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MetabolomicsLiquid chromatography coupled to high-resolution mass spectrometry metabolomics: A useful tool for investigating tumor secretome based on a three-dimensional co-culture model

Three-dimensional (3D) cell culture technologies, which more closely mimic the complex microenvironment of tissue, are being increasingly evaluated as a tool for the preclinical screening of clinically promising new molecules, and studying of tissue metabolism. Studies of metabolites released int...

2023-12-12 | MTBLS5375 | MetaboLights
UnknownCarbocation catalysis in confined space: activation of trityl chloride inside the hexameric resorcinarene capsule.
Not available
S-EPMC9337730 | biostudies-literature
ProteomicsIntegrative structural analysis defines how LRPAP1 modulates ligand binding in LRP2
The low density lipoprotein receptor-related protein 2 (LRP2 or megalin) is a multiligand endocytic receptor implicated in the homeostasis of several organs. Mutations in the LRP2 gene are associated with severe systemic disease. It is well-know that the low density lipoprotein receptor-related prot...
ORGANISM(S): Homo sapiens (Human) 
2026-03-21 | PXD066532 | Pride
Crosslinking ms Cross-linking ms Megalin Lrpap1 Xl-ms Endocytosis Lrp2 Rap 
ProteomicsIntegrative structural analysis defines how LRPAP1 modulates ligand binding in LRP2 (Dataset 3)
The low density lipoprotein receptor-related protein 2 (LRP2 or megalin) is a multiligand endocytic receptor implicated in the homeostasis of several organs. Mutations in the LRP2 gene are associated with severe systemic disease. It is well-know that the low density lipoprotein receptor-related prot...
ORGANISM(S): Homo sapiens (Human) 
2026-03-21 | PXD066538 | Pride
Crosslinking ms Cross-linking ms Megalin Lrpap1 Xl-ms Endocytosis Lrp2 Rap 
ProteomicsIntegrative structural analysis defines how LRPAP1 modulates ligand binding in LRP2 (Dataset 1)
The low density lipoprotein receptor-related protein 2 (LRP2 or megalin) is a multiligand endocytic receptor implicated in the homeostasis of several organs. Mutations in the LRP2 gene are associated with severe systemic disease. It is well-know that the low density lipoprotein receptor-related prot...
ORGANISM(S): Homo sapiens (Human) 
2026-03-21 | PXD066475 | Pride
Crosslinking ms Cross-linking ms Megalin Lrpap1 Xl-ms Endocytosis Lrp2 Rap 
ProteomicsCrosslinking MS dataset of the Eukaryotic Core m6A Methyltransferase Complex
RNA modifications are critical post-transcriptional regulators of gene expression, impacting diverse biological processes. Among these, N6-methyladenosine (m⁶A ) is the predominant mRNA mark, installed at DRACH motifs by a conserved multi-protein Methyltransferase Complex (MTC). Although structures ...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2026-10-07 | PXD067875 | Pride
Rna methyltransferase Crosslinking ms Rna modification Crosslinking mass spectrometry M6a Xl-ms Meiosis 
TranscriptomicsTranscription profiling of inducible overexpression of Arabidopsis meristem regulators by AlcR / AlcA system in continuous light
Inducible overexpression of Arabidopsis meristem regulators by AlcR / AlcA system. Plants harboring 35S::AlcR/AlcA::GOI (GUS control, LEAFY, SHOOTMERSTEMLESS, WUSCHEL)constructs were grown in continous light for 12 days and induced with 1% Ethanol. After 12h of EtOH treatment, seedlings were dissect...
ORGANISM(S): Arabidopsis thaliana 
2006-01-01 | E-MEXP-432 | biostudies-arrayexpress
UnknownCopper(II) Complexes with Carnosine Conjugates of Hyaluronic Acids at Different Dipeptide Loading Percentages Behave as Multiple SOD Mimics and Stimulate Nrf2 Translocation and Antioxidant Response in In Vitro Inflammatory Model.
Not available
S-EPMC10452038 | biostudies-literature
UnknownRedox Sensing within the Genus Shewanella.
Not available
S-EPMC5789149 | biostudies-literature
TranscriptomicsTranscription profiling by array of Burkholderia cenocepacia J2315 was exposed to heat stress and to stress form reactive oxygen species
B. cenocepacia J2315 was exposed to heat stress and to stress form reactive oxygen species.
To expose the cultures to heat stress, cells were grown at 37ºC to an O.D. of 0.4 to 0.45 and then transferred into a different shaking incubator at 42.5ºC, incubated for 1 hour at 150 rpm and harvested.<...
ORGANISM(S): Burkholderia cenocepacia 
2012-01-01 | E-MEXP-2791 | biostudies-arrayexpress
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