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ProteomicsDiversity and Heterogeneity of Extracellular Vesicles and Brain-Penetrating Amembranous Non-Vesicular Nanoparticles in Glioblastoma
Advances in understanding intercellular communication through extracellular vesicles (EVs) and non-vesicular extracellular nanoparticles (NVEPs) have been limited by their cellular heterogeneity and unclear origins. Using sequential ultracentrifugation, we identified high- and low-density EVs and pe...
ORGANISM(S): Homo sapiens (Human) 
2025-10-13 | PXD059671 | Pride
Supermeres Extracellular nanoparticles Exomeres Extracellular vesicles Glioblastoma Egfr 
GenomicsDiversity and Heterogeneity of Extracellular Vesicles and Brain-Penetrating Amembranous Non-Vesicular Nanoparticles in Glioblastoma
Diversity and Heterogeneity of Extracellular Vesicles and Brain-Penetrating Amembranous Non-Vesicular Nanoparticles in Glioblastoma
PRJNA1209840 | ENA
ProteomicsContracting Skeletal Muscle Releases Antioxidant-Enriched Extracellular Vesicles and Non-vesicular Extracellular Nanoparticles
This study investigated extracellular vesicles and non-vesicular extracellular nanoparticles released from C2C12 skeletal muscle myotubes following electrical pulse stimulation (EPS). Quantitative proteomics was used to characterize protein profiles and identify changes associated with EPS and antio...
ORGANISM(S): Mus musculus (Mouse) 
2026-09-14 | PXD084099 | Pride
C2c12 Proteomics Electrical pulse stimulation Non-vesicular extracellular nanoparticles Extracellular vesicles Skeletal muscle Data-independent acquisition 
TranscriptomicsDiversity and Heterogeneity of Extracellular Vesicles and Brain-Penetrating Amembranous Non-Vesicular Nanoparticles in Glioblastoma
Advances in understanding intercellular communication through extracellular vesicles (EVs) and non-vesicular extracellular nanoparticles (NVEPs) have been limited by their cellular heterogeneity and unclear origins. Using sequential ultracentrifugation, we identified high- and low-density EVs and pe...
ORGANISM(S): Homo sapiens 
2025-11-18 | GSE286513 | GEO
UnknownHeterogeneity of Extracellular Vesicles and Non-Vesicular Nanoparticles in Glioblastoma.
Not available
S-EPMC12491655 | biostudies-literature
ProteomicsA High-Resolution Proteomic Atlas of Extracellular Vesicles and Non-Vesicular Particles
Extracellular vesicles (EVs) are key mediators of intercellular communication and promising biomarkers. However, their molecular characterization remains challenging due to the heterogeneity of EV subtypes and co-isolated nanoparticles. Here, leveraging protein correlation profiling along density gr...
ORGANISM(S): Homo sapiens (Human) 
2025-12-30 | PXD062547 | Pride
Density gradient Proteomics Extra-cellular vesicles Biofluids Cancer cells 
ProteomicsA High-Resolution Proteomic Atlas of Extracellular Vesicles and Non-Vesicular Particles
Extracellular vesicles (EVs) are key mediators of intercellular communication and promising biomarkers. However, their molecular characterization remains challenging due to the heterogeneity of EV subtypes and co-isolated nanoparticles. Here, leveraging protein correlation profiling along density gr...
ORGANISM(S): Homo sapiens (Human) 
2025-12-30 | PXD062477 | Pride
Density gradient Proteomics Extra-cellular vesicles Biofluids Cancer cells 
TranscriptomicsComparative transcriptomic analysis of human and Drosophila extracellular vesicles reveals extensive conservation
Extracellular vesicles (EVs) are membrane-enclosed nanoparticles containing specific repertoires of genetic material. In mammals, EVs can mediate the horizontal transfer of various cargos and signaling molecules, notably miRNA and mRNA species. Whether this form of intercellular communication prevai...
ORGANISM(S): Homo sapiens 
2016-06-15 | E-GEOD-76173 | biostudies-arrayexpress
ProteomicsSupermeres, a new functional extracellular nanoparticle replete with disease biomarkers and therapeutic target
Extracellular vesicles, including exosomes, and exomere nanoparticles, are under intense investigation for cargo that may serve as clinical biomarkers or therapeutic targets. Here, we report discovery of a new extracellular nanoparticle, termed supermeres. We performed LC/MS-MS proteomics analyses o...
ORGANISM(S): Homo sapiens (Human) 
2021-11-02 | PXD025213 | Pride
Human Sev Supermere Exomere Difi Colorectal cancer Lc-ms/ms 
UnknownExtracellular vesicles and nanoparticles at a glance.
Not available
S-EPMC11658686 | biostudies-literature
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