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TranscriptomicscDNA microarray analysis of splenic B220+CD138+ plasma cells from K/BxNsf and K/BxN mice
Long-lived plasma cells (LLPCs) develop under the help of follicular helper T (Tfh) cells and reside mainly in the bone marrow. However, these cells are unusually abundant in the spleen of several autoimmune models including K/BxNsf mice, yet their pathogenic impact remains unknown. To investigate a...
ORGANISM(S): Mus musculus 
2016-03-01 | E-GEOD-66947 | biostudies-arrayexpress
UnknownPharmacokinetic variability of 20(S)-protopanaxadiol-type ginsenosides Rb1, rd, and compound K from Korean red ginseng in experimental rodents.
Not available
S-EPMC12316956 | biostudies-literature
ProteomicsUbiquitin-mediated modulation of necroptotic effector MLKL
We aimed to identify lysine (K) residues that are endogenously ubiquitylated upon TNF-induced necroptosis. To this end, we used a quantitative mass spectrometry-based approach. Briefly, MDFs were treated with TSZ or left untreated and protein lysates were digested with trypsin into peptides. Ubiquit...
ORGANISM(S): Mus musculus (Mouse) 
2021-04-13 | PXD018857 | Pride
Ubiquitin Tmt Cancer Mlkl Mouse Msms 
UnknownDiagnostic Performance of Alpha-Fetoprotein, Protein Induced by Vitamin K Absence, Osteopontin, Dickkopf-1 and Its Combinations for Hepatocellular Carcinoma.
Not available
S-EPMC4795737 | biostudies-literature
ProteomicsHuman LMO2 binding protein LC-MSMS in U87MG(Glioblastoma cell)
To identify the binding partner of LMO2 for explanation of STAT3 signal-related protein in human glioblastoma
ORGANISM(S): Homo sapiens (Human) 
2022-08-11 | PXD028254 | Pride
Human Lmo2 Glioblastoma 
TranscriptomicsIdentification of DNA Methylation Markers for Lineage Commitment of in vitro Hepatogenesis [methylation profiling]
Hepatocytes that have differentiated from human embryonic stem cells have great potential for the treatment of liver disease as well as for drug testing. Moreover, in vitro hepatogenesis is a powerful model system for studying the molecular mechanisms underlying liver development. DNA methylation is...
ORGANISM(S): Homo sapiens 
2011-06-10 | E-GEOD-25047 | biostudies-arrayexpress
TranscriptomicsIdentification of DNA Methylation Markers for Lineage Commitment of in vitro Hepatogenesis [mRNA profiling]
Hepatocytes that have differentiated from human embryonic stem cells have great potential for the treatment of liver disease as well as for drug testing. Moreover, in vitro hepatogenesis is a powerful model system for studying the molecular mechanisms underlying liver development. DNA methylation is...
ORGANISM(S): Homo sapiens 
2011-06-10 | E-GEOD-25046 | biostudies-arrayexpress
ProteomicsT2D patients’ urine LC-MSMS for predicting prognosis w/ and w/o renal dysfunction
Renal dysfunction and its functional regression have been known as one of major complication of type 2 diabetes (T2D). The prognosis for kidney function can be determined by estimated glomerular filtration rate (eGFR) and the known protein makers such as albumin and those parameters can classy patie...
ORGANISM(S): Homo sapiens (Human) 
2020-06-23 | PXD016571 | Pride
Human Lc-msms Diabetes mellitus type 2 Kidney Diabetic nephropathy Urine 
TranscriptomicsRenoprotective Effects of Valproic Acid and Dexamethasone in Acute Kidney Ischemia-Reperfusion Injury
Introduction: Renal ischemia-reperfusion (IR) causes acute kidney injury (AKI) with high mortality and morbidity. The objective of this study was to ameliorate kidney IR injury and identify novel biomarkers for kidney injury and repair. Methods: Left renal ischemia was induced in rats by clamping re...
ORGANISM(S): Rattus norvegicus 
2015-07-06 | E-GEOD-58438 | biostudies-arrayexpress
UnknownModulation of renal inflammation and tubular injury by calcitriol in patients with early diabetic kidney disease: a randomized controlled trial.
Not available
S-EPMC12570221 | biostudies-literature
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