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ProteomicsDifferential Effects of Cocaine and Morphine on the Diurnal Regulation of the Mouse Nucleus Accumbens Proteome
Substance use disorders (SUDs) are associated with disruptions in sleep and circadian rhythms that persist during abstinence and may contribute to relapse risk. Repeated use of substances such as psychostimulants and opioids may lead to significant alterations in molecular rhythms in the nucleus acc...
ORGANISM(S): Mus musculus (Mouse) 
2023-07-20 | PXD042043 | Pride
Nucleus accumbens Proteomics Cocaine Morphine Circadian rhythms 
ProteomicsThe proteomic landscape of parkin-deficient and parkin-overexpressing rat nucleus accumbens: an insight into the role of parkin in methamphetamine use disorder
In recent years, methamphetamine (METH) misuse in the US has been rapidly increasing, and there is no FDA-approved pharmacotherapy for METH use disorder (MUD). We previously determined that ubiquitin-protein ligase parkin is involved in the regulation of METH addictive behaviors in rat models of MUD...
ORGANISM(S): Rattus norvegicus (Rat) 
2025-08-04 | PXD065059 | Pride
Parkin  proteome  nucleus accumbens  mitochondria  methamphetamine 
ProteomicsM.musculus - Suprachiasmatic nucleus, iBAQ (Chiangetal,plosgenetics.2014)
abundance based on iBAQ, Interaction consistency score: 15.5, Coverage: 18
ORGANISM(S): 10090 
2014-00-00 | 1300563876 | PAXDB
ProteomicsThe Nuclear Proteome of a Vertebrate
Despite the nucleus’ central role in multi-cellular biology, it is still poorly understood how the cell’s proteome is partitioned between the nucleus and cytoplasm. This is mostly due to the difficulty of separating the nuclear and cytoplasmic contents and the challenge to comprehensively measure re...
ORGANISM(S): Xenopus laevis (African clawed frog) 
2015-09-17 | PXD001297 | Pride
Nucleus Tmtc Xenopus Multinotchms3 
ProteomicsLC-MS Based Draft Map of the Arabidopsis thaliana Nuclear Proteome and Protein Import in Pattern Triggered Immunity
An LC-MS based discovery proteomics approach was used to measure the nuclear proteome fractions of Arabidopsis thaliana cell culture. An enrichment score based on the relative abundance of cytoplasmic, mitochondrial and golgi markers in the nuclear protein fraction allowed us to curate the nuclear p...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2021-11-08 | PXD024349 | Pride
Arabidopsis thaliana  nucleus  nuclear proteome  stress response  flg22  nlp20 
UnknownDifferential Effects of Cocaine and Morphine on the Diurnal Regulation of the Mouse Nucleus Accumbens Proteome.
Not available
S-EPMC10392613 | biostudies-literature
ProteomicsIdentifying Nucleus Accumbens Dysfunction in a novel mouse model of Female Social Defeat Stress (femCSDS) through proteomic profile
High-resolution label-free quantitative proteomics was performed on microdissected nucleus accumbens (NAc) tissue from female Mus musculus (C57BL/6NCrl) aged 6-8 weeks, subjected to a female chronic social defeat stress (femCSDS) paradigm and matched controls.
ORGANISM(S): Mus musculus (Mouse) 
2026-07-25 | PXD074507 | Pride
Nucleus accumbens Mice Stress 
UnknownComprehensive nuclear proteome of Arabidopsis obtained by sequential extraction.
Not available
S-EPMC6527390 | biostudies-literature
TranscriptomicsMaternal age effect on mouse oocytes: new biological insight from proteomic analysis
The long-standing view of 'immortal germ line versus mortal soma' poses a fundamental question in biology concerning how oocytes age in molecular terms. A mainstream hypothesis is that maternal aging of oocytes has its roots in gene transcription. Investigating the proteins resulting from mRNA trans...
ORGANISM(S): Mus musculus 
2014-04-15 | E-GEOD-42959 | biostudies-arrayexpress
UnknownIntegrated transcriptome and proteome analyses identify novel regulatory network of nucleus pulposus cells in intervertebral disc degeneration.
Not available
S-EPMC7860219 | biostudies-literature
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