Zika virus (ZIKV) has been associated with microcephaly and other brain abnormalities; however, the molecular consequences of ZIKV to human brain development are still not fully understood. Here we describe alterations in human neurospheres derived from induced pluripotent stem (iPS) cells infected ...
ORGANISM(S): Homo sapiens (Human) 
2018-10-27 | PXD004588 | Pride
Microcephaly Ipsc Human Zika 
TranscriptomicsTranscription profiling of human neurospheres and adherent cells derived from a human glioblastoma multiforme primary tumour
Comparison of gene expression patterns between neurospheres and adherent cells derived from a glioblastoma multiforme primary tumour
ORGANISM(S): Homo sapiens 
2006-12-31 | E-MEXP-551 | biostudies-arrayexpress
GenomicsATAC-seq for Pantr2 knockout cortical neurospheres
ATAC-seq for Pantr2 knockout cortical neurospheres
PRJNA863896 | ENA
ProteomicsHuman neurospheres ZIKV infection
Zika virus (ZIKV) has been associated with microcephaly and other brain abnormalities; however, the molecular consequences of ZIKV to human brain development are still not fully understood. Here we describe alterations in human neurospheres derived from induced pluripotent stem (iPS) cells infected ...
ORGANISM(S): Homo sapiens (Human) 
2018-08-29 | PXD010866 | Pride
Microcephaly Neuron Stem cell Zika virus 
TranscriptomicsExpression analysis of big neurospheres generated in vitro
Expression analysis of neurospheres generated in vitro treated by potassium chloride (KCl) and norepinephrine Neurospheres generated in vitro were treated with norepinephrine or potassium chloride. Gene expression analysis was then carried out to identify genes that are up or down regulated due to c...
ORGANISM(S): Mus musculus 
2015-06-12 | E-GEOD-67304 | biostudies-arrayexpress
TranscriptomicsE14.5 mouse cortical neurospheres in response to Fezf2 over-expression
RNA Sequencing of E14.5 mouse cortical neurospheres in response to Fezf2 over-expression 2 replicates each of GFP-transfected or Fezf2/GFP-transfected E14.5 mouse cortical neurospheres. Paired-end sequencing 101bp.
ORGANISM(S): Mus musculus 
2014-07-06 | E-GEOD-56446 | biostudies-arrayexpress
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